CAS: 2503-56-2; 7-Hydroxy-5-Methyl-1,3,4-Triazaindolizine

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CAS号141-97-9 乙酰乙酸乙酯 | CAS号61-82-5 3-氨基-1,2,4-三唑 | CAS号24415-66-5 7-氯-5-甲基-1,2,4-...

📜3-氨基-1,2,4-三氮唑,乙酰乙酸乙酯置于溶剂黄146体系中,化学反应 16.0H,反应生成7-羟基-5-甲基-1,3,4-三氮吲哚利嗪
参考文献:三唑并嘧啶类抗结核药物的合成及评价
标题:三唑并嘧啶类抗结核药物的合成及评价
摘要:我们鉴定出具有抗结核分枝杆菌活性的二取代三唑并嘧啶.对支架的三段进行合理检查,建立构效关系,以提高效力并保持非常好的理化性质.许多化合物对结核分枝杆菌表现出亚微摩尔活性,但对真核细胞没有细胞毒性.C5 处未取代的芳环和连接 C7 处末端芳族的二碳链是优选特征;C7 处存在 Nh 且 C2 处缺乏取代基对于效力至关重要.我们鉴定出在啮齿动物和人类肝微粒体中具有可接受的代谢稳定性的化合物.我们的研究结果表明,易于合成的三唑并嘧啶是一类有前途的有效抗结核药物,值得在我们寻找抗结核新药时进行进一步研究.
Doi:10.1016/j.Bmc.2017.05.030

专利信息

专利号:US-6159673-A
优先权日:1996-07-17
标 题:Oxonol compound, light-sensitive material and process for the synthesis of oxonol compound
发明人：NISHIGAKI JUNJI; DEGUCHI YASUAKI
权利人:FUJI PHOTO FILM CO LTD
摘要:An oxonol compound is represented by the following formula (I): in which Z is an atomic group that forms a cyclic amide ring; each of W1 and W2 independently is an atomic group that forms an acidic nucleus ring; and M is a cation. Other oxonol compounds, a light-sensitive material containing an oxonol compound and a process for the synthesis of an oxonol compound are also disclosed.

专利号:EP-1473330-B1
优先权日:1996-07-17
标题:Process for the synthesis of oxonol compound
发明人：NISHIGAKI JUNJI; DEGUCHI YASUAKI
权利人:FUJI PHOTO FILM CO LTD
摘要:An oxonol compound is represented by the following formula (I): in which each of Z, W<1> and W<2> independently is an atomic group that forms a heterocyclic ring; and M is a cation. A process for the synthesis of an oxonol compound is disclosed.

专利号:US-5558974-A
优先权日:1994-03-11
标题 :Photographic material containing a new type of hydrazide
发明人：LOCCUFIER JOHAN; ANDRIESSEN HIERONYMUS
权利人:AGFA GEVAERT NV
摘要:A new type of hydrazide compounds is disclosed corresponding to general formula (A): (A) the symbols of which are explained in the description. Examples of synthesis are given. Incorporation of these diacyl hydrazides into the silver halide emulsion layer(s) of a photographic material causes a significant increase in sensitivity.

专利号:EP-1473330-A1
优先权日:1996-07-17
标题:Process for the synthesis of oxonol compound

专利号:US-6960426-B2
优先权日:1997-02-24
标 题:Silver halide material for optical memory devices with luminescent reading and methods for the treatment thereof
发明人：LEVICH EUGENE B; MALKIN JACOB N; ALPEROVICH MARK A; SHAPIRO BORIS M
权利人:DATA INC D
摘要:This invention concerns a luminescent optical memory material and method of forming this material, including the encoding of information by a photographic process. The method involves the use of silver halide crystals of a defined size range, with the optional use of sensitizers, emulsion stabilizers, and other agents followed by the absorption of luminescent dyes on the developed silver particle to form a luminescent optical memory system. The method involves synthesis of a photographic emulsion with silver halide crystals of a defined size range, applying photographic emulsion to a substrate, exposing to light photochemical treatment and a process of transformation of the silver particles formed in the places exposed by light into luminescent particles. The method involves obtaining a multi-layer luminescent material for a three-dimensional optical memory devices.

专利号:EP-0819977-A1
优先权日:1996-07-17
标题 :Oxonol compound, silver halide photographic material and process for the synthesis of oxonol compound