CAS: 14259-47-3; (S)-5-Hydroxy-2-(4-Methoxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-Trihydroxy-6-Methyltetrahydro-2H-Pyran-2-yl)Oxy)Methyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Chroman-4-One

该化合物是主要在柑橘水果中发现的氟氯素化合物,是氟氯素二聚物的甘蓝表面,这意味着它由一种与糖分子相连的氟氯素组成.Didymin以其潜在的健康惠益而著称,包括抗氧化物特性,有助于消除体内自由基的危害;它也可能表现出抗炎效应,并研究其在心血管健康中的潜在作用.该化合物在有机溶剂中溶解,但水溶解性有限,这可能影响其生物利用率.Didymin经常研究其药理特性,特别是在补充饮食和自然健康产品方面.其安全特征一般被认为是有利的,尽管为了充分理解其影响和人体健康的行动机制,有必要进行进一步研究.同许多氟化物一样,五烯的生物活性可能受到剂量,配方和个人代谢差异等因素的影响.

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    专利信息


    专利号:US-11773128-B2
    优先权日:2019-03-28
    标题 :Electrocatalytic synthesis of dihydrochalcones
    发明人:REDKO MIKHAIL; SAFFRON CHRISTOPHER M; JACKSON JAMES E
    权利人:UNIV MICHIGAN STATE
    摘要:The disclosure relates to methods of forming a dihydrochalcone using electrocatalytic dehydrogenation. In particular, the disclosure relates to methods of forming a dihydrochalcone electrocatalytically hydrogenating (ECH) a reactant compound over a catalytic cathode in a reaction medium having a non-alkaline pH value, thereby forming a dihydrochalcone product; wherein the reactant compound has a structure according to Formula (I). The method can be used to prepare dihydrochalcone sweeteners, such as, for example, naringin dihydrochalcone and neohesperidin dihydrochalcone.

    专利号:CN-119331888-A
    优先权日:2024-10-10
    标题:Polygonatum cyrtonema PcF3H gene and application thereof in promotion of synthesis of dihydroflavonoid compounds and catalysis of naringenin hydroxylation

    专利号:US-2022089630-A1
    优先权日:2019-03-28
    标 题 :Electrocatalytic synthesis of dihydrochalcones

    专利号:EP-3947781-A1
    优先权日:2019-03-28
    标题 :Electrocatalytic synthesis of dihydrochalcones

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    合成参考文献


    参考文献:10.18632/oncotarget.15204
    摘要:Singhal SS, Singhal S, Singhal P, Singhal J, Horne D, Awasthi S. Didymin: an orally active citrus flavonoid for targeting neuroblastoma. Oncotarget. 2017 Apr 25;8(17):29428–41.
    参考文献:10.1038/s41592-019-0358-2]
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