CAS: 420-56-4; Fluoro(Trimethyl)Silane

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CAS号75-77-4 三甲基氯硅烷 | CAS号73390-32-6 [(bzq)Pd(OAc)]2 | CAS号107-46-0 六甲基二硅氧烷 | CAS号677-67-8 2-(氟磺酰基)二氟乙酰基氟化物 | CAS号27607-77-8 三氟甲磺酸三甲基硅酯 | CAS号18292-28-9 but-2-enyl(trim... | CAS号762-72-1 烯丙基三甲基硅烷 | CAS号18292-38-1 异丁烯基三甲基硅烷 | CAS号59201-86-4 TASF(Et) | CAS号10132-71-5 Ethylfluorodime... | CAS号1825-61-2 甲氧基三甲基硅烷 | CAS号373-74-0 甲基三氟硅烷 | CAS号271772-12-4 fluorodimethoxy... | CAS号271772-13-5 difluoro(methox... | CAS号353-66-2 二氟二甲基硅烷 | CAS号2083-91-2 N-(三甲基硅烷基)二甲胺 | CAS号661-62-1 (Dimethylamino)... | CAS号1066-40-6 三甲基硅醇 | CAS号51202-29-0 (trimethylsilyl...

📜六甲基二硅氧烷置于bf3*dioxan体系中,用 氘代苯 作为反应溶剂,化学反应生成 三甲基氟硅烷
参考文献:Zur Synthese Von Siloxanen:十一.spaltung Von Siloxanen Durch硼三氟
标题:Zur Synthese Von Siloxanen:十一.spaltung Von Siloxanen Durch硼三氟
摘要:通过1 H NMR光谱动力学研究了bf 3对硅氧烷键的裂解.当使用足够过量的bf 3时,可以通过使用伪一级速率定律评估反应.发现相对于bf 3的顺序为4.7.所得到的速率常数可以被关联到σ *-值与ρ *-1.0-值.确认了先前通过29 Si NMR光谱法测得的me 3 Sio基为0.35的σ *值.
DOI:10.1016/0022-328X(88)80636-3

专利信息

专利号:EP-0364340-B1
优先权日:1988-10-05
标题:Method for the synthesis of sulfonyl imides
摘要:Method for the synthesis of sulfonylimidides having the formula M((RSO2)2N)y, whrein M is a metal or an ammonium radical quaternary or not, the Rs, which may be identical or similar are organic monovalent radicals, particularly hydrocarbyles and preferably perfluorohydrocarbyles, in C1 to C12, and y is the valence of M. On the one hand, a silazane component selected amongst the silazane compounds M(((R2)3Si)2N)y or the associations of a silazane derivative A((R2)3Si)2N or a fluoride M1Fz of low cross-linking energy is reacted with, on the other hand, at least one sulfonic halogenite component consisting of a sulfonyl fluoride RSO2F or in the association of a sulfonyl chloride RSO2Cl with a fluoride M1Fz, M, R and y having the above-mentionned significations, M1 being selected amongst the Ms and being optionally identical to M, z being the valence of M1 and R2 representing an alkyl in C1 to C4. The imidides obtained for which the R2 are perfluorated radicals and M is an alkaline metal such as Li are usable in association with polyethers for the production of materials of the ionic conduction type for all solid generators in thin films.

专利号:US-10597340-B2
优先权日:2013-05-10
标 题:Synthesis of fluorinated radiopharmaceuticals via electrochemical fluorination
发明人：SADEGHI SAMAN; HE QINGGANG; LEBEDEV ARTEM
权利人:UNIV CALIFORNIA
摘要:Provided herein are methods and compositions for the electrochemical selective radiofluorination of aromatic molecules. The resulting fluorine-18 labeled compounds are ideal radionuclides for use in Positron Emission Tomography (PET); they are also difficult to radiolabel efficiently and with high specific activity using existing approaches. For example, radiopharmaceuticals such as [F18]L-DOPA, which is indispensable in PET brain disease imaging, may be made electrochemically with high radiochemical yield and high specific activity using 18F-. The invention process described herein opens new possibilities and provides wider access to PET tracers such as 18F-L-Dopa, since 18F- is much more widely available than the 18F 2 , currently used for synthesis of electron rich substrates.

