CAS: 886761-59-7; 2-Chloro-6-Fluoro-3-Methoxybenzonitrile
该化合物是氟化和氯化的苯并呋喃衍生物,在3号位置具有一种甲氧替代物,该化合物是有机合成的多用途中间体,特别是在发展农用化学和药品方面,其独特的替代模式在交叉反应,核生殖替代和其他变异方面增强回弹性.电离层(氟,氯,硝基)和电饱和(甲基氧)组的存在,都允许选择性的功能化,对构建复杂的乙型循环或活性成分很有价值.高纯度能能确保研究和工业应用的一贯性能.由于潜在的再活动危险,建议适当处理.
物理性质
MSDS等安全信息
合成工艺路线路线简述
海关参考信息
- 2902300000-甲苯
2903919090-氯苯
2905110000-甲醇
2908199090-其他酚的卤化衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-7196090-B2
优先权日:2002-07-25
标题 :Kinase inhibitors
发明人：CONNOLLY CLEO J CHIVIKAS; DEUR CHRISTOPHER JAMES; HAMBY JAMES MARINO; HOYER DENTON WADE; LIMBERAKIS CHRIS; REED JESSICA ELIZABETH; SCHROEDER MEL CONRAD; TAYLOR CLARKE
权利人:WARNER LAMBERT CO
摘要:This invention provides phenyl-substituted pyrimidopyrimidines, dihydropyrimido-pyrimidines, pyridopyrimidines, naphthyridines, and pyridopyrazines of the general formula: n nthat inhibit cyclin-dependent kinase and tyrosine kinase enzymes, methods and intermediate compounds for their synthesis, as well as pharmaceutical compositions and methods for their use in treating, inhibiting or preventing maladies associated with cell proliferative disorders, including angiogenesis, atherosclerosis, restenosis, and cancer.
