CAS: 4731-65-1; Tris(2-Methoxyphenyl)Phosphine

上下游产品

4-methoxyphenyl magnesium bromide methoxybenzene 2-methoxyphenyllithium 2-bromoanisolebis(2-methoxyphenyl)phosphine (4R,5R)-4,5-Bis-{[bis-(2-methoxy-phenyl)-phosphanyl]-methyl}-2,2-dimethyl-[1,3]dioxolane tris(2-hydroxyphenyl) phosphine oxide tert-butyl (E)-3-[4-(1-{4-[(E)-3-(tert-butoxy)-3-oxo-1-propenyl]phenyl}-1H-pyrrol-2-yl)phenyl]-2-propenoate

2-溴苯甲醚置于magnesium,三氯化磷体系中,用 四氢呋喃 作为反应溶剂,化学反应生成 三(2-甲氧基苯基)膦
参考文献:Synthesis,Structure,And Ethylene Polymerization Behavior Of Nickel Complexes Based On Benzoylmethylenetri(2-Alkoxylphenyl)Phosphorane
标题:Synthesis,Structure,And Ethylene Polymerization Behavior Of Nickel Complexes Based On Benzoylmethylenetri(2-Alkoxylphenyl)Phosphorane
摘要:在 Pph3 的存在下,通过用 Ni(Cod)2 处理稳定的苯甲酰亚甲基三(2-烷氧基苯基)磷烷,制备出了几种新的镍络合物.x 射线衍射研究表明,Ni(II) 周围的几何形状为扭曲的正方形.经 Ni(Cod)2 处理后,镍络合物对乙烯聚合具有足够的稳定性.磷上 2-烷氧基芳基取代基的存在提高了催化活性.当使用三(2-异丙氧基苯基)磷烷(5E)时,活性最高(2.1 x 106 G Mol-1 H-1),比相应的 Shop 催化剂高一个数量级.核磁共振分析表明,聚乙烯主要含有末端双键,具有很高的线性.
DOI:10.1039/c2Dt12052F

专利信息

专利号:US-2023286918-A1
优先权日:2020-07-02
标 题:Manufacturing process for 3,5-dichloropicolinonitrile for synthesis of vadadustat
发明人：JURKAUSKAS VALDAS; JUNG YOUNG CHUN; KWON TAESOO; KANNAN ARUNACHALAM; GONDI VIJAYA BHASKER
权利人:AKEBIA THERAPEUTICS INC
摘要:Disclosed herein are methods and processes of preparing vadadustat or a pharmaceutically acceptable salts thereof, and intermediates (e.g., a compound of Formula (I), (I-F), (II), or (IV), or a pharmaceutically acceptable salts thereof) useful for the synthesis of vadadustat.

专利号:US-4985567-A
优先权日:1988-03-07
标题:Chiral phosphinopyrrolidine compounds and their use for asymmetric synthesis of optically active compounds
发明人：ACHIWA KAZUO; TAKEDA HIDEO
权利人:KAZUO ACHIWA; FUJI YAKUHIN KOGYO KK
摘要:New chiral phosphinopyrrolidine compounds of the general formula: ##STR1## wherein R 1 is hydrogen or --COA 1 , --COOA 2 , --CONHA 3 , --SO 2 A 4 or --PO(A 5 ) 2 , A 1 , A 2 , A 3 , A 4 and A 5 each represents independently alkyl or aryl, R 2 is phenyl, di(lower-alkyl)aminophenyl, lower-alkoxyphenyl or 3,5-dimethyl-4-methoxyphenyl, and R 3 is phenyl, lower-alkylphenyl, di(lower-alkyl)aminophenyl, lower-alkoxyphenyl or 3,5-dimethyl-4-methoxyphenyl, with the proviso that R 2 and R 3 may not simultaneously by phenyl, p-di(lower-alkyl)-aminophenyl or p-lower-alkoxyphenyl, as well as the use of these compounds as ligand for a metal complex catalyst for asymmetric synthesis of optically active compounds. The new chiral phosphinopyrrolidine compounds are useful ligands which attain both of high optical yield and high reaction efficiency in catalytic asymmetric reduction.

专利号:US-5446225-A
优先权日:1992-02-05
标题:Palladium catalyzed akylative cyclization useful in syntheses of Vitamin D and analogues
发明人：TROST BARRY M; DUMAS JACQUES
权利人:UNIV LELAND STANFORD JUNIOR
摘要:An alkylative cycloaddition method is provided that is particularly useful for the synthesis of many of the Vitamin D analogues with differing side chains. Thus, a preferred synthesis is of Vitamin D analogues having a side chain R 1 where a first precursor having the structure ##STR1## with X being a halide or a pseudo halide, and a second precursor are provided, the second precursor being a 1,7 enyne. These precursors are reacted in the presence of a palladium catalyst to form compounds having the structure ##STR2## where R 2 is hydrogen, hydroxyl, lower alkoxy, fluorine, or a protecting group, and R 3 is hydrogen, hydroxyl, lower alkoxy, fluorine, or a protecting group.

专利号:US-9718807-B2
优先权日:2012-06-05
标 题 :Synthesis of antiviral compound
发明人：SCOTT ROBERT WILLIAM; VITALE JUSTIN PHILIP; MATTHEWS KENNETH STANLEY; TERESK MARTIN GERALD; FORMELLA ALEXANDRA; EVANS JARED WAYNE
权利人:GILEAD PHARMASSET LLC
摘要:The present disclosure provides processes for the preparation of a compound of formula I: n nwhich is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates to compounds of formula I.

专利号:US-7217842-B2
优先权日:2001-04-12
标题:Catalysts for nucleophilic substitution, synthesis thereof, composition containing them and use thereof
发明人：SCHANEN VINCENT; CRISTAU HENRI-JEAN; TAILLEFER MARC
权利人:RHONE POULENC CHIMIE
摘要:The invention concerns novel catalysts for aromatic nucleophilic substitution. Said catalysts are compounds of the general formula (I), wherein: R 1 , R 2 , R 3 , R 4 , R 5 , and R 6 , identical or different, are selected among hydrocarbon radicals; the Pn's, advantageously the same, are selected among metalloid elements of column V of a period higher than nitrogen; Z is a metalloid element of column V, advantageously distinct from Pn; preferably a nitrogen (N, P, As, Sb). The invention is applicable to organic synthesis

专利号:US-9834536-B2
优先权日:2013-04-23
标题:Method for producing catalyst for cyclic carbonate synthesis
发明人：TAKAHASHI TOSHIKAZU; YASUDA HIROYUKI; SAKAKURA TOSHIYASU; YAMAMOTO SHOUJI; NANIKI TAKASHI; FURUKAWA TAKURO
权利人:AIST; MARUZEN PETROCHEM CO LTD
摘要:A method for producing a heterogeneous catalyst for use of synthesizing cyclic carbonates by reacting an epoxide and carbon dioxide in the presence of the catalyst. A method for making a catalyst that includes forming a catalyst precursor then reacting the catalyst precursor with a tertiary phosphine.