CAS: 68-41-7; (R)-4-Aminoisoxazolidin-3-One

相似化合物

68-39-3 339-72-0 339-72-0

上下游产品

3-chloro-D-alanine hydroxyamide N-benzyloxycarbonyl-O-(toluene-4-sulfonyl)-D-serine benzyloxyamideN-benzyloxycarbonyl-O-(toluene-4-sulfonyl)-D-serine benzyloxyamide R)-4-benzyloxycarbonylamino-3-oxo-isoxazolidine-2-carboxylic acid benzyl ester(R)-4-benzyloxycarbonylamino-3-oxo-isoxazolidine-2-carboxylic acid benzyl ester tert-butyl N-[(4R)-3-oxoisoxazolidin-4-yl]carbamateR)-3-acetoxy-4-acetylamino-4,5-dihydro-isoxazole(R)-3-acetoxy-4-acetylamino-4,5-dihydro-isoxazole N-acetyl-D-cycloserine (3R,6R)-3,6-bis[(aminooxy)methyl]piperazine-2,5-dione R)-4-benzyloxycarbonylamino-3-oxo-isoxazolidine-2-carboxylic acid benzyl ester(R)-4-benzyloxycarbonylamino-3-oxo-isoxazolidine-2-carboxylic acid benzyl ester

Methyl (2R)-2-Amino-3-(Aminooxy)Propanoate置于sodium Hydroxide,溶剂黄146体系中,用 水,异丙醇 作为反应溶剂,化学反应 4.0H,以80%的收率获得产物d-环丝氨酸
参考文献:有效且简便地合成基本不含潜在杂质的d-环丝氨酸
标题:有效且简便地合成基本不含潜在杂质的d-环丝氨酸
摘要:已经从d-丝氨酸开发了一种有效且容易的d-环丝氨酸合成方法,采用保护脱保护策略,总收率达61%.研究了影响d-环丝氨酸杂质含量和产率的不同参数.温和的反应条件为产品提供了卓越的纯度(> 99%)和高稳定性.
DOI:10.1007/s10593-018-2197-Y

专利信息

专利号:US-9353057-B2
优先权日:2003-12-30
标 题:Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
发明人：GALLOP MARK A; DAI XUEDONG; SCHEUERMAN RANDALL A; RAILLARD STEPHEN P; MANTHATI SURESH K; YAO FENMEI; PHAN THU; LUDWIKOW MARIA; PENG GE; BHAT SEEMA
权利人:XENOPORT INC
摘要:Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine-containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful intermediates in the synthesis of 1-(acyloxy)-alkyl carbamates are also described.

专利号:US-7323575-B2
优先权日:2003-04-09
标题:Process for the synthesis of (2S)-indoline-2-carboxylic acid
发明人：SOUVIE JEAN-CLAUDE; LECOUVE JEAN-PIERRE
权利人:SERVIER LAB
摘要:Process for the synthesis of (2S)-indoline-2-carboxylic acid of formula (I): n nApplication in the synthesis of perindopril and its pharmaceutically acceptable salts.

专利号:US-2024197774-A1
优先权日:2021-04-16
标 题:Synthesis of Antimicrobial PVP-coated Bismuth Nanoparticles
发明人：LOPEZ-RIBOT JOSE; VAZQUEZ-MUNOZ ROBERTO
权利人:UNIV TEXAS
摘要:Described herein is a facile, fast, and economical method for the synthesis of BAL-mediated PVP-BiNPs, using basic laboratory instruments and reagents readily available in most laboratories.

专利号:US-9255255-B2
优先权日:2013-03-04
标 题 :Synthesis of linear and branched polymers of polypeptides through direct conjugation
发明人：ALBAYRAK CEM; SWARTZ JAMES R; LU YUAN
权利人:UNIV LELAND STANFORD JUNIOR
摘要:Methods are provided for a one step synthesis of polypeptide polymers or co-polymers. The polymers or co-polymers can be linear or branched. In the methods of the invention, the coding sequence for the polypeptide(s) to be polymerized is altered by introducing one or more codons for an nonnatural amino acid, which coding sequence is then utilized to produce the cognate polypeptide. The nonnatural amino acids are selected to be reactive with each other in a bioorthogonal reaction, and are combined in a conjugation reaction with the desired components of the polymer.

专利号:US-9315483-B2
优先权日:2007-09-13
标题 :Synthesis of deuterated catechols and benzo[D][1,3]dioxoles and derivatives thereof
发明人：JONES ANDREW D; ZELLE ROBERT E; SILVERMAN I ROBERT
权利人:CONCERT PHARMACEUTICALS INC
摘要:The present invention provides a convenient and efficient process for the synthesis of d 2 -benzo[d][1,3]dioxoles.

专利号:US-2011087037-A1
优先权日:2007-10-31
标题:Synthesis of ring b abeo-sterols as novel inhibitors of mycobacterium tuberculosis
发明人：RODRIGUEZ-PIERLUISSI ABIMAEL D; WEI XIAOMEI
权利人:INTELLECTUAL PROPERTY AND TECHNOLOGY VIC OFF OF
摘要:Novel 3β-hydroxy-Δ 5 -steroid analogs possessing a contracted cyclopentane B-ring provide good inhibitory activity against Mycobacterium tuberculosis . The 5(6→7)abeo-sterol nucleus present in compounds of the invention represents a novel scaffold for the development of new antitubercular agents.