CAS: 5437-45-6; Benzyl 2-Bromoacetate

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CAS号79-08-3 溴乙酸 | CAS号100-51-6 苯甲醇 | CAS号598-21-0 溴乙酰溴 | CAS号96-32-2 溴乙酸甲酯 | CAS号18942-89-7 1-acetoxy-2-nit... | CAS号28328-54-3 3-氨基-5-(氨基磺酰基)-... | CAS号105-36-2 溴乙酸乙酯 | CAS号13837-45-1 1-乙氧基-1-环丙醇 | CAS号103-50-4 二苄醚 | CAS号5396-89-4 乙酰丙酮苄酯 | CAS号57443-18-2 二甲基膦酸乙酸苄酯 | CAS号756-79-6 甲基膦酸二甲酯 | CAS号143023-95-4 benzyl 2-(2-oxo... | CAS号140-11-4 乙酸苄酯 | CAS号272120-41-9 (4,7,10-TRIS-BE... | CAS号30379-54-5 2-(苄氧基)乙酸苄酯 | CAS号78385-36-1 (苄氧羰基甲基)三苯基溴化膦 | CAS号87460-09-1 苄基羟基(4-苯基丁基)膦基乙酸酯 | CAS号103-41-3 肉桂酸苄酯

Benzyl 2-(Tributylstannyl)Acetate置于tetrabutylammonium Hexanitratocerate(Iv),四溴化碳,Potassium Carbonate体系中,用 乙腈 作为反应溶剂,化学反应 2.0H,以68%的收率获得产物2-溴乙酸苄酯
参考文献:α-甲锡烷基衍生物氧化反应生成羰基化合物的α-自由基及其与富电子烯烃的反应
标题:α-甲锡烷基衍生物氧化反应生成羰基化合物的α-自由基及其与富电子烯烃的反应
摘要:用四丁基六硝酸铵 (Iv) 氧化 α-三丁基链烷酸甲烷基酯,通过消除锡鎓离子产生链烷酸酯的 α-自由基.由此形成的自由基与各种富含电子的烯烃化合物(例如甲硅烷基烯醇醚)反应,以非常好的收率获得产物加成产物.该方法正式实现了链烷酸酯和酮之间的选择性交叉偶联.
DOI:10.1246/bcsj.68.322

专利信息

专利号:US-6683189-B1
优先权日:1996-02-26
标 题 :Method for the synthesis of pyrrole and imidazole carboxamides on a solid support
发明人：DERVAN PETER B; BAIRD ELDON
权利人:CALIFORNIA INST OF TECHN
摘要:The present invention describes a novel method for the solid phase synthesis of polyamides containing imidazole and pyrrole carboxamides. The polyamides are prepared on a solid support from aromatic carboxylic acids and aromatic amines with high stepwise coupling yields (>99%), providing milligram quantities of highly pure polyamides. The present invention also describes the synthesis of analogs of the natural products Netropsin and Distamycin A, two antiviral antibiotics. The present invention also describes a novel method for the solid phase synthesis of imidazole and pyrrole carboxamide polyamide-oligonucleotide conjugates. This methodology will greatly increase both the complexity and quantity of minor-groove binding polyamides and minor-groove binding polyamide-oligonucleotide conjugates which can be synthesized and tested.

专利号:US-10189803-B2
优先权日:2008-02-22
标题 :Synthesis of therapeutic and diagnostic drugs centered on regioselective and stereoselective ring opening of aziridinium ions
发明人：CHONG HYUN-SOON
权利人:CHONG HYUN SOON; ILLINOIS INSTITUTE OF TECH
摘要:Stereoselective and regioselective synthesis of compounds via nucleophilic ring opening reactions of aziridinium ions for use in stereoselective and regioselective synthesis of therapeutic and diagnostic compounds.

专利号:WO-0058264-A1
优先权日:1999-03-26
标 题:Method for the synthesis of non-symmetrical dtpa compounds
发明人：ACHILEFU SAMUEL I; SRINIVASAN ANANTHACHARI
权利人:MALLINCKRODT INC; ACHILEFU SAMUEL I; SRINIVASAN ANANTHACHARI
摘要:The synthesis of compounds of formula (XIV) wherein each R4 is an alkyl group having 1 to 15 carbon atoms, and R6 is a linking moiety having 1 to 10 carbon atoms, is disclosed. These compounds are useful intermediates in the synthesis of compounds of formula (X). These compounds are useful in the preparation of nuclear pharmaceuticals such as those used for tumor imaging or tumor therapy.

专利号:WO-0102339-A1
优先权日:1999-07-01
标题 :Versatile method for the synthesis of iso-dtpa
发明人：ACHILEFU SAMUEL I
权利人:MALLINCKRODT INC; ACHILEFU SAMUEL I
摘要:The synthesis of compounds of formula (XII) is disclosed. These compounds are useful intermediates in the synthesis of compounds of formulae (XI) and (X). These compounds are useful in the preparation of nuclear pharmaceuticals such as those used for tumor imaging or tumor therapy.

专利号:WO-0058267-A1
优先权日:1999-03-26
标 题 :Enhanced selectivity in the synthesis of dtpa esters fom diethylenetriamine
发明人：ACHILEFU SAMUEL I
权利人:MALLINCKRODT INC; SRINIVASAN ANANTHACHARI; ACHILEFU SAMUEL I
摘要:The synthesis of compounds of formula (XI) is disclosed. These compounds are useful intermediates in the synthesis of compounds of formula (X). These compounds are useful in the preparation of nuclear pharmaceuticals such as those used for tumor imaging or tumor therapy.

专利号:EP-1085020-B1
优先权日:1999-09-17
标题 :Synthesis of peptide nucleic acids
发明人：BATZ HANS-GEORG; HANSEN HENRIK FRYDENLUND; OERUM HENRIK; KOCH TROELS; KOFOED THOMAS
权利人:PNA DIAGNOSTICS APS APPLIED BI
摘要:Protected diaminopurines can be used in the synthesis of nucleic acid binding compounds containing diaminepurine in place of other nucleobases. A method for the synthesis of protected diaminopurines is disclosed which is convenient for incorporating modified diaminopurines into monomers or into oligomers for the preparation of nucleic acid binding compounds.