专利号:US-2004014168-A1
优先权日:1998-06-11
标题:Reagents and methods for library synthesis and screening
发明人：SCHREIBER STUART L; BLACKWELL HELEN E; PEREZ FERNANDEZ LUCY; TALLARICO JOHN A
权利人:HUGHES HOWARD MED INST
摘要:The invention provides novel solid supports for the synthesis of compound libraries. The solid supports have the physical capacity to deliver at least 50 nmol of compound and are functionalized with a silicon-containing linker. In one embodiment of the invention the solid support comprises a bead having a diameter of between approximately 400 and 600 μm functionalized with a silicon-containing linker. According to certain embodiments of the invention the bead is a polystyrene bead. According to certain embodiments of the invention the linker is a diisopropylalkyl-substituted silyl ether. The invention further provides grafted polymeric supports such as lanterns functionalized with a silicon-containing linker. n The invention provides methods for screening in which compounds are synthesized on solid supports in a quantity so that a single solid support such as a bead provides a stock solution sufficient to perform hundreds or thousands of biological or chemical assays. The methods include decoding the sequence of chemical reactions used to synthesize the compound by identifying tags incorporated into the compound during synthesis.

专利号:US-2008221303-A1
优先权日:2004-02-18
标 题:Method for the Preparation of Peptide-Oligonucleotide Conjugates
发明人：KATZHENDLER JEHOSHUA; KLAUZNER YAKIR; BEYLIS IRENA; MIZHIRITSKII MICHAEL; SHPERNAT YAACOV; ASHKENAZI BORIS; FRIDLAND DMITRI
权利人:KATZHENDLER JEHOSHUA; KLAUZNER YAKIR; BEYLIS IRENA; MIZHIRITSKII MICHAEL; SHPERNAT YAACOV; ASHKENAZI BORIS; FRIDLAND DMITRI
摘要:The present invention relates to the synthesis of peptide-oligonucleotide conjugates (POC). More specifically, the invention relates to a novel method for the preparation of peptide-oligonucleotide conjugates, which can be conducted under mild conditions on solid support, can be performed manually or by a synthesizer, can be used to synthesize alternating sequences of peptides and oligonucleotides, and is applicable to the synthesis of a wide variety of peptide-oligonucleotide conjugates constructed from alternate peptide and oligonucleotide blocks.

专利号:US-5194562-A
优先权日:1989-02-22
标题:Nucleophilic displacement method for synthesis of non-rigid PBZ polymers
发明人：INBASEKARAN MUTHIAH N; MULLINS MICHAEL J
权利人:DOW CHEMICAL CO
摘要:Azole rings, such as oxazole and thiazole rings, can activate an aromatic ring bonded to a leaving group such as a halogen atom so that the aromatic ring will undergo aromatic nucleophilic substitution. The reaction is useful for making ethers, thioethers and amines containing azole rings. In particular, monomers having azole rings, activated aromatic rings with leaving groups and nucleophilic moieties can react under conditions of aromatic nucleophilic displacement to form non-rigid rob PBZ polymers. The non-rigid rod PBZ polymers can be used to form molecular composites with rigid rod PBZ polymers which molecular composites are not substantially phase separated.

专利号:US-5216110-A
优先权日:1989-02-22
标题 :Monomers useful in nucleophilic displacement synthesis of polybenzazole polymers
发明人：INBASEKARAN MUTHIAH N; MULLINS MICHAEL J
权利人:DOW CHEMICAL CO
摘要:Azole rings, such as oxazole and thiazole rings, can activate an aromatic ring bonded to a leaving group such as a halogen atom so that the aromatic ring will undergo aromatic nucleophilic substitution. The reaction is useful for making ethers, thioethers and amines containing azole rings. In particular, monomers having azole rings, activated aromatic rings with leaving groups and nucleophilic moieties can react under conditions of aromatic nucleophilic displacement to form non-rigid rod PBZ polymers. The non-rigid rod PBZ polymers can be used to form molecular composites with rigid rod PBZ polymers which molecular composites are not substantially phase separated.