CAS: 13532-77-9; 5-Amino-2,2-Dimethylpentan-1-Ol

该化合物是一种环环状氨醇,主要有矿和氢氧功能组,为合成应用提供多种反应.其结构以四碳中心为特点,增强了消毒稳定性,使其在为非对称催化而准备手性中间体或皮条动物方面有所助益.化合物的双重功能允许选择性的修改,使其在制药,农用化学品或特殊聚合物中使用.在β位置的二甲基替代可以提高生物活性衍生物的代谢稳定性.它适合于核分裂反应或作为循环合成的建筑块,它为定制分子设计提供了一种再活性和分子控制的平衡.

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CAS号25252-68-0 4.4-二甲基-5-羟基戊腈

合成工艺路线路线简述

  • 合成目标产物 5-Amino-2,2-Dimethylpentanol 主要起始原料 5-Hydroxy-4,4-Dimethylvaleronitrile
  • (文献来源)合成步骤主要原料 5-Hydroxy-4,4-Dimethylvaleronitrile
📜4.4-二甲基-5-羟基戊腈置于镍 氨,氢气体系中,用 乙醇 用作溶剂,化学反应生成5-氨基-2,2-二甲基戊醇
参考文献:Mileo,J.-C. Et Al.,Comptes Rendus Des Seances De L'Academie Des Sciences,Serie C: Sciences Chimiques,1969,Vol. 268,P. 1949-1952
标题:Mileo,J.-C. Et Al.,Comptes Rendus Des Seances De L'Academie Des Sciences,Serie C: Sciences Chimiques,1969,Vol. 268,P. 1949-1952

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专利信息


专利号:WO-0140193-A1
优先权日:1999-12-03
标题:Method for the synthesis of pyrazolines
发明人:BOLDI ARMEN M
权利人:CHEMRX ADVANCED TECHNOLOGIES I; BOLDI ARMEN M
摘要:The present invention provides a method for the synthesis of compounds of Formula (I). Also claimed are novel intermediates and their methods of synthesis.

专利号:US-2002103381-A1
优先权日:2000-11-30
标 题 :Method for the synthesis of pyrazolines
发明人:BOLDI ARMEN M
摘要:The present invention provides a method for the synthesis of compounds of Formula I: n n n Also claimed are novel intermediates and their methods of synthesis.

专利号:US-8877977-B2
优先权日:2011-11-25
标题 :Synthesis of polyalkylenepolyamines having a low color index by homogeneously catalyzed alcohol amination in the presence of hydrogen
发明人:STRAUTMANN JULIA; SCHAUB THOMAS; HUEFFER STEPHAN; MAAS STEFFEN; PACIELLO ROCCO
权利人:STRAUTMANN JULIA; SCHAUB THOMAS; HUEFFER STEPHAN; MAAS STEFFEN; PACIELLO ROCCO; BASF SE
摘要:Process for the preparation of polyalkylenepolyamines by homogeneously catalyzed alcohol amination, in which aliphatic amino alcohols are reacted with one another or aliphatic diamines or polyamines are reacted with aliphatic diols or polyols with the elimination of water in the presence of a homogeneous catalyst and in the presence of hydrogen gas. Polyalkylenepolyamines obtainable by such processes and polyalkylenepolyamines comprising hydroxy groups, secondary amines or tertiary amines. Uses of such polyalkylenepolyamines as adhesion promoters for printing inks, adhesion promoters in composite films, cohesion promoters for adhesives, crosslinkers/curing agents for resins, primers for paints, wet-adhesion promoters for emulsion paints, complexing agents and flocculating agents, penetration assistants in wood preservation, corrosion inhibitors, immobilizing agents for proteins and enzymes.

专利号:WO-2013076053-A1
优先权日:2011-11-25
标题:Synthesis of polyalkylene polyamines with low color index by homogeneously catalyzed alcohol amination in the presence of hydrogen
发明人:STRAUTMANN JULIA; SCHAUB THOMAS; HUEFFER STEPHAN; MAAS STEFFEN; PACIELLO ROCCO
权利人:BASF SE; STRAUTMANN JULIA; SCHAUB THOMAS; HUEFFER STEPHAN; MAAS STEFFEN; PACIELLO ROCCO
摘要:The invention relates to a method for the production of polyalkylene polyamines by homogeneously catalyzed alcohol amination, wherein aliphatic alkanolamines are reacted with each other or aliphatic diamines or polyamines are reacted with aliphatic diols or polyols in the presence of a homogeneous catalyst while eliminating water and in the presence of hydrogen gas. The invention further relates to polyalkylene polyamines, which can be obtained by said methods, and to polyalkylene polyamines which contain hydroxyl groups, secondary amines or tertiary amines. The invention finally relates to uses of said polyalkylene polyamines as adhesion promoters in inks, adhesion promoters in composite films, cohesion promoters in adhesives, cross-linkers/hardeners for resins, primers for paints, wet adhesion promoters for dispersion paints, complexing agents and flocculants, penetration auxiliaries for use in wood preservation, corrosion inhibitors, and immobilization agents of proteins and enzymes.

专利号:EP-2782949-A1
优先权日:2011-11-25
标题 :Synthesis of polyalkylene polyamines with low color index by homogeneously catalyzed alcohol amination in the presence of hydrogen

专利号:KR-20140098204-A
优先权日:2011-11-25
标题 :Synthesis of polyalkylene polyamines with low color index by homogeneously catalyzed alcohol amination in the presence of hydrogen

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