CAS: 105-87-3; (E)-3,7-Dimethylocta-2,6-Dien-1-Yl Acetate

该化合物是一种有机化合物,被归类为酯类,具体地说,是热兰醇的乙酸盐,其特征是,它具有令人愉快的果味芳香,经常与柑橘和花粉有关,使其在香水,化妆品和调味品中成为流行成分.热兰酸盐的分子配方为C12H22O2, 其分子重量约为198.31克/摩尔.这种化合物一般是无色的,可粉色黄色液体,在水中溶解,但在有机溶剂中可溶.Geranyl 乙酸盐因其挥发性而闻名,有助于其在香味应用中发挥作用.此外,它具有抗微生物特性,可以增强其在各种配方中的效用.在适当浓度中使用该化合物时,一般认为是安全的,但可能会引起某些人的皮肤刺激.其合成通常涉及用乙酸或乙酸醋酸酐的蒸发酵,突出其在自然和合成化学环境中的相关性.

结构式图片

相似化合物

141-12-8 106-24-1 106-25-2

欧盟法规

欧盟化妆品法规附录三-限用物质清单REACH注册ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号106-24-1 香叶醇; (E)-3,7-二甲... | CAS号75-36-5 乙酰氯 | CAS号108-05-4 乙酸乙烯酯 | CAS号106-25-2 橙花醇 | CAS号108-24-7 乙酸酐 | CAS号141-78-6 乙酸乙酯 | CAS号59632-99-4 3,7-dimethyl-1-... | CAS号24529-80-4 acetic acid,4-c... | CAS号35189-96-9 magnesium,2-met... | CAS号78-70-6 芳樟醇 | CAS号105831-41-2 acetic acid,3,7... | CAS号494-90-6 薄荷呋喃 | CAS号141891-13-6 2,6,6-trimethyl... | CAS号203381-39-9 3,7-dimethyl-8-... | CAS号188568-13-0 acetic acid,7-(... | CAS号6753-98-6 α-石竹烯 | CAS号68-26-8 视黄醇 | CAS号2436-90-0 二氢月桂烯 | CAS号2492-22-0 2,6-二甲基-2-反式-6-辛二烯 | CAS号123-35-3 月桂烯

合成工艺路线路线简述

  • 合成目标产物 Geranyl Acetate 主要起始原料 Geraniol And Acetic Anhydride
  • (文献来源)合成步骤主要原料 Geraniol 和 Acetic Anhydride
芳樟醇置于吡啶,三溴化磷体系中,化学反应生成乙酸香叶酯
参考文献:Prevost,Annales De Chimie (Cachan,France),1928,Vol. <10>10,P. 178,179
标题:Prevost,Annales De Chimie (Cachan,France),1928,Vol. <10>10,P. 178,179

海关参考信息

专利信息


专利号:US-7247752-B2
优先权日:2004-10-01
标 题 :Methods for the synthesis of astaxanthin
发明人:LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID
权利人:CARDAX PHARMACEUTICALS INC
摘要:A method used for synthesizing intermediates for use in the synthesis of carotenoids and carotenoid analogs, and/or carotenoid derivatives. In some embodiments, the invention includes methods for synthesizing optically active intermediates useful for the synthesis of optically active carotenoids. Synthesis of optically active carotenoids, in one embodiment, may be accomplished by forming an optically active dihydroxy intermediate from ketoisopherone. The optically active dihydroxy intermediate may be converted into optically active astaxanthin derivatives.

专利号:WO-2009104605-A1
优先权日:2008-02-18
标 题 :Novel intermediate for synthesis of ascofranone having various physiological activities, and novel shortened total synthesis method for ascofranone using the same
发明人:SAIMOTO HIROYUKI; HAGA YASUSHI
权利人:ARIGEN PHARMACEUTICALS INC; SAIMOTO HIROYUKI; HAGA YASUSHI
摘要:In the synthesis of ascofranone, a compound represented by formula (III), (IV), (V) or (VII) or an optical isomer thereof is used as an intermediate for the synthesis. [In the formulae, R 1 and R 2 independently represent a hydrogen atom, a C 1-7 alkyl group, a phenoxyalkyl group having a halogen atom on a carbon atom in a benzene ring therein, or a phenyl group having a C 1-7 alkoxy group or a C 1-7 alkoxycarbonyl group on a carbon atom in a benzene ring therein; and X represents a halogen atom or a group R 5 SO 3 (wherein R 5 represents a C 1-7 alkyl group or a phenyl group having a C 1-7 alkyl group on a carbon atom in a benzene ring therein).] By using the compound, it becomes possible to reduce the number of steps required for the total synthesis of ascofranone to 7 or 8 from 12 which is a number of the steps required for the conventional ascofranone total synthesis processes.

