CAS: 1006873-58-0; Borane, 5-Ethyl-2-Methyl-Pyridine

英文名称Borane, 5-Ethyl-2-Methyl-Pyridine
中文名称5-乙基-2-甲基吡啶硼烷
CAS编号1006873-58-0
EINECS号:640-972-9
FDA UNII编号:9CF35452BU
分子式:C8H11N.BH3
分子量:135.01446
产品CID: 16182

相似结构搜索
InChIKey: VPEPQDBAIMZCGV-UHFFFAOYSA-N
1S/C8H11N.B/c1-3-8-5-4-7(2)9-6-8;/h4-6H,3H2,1-2H3;…
计算化学: 氢键受体数1.0氢键供体数0.0可旋转键数1.0

MSDS等安全信息

GHS象形图
GHS符号GHS06 & GHS05;
注释: Skull and crossbones & Corrosion
危险类别急性毒性类别3(吸入)
急性毒性类别3(经皮)
急性毒性类别4(经口)
皮肤腐蚀类别1B
严重眼损伤类别1
皮肤致敏类别1B
急性毒性类别1(吸入)
急性毒性类别3(经口)
皮肤腐蚀/刺激类别2
严重眼刺激类别2
警示词Danger(危险)
危险描述H331 |吸入会中毒.
H311 |皮肤接触会中毒.
H302 |吞咽有害.
H314 |造成严重皮肤灼伤和眼损伤.
H318 |造成严重眼损伤.
H317 |可能引起皮肤过敏反应.
H330 |吸入致命.
H301 |吞咽会中毒.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
防范说明P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P311-P321-P403+P233-P405-P501-P280-P305+P351+P338-P310-P260-P264-P280-P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P305+P351+P338-P405-P501-P280-P302+P352-P312-P322-P361-P363-P405-P501
危险品标志T+

欧盟法规

C&L通报

上下游产品

5-ethyl-2-methyl-pyridine

合成工艺路线路线简述

合成目标产物 5-Ethyl-2-Methylpyridine Borane 主要起始原料 5-Ethyl-2-Methylpyridine
(文献来源)合成步骤主要原料 5-Ethyl-2-Methylpyridine

专利信息

专利号:EP-3412666-A1
优先权日:2017-06-07
标题:Process and intermediates for the preparation of bcl-2 inhibitors including venetoclax through reductive amination
发明人：GREGG BRIAN THOMAS; GEISS WILLIAM BERT; HERR ROBERT JASON
权利人:ALBANY MOLECULAR RES INC
摘要:The invention relates to a process for the preparation of compounds of formula (I), which are useful intermediates in the synthesis of Venetoclax and structurally related compounds, by reductive amination of a compound of formula (II).

专利号:US-8106200-B2
优先权日:2006-09-21
标题 :Pyridine borane complexes
发明人：BURKHARDT ELIZABETH
权利人:BURKHARDT ELIZABETH; BASF SE
摘要:The present invention relates to new borane complexes with substituted pyridines, a process for the synthesis of new borane complexes with substituted pyridines, solutions comprising new borane complexes with substituted pyridines and a method of using new borane complexes with substituted pyridines for organic reactions.

专利号:US-9133188-B2
优先权日:2011-05-12
标题:Methods for preparing naphthyridines
发明人：PAUL DHARAM; HARVEY ANDREW JOHN; FLYNN BERNARD LUKE
权利人:PAUL DHARAM; HARVEY ANDREW JOHN; FLYNN BERNARD LUKE; BIONOMICS LTD
摘要:The present invention provides methods of synthesizing compounds of formula (1) and intermediates thereto. The present invention also provides intermediates useful in the synthesis of compounds of formula (1).

专利号:EP-4086245-A1
优先权日:2018-01-30
标题 :Processes for preparing intermediates for the synthesis of a jak inhibitor