CAS: 3646-68-2; (2R,3R,4S,5R)-2-Amino-3,4,5,6-Tetrahydroxyhexanoic Acid

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CAS号338-69-2 D-丙氨酸 | CAS号669-90-9 D-阿拉伯-2-己糖醛酸 | CAS号1078691-95-8 2-Amino-2-deoxy... | CAS号3416-24-8 氨基葡萄糖 | CAS号83078-98-2 2-amino-O4,O6-(... | CAS号74-90-8 氢氰酸 | CAS号90-76-6 (3R,4R,5R,6R)-3... | CAS号66-84-2 氨基葡萄糖盐酸盐 | CAS号108-24-7 乙酸酐 | CAS号3416-24-8 氨基葡萄糖 | CAS号10323-20-3 D-阿拉伯糖 | CAS号583-50-6 D-赤藓糖 | CAS号10326-41-7 D-乳酸 | CAS号110-15-6 琥珀酸； 丁二酸 | CAS号144-62-7 草酸 | CAS号64-19-7 冰醋酸

D-氨基葡萄糖盐酸盐置于sodium Chlorite,溶剂黄146体系中,化学反应生成 D-氨基葡萄糖酸
参考文献:Ebata,Science Reports Of Kanazawa University,1955,Vol. 4,P. 41,43
标题:Ebata,Science Reports Of Kanazawa University,1955,Vol. 4,P. 41,43

专利信息

专利号:US-2004053999-A1
优先权日:1997-09-17
标题 :Novel compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:US-6225341-B1
优先权日:1995-02-27
标 题:Compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; WILLIAMS MATTHEW A
权利人:GILEAD SCIENCES INC
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:US-7858775-B2
优先权日:2003-06-24
标 题:Production of 2′-deoxynucleosides and 2′-deoxynucleoside precursors from 2-dehydro-3-deoxy-D-gluconate
发明人：DORING VOLKER; THIBAUT DENIS; KREIMEYER ANNETT; MARLIERE PHILIPPE
权利人:RHODIA CHIMIE SA; EVOLOGIC S A MARLIERE TECHNOLOGIES SOC CIV ILE
摘要:This invention relates to a process for preparing 2′-deoxynucleoside compounds or 2′-deoxynucleoside precursors using 2-dehydro-3-deoxy-D-gluconic acid (usually abbreviated as KDG) or its salts as a starting material. A variety of 2′-deoxynucleosides and their analogues are used as a starting material for synthesis or drug formulation in production of an antiviral, anticancer or antisense agent.

专利号:US-5656745-A
优先权日:1993-09-17
标题:Nucleotide analogs
发明人：BISCHOFBERGER NORBERT; JONES ROBERT J; ARIMILLI MURTY; LIN KUEI-YING; LOUIE MICHAEL; MCGEE LAWRENCE R; PRISBE ERNEST J
权利人:GILEAD SCIENCES INC
摘要:Nucleotide analogs characterized by the presence of an amidate linked amino acid or an ester linked group which is bonded to the phosphorus atom of phosphonate nucleotide analogs are disclosed. The analogs comprise a phosphoamidate or ester bond that is hydrolyzed in vivo to yield a corresponding phosphonate nucleotide analog. Methods and intermediates for their synthesis and use are described.

专利号:EP-0719273-B1
优先权日:1993-09-17
标题:Nucleotide analogs
发明人：BISCHOFBERGER NORBERT W; JONES ROBERT J; ARIMILLI MURTY N; LIN KUEI-YING; LOUIE MICHAEL S; MCGEE LAWWRENCE R; PRISBE ERNEST J; LEE WILLIAM A; CUNDY KENNETH C
权利人:GILEAD SCIENCES INC
摘要:Nucleotide analogs characterized by the presence of an amidate linked amino acid or an ester linked group which is bonded to the phosphorus atom of phosphonate nucleotide analogs are disclosed. The analogs comprise a phosphoamidate or ester bond that is hydrolysed in vivo to yield a corresponding phosphonate nucleotide analog. Methods and intermediates for the synthesis and use are described.