专利号:US-2024240209-A1
优先权日:2021-04-20
标 题:Synthesis of enantiopure cis-a-irone from a renewable carbon source
发明人:CHEN XIXIAN; ZHANG CONGQIANG; T REHKA; SHUKAL SUDHA; SMITH DEREK; ANDRÉ ISABELLE; JEREMY ESQUE
权利人:AGENCY SCIENCE TECH & RES; INSTITUT NATIONAL DE RECH POUR L AGRICULTURE LALIMENTATION ET LENVIRONMENT; CENTRE NAT RECH SCIENT; INSTITUT NAT DES SCIENCES APPLIQUEES DE TOULOUSE
摘要:Synthesis of enantiopure cis-α-irone from a renewable carbon source Disclosed herein are natural and synthetic enzymes capable of performing a method of producing cis-α-irone. The method comprises providing an enzyme capable of converting psi-ionone to cis-α-irone; and contacting the enzyme and psi-ionone under suitable conditions to produce cis-α-irone. The enzyme may be a methyltransferase from Streptomyces albireticuli (SaMT), a promiscuous bifunctional methyltransferase/cyclase (pMT1) enzyme from Streptomyces, or a modified pMT1 enzyme with at least one substitution. The enzymes allow the in-vivo and in-vitro production of cis-α-irone including the use of glucose as feedstock for the biotransformation into cis-α-irone.

专利号:US-7435861-B2
优先权日:2005-04-29
标 题 :Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates
发明人:LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID
权利人:CARDAX PHARMACEUTICALS INC
摘要:A method for synthesizing intermediates for use in the synthesis of carotenoid synthetic intermediates, carotenoid analogs, and/or carotenoid derivatives. The carotenoid analog, derivative, or intermediate may be administered to a subject for the inhibition and/or amelioration of any disease that involves production of reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals. In some embodiments, the invention may include methods for synthesizing chemical compounds including an analog or derivative of a carotenoid. Carotenoid analogs or derivatives may include acyclic end groups. In some embodiments, a carotenoid analog or derivative may include at least one substituent. The substituent may enhance the solubility of the carotenoid analog or derivative such that the carotenoid analog or derivative at least partially dissolves in water.

专利号:US-2008221377-A1
优先权日:2006-06-16
标题 :Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates
发明人:LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID; BRAUN CRISTI L
权利人:LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID; BRAUN CRISTI L
摘要:A method for synthesizing intermediates for use in the synthesis of carotenoid synthetic intermediates, carotenoid analogs, and/or carotenoid derivatives. The carotenoid analog, derivative, or intermediate may be administered to a subject for the inhibition and/or amelioration of any disease that involves production of reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals. In some embodiments, the invention may include methods for synthesizing chemical compounds including an analog or derivative of a carotenoid. Carotenoid analogs or derivatives may include acyclic end groups. In some embodiments, a carotenoid analog or derivative may include at least one substituent. The substituent may enhance the solubility of the carotenoid analog or derivative such that the carotenoid analog or derivative at least partially dissolves in water.

专利号:WO-2024130393-A1
优先权日:2022-12-21
标 题 :Nanoparticle and method of synthesis thereof
发明人:MOSKOVCHENKO SVITLANA
权利人:MOSKOVCHENKO SVITLANA
摘要:The present technology relates to nanoparticles, compositions comprising said nanoparticles, and methods of synthesis of said nanoparticles; wherein the nanoparticles comprise a metal nanoparticle core, a first coating of amphiphilic molecules, and a second coating of essential oil, essential oil primary constituent, or both, which combine the antimicrobial properties of metal nanoparticles, amphiphilic molecules, and essential oil or essential oil primary constituents.
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主要参考文献


1: Celuppi LCM, Capelezzo AP, Cima LB, Zeferino RCF, Carniel TA, Zanetti M, de Mello JMM, Fiori MA, Riella HG. Microbiological, thermal and mechanical performance of cellulose acetate films with geranyl acetate. Int J Biol Macromol. 2023 Feb 15;228:517-527. doi: 10.1016/j.ijbiomac.2022.12.170. Epub 2022 Dec 20. 17(1):85. doi: 10.1186/s12934-018-0930-y.
3: Capelezzo AP, Celuppi LCM, Kuhn KZ, Sanaiotto O, Scapinello J, Zanetti M, Zeferino RCF, Müller LG, Fiori MA, Riella HG. Acute toxicity study of antibacterial organophilic bentonite incorporated with geranyl acetate in mice and geranyl acetate liberation in simulated gastric fluid. Toxicon. 2023 Mar 1;224:107027. doi: 10.1016/j.toxicon.2023.107027. Epub 2023 Jan 20. 42(6):3030-3050. doi: 10.1080/07391102.2023.2212060. Epub 2023 May 18.

合成参考文献


摘要:Schramm, M. P., Science of Synthesis, (2009) 46, 489.
摘要:Roy, K.-M., Science of Synthesis, (2010) 47, 1140.
摘要:Roy, K.-M., Science of Synthesis, (2010) 47, 1141.
摘要:Negishi, E.; Wang, G., Science of Synthesis, (2010) 47, 978.
摘要:Clark, R. W.; Wiskur, S. L., Science of Synthesis Knowledge Updates, (2015) 1, 30.
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