CAS: 21968-17-2; N-Propan-2-Ylpropan-1-Amine

该化合物是一种有机化合物,其特征是其有矿功能组;其特征是带有与氮原子相连的异丙基组的丙胺脊椎;该结构具有某些物理和化学特性,例如室内温度时无色可粉黄液,具有典型的探明味;该化合物在水和有机溶剂中溶解,这在阿米斯中很常见;该化合物由于有矿物质组的存在,因而具有基本性,允许其作为质子接受化学反应.N-1(1-甲基乙基乙基)-1-丙胺可以参与各种有机反应,包括通缩和串联,使其在合成有机化学中有用.此外,该化合物在制药或农用化学品生产中可能具有各种用途,但在处理和储存时需要参考安全数据,因为氨酯可能是刺激剂,如果管理不当,则可能构成健康风险.

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CAS号106-94-5 溴代丙烷 | CAS号75-31-0 异丙胺 | CAS号107-10-8 丙胺 | CAS号67-64-1 丙酮 | CAS号123-38-6 丙醛 | CAS号5792-46-1 N,N-di(propan-2... | CAS号60021-89-8 N-propan-2-yl-N...

合成工艺路线路线简述

    📜N-(Isopropylidene)Allylamine置于镍体系中,100.0~150.0 °C,6.86 Mpa 条件下,反应生成N-异丙基丙胺
    参考文献:Preparation Of Ketimines And The Corresponding Secondary Amines
    标题:Preparation Of Ketimines And The Corresponding Secondary Amines
    摘要:
    Doi:10.1021/jo01372A010

    海关参考信息

    专利信息


    专利号:US-6815214-B2
    优先权日:2000-12-29
    标 题 :Pharmaceutical uses and synthesis of diketopiperazines
    发明人:BOYCE JIM P; HOWBERT J JEFFRY; TABONE JOHN C
    权利人:CELLTECH R & D INC
    摘要:The synthesis of novel diketopiperazines, their use in inhibiting cellular events such as those involving NFK-α, NFK-β and in the treatment of inflammation events, a combinatorial library of diverse diketopiperazines and process for their synthesis as a library and as individual compounds. In particular novel diketopiperazines are disclosed including their synthesis and use in cellular events such as activation of the transcription factor, nuclear factor, TNF-α, TNF-β and also apoptosis.

    专利号:WO-2013113319-A1
    优先权日:2012-01-31
    标题 :Process for the preparation of strontium ranelate, intermediate or hydrates thereof
    发明人:KOFTIS THEOCHARIS V; ROHIT RAVIKANT SONI; BHARAT BECHARBHAI BODA; DIPAKKUMAR NARSIBHAI BHUT; VIMALKUMAR SUBHIRBHAI PATEL
    权利人:PHARMATHEN SA; KOFTIS THEOCHARIS V; ROHIT RAVIKANT SONI; BHARAT BECHARBHAI BODA; DIPAKKUMAR NARSIBHAI BHUT; VIMALKUMAR SUBHIRBHAI PATEL
    摘要:The present invention relates to an improved process for the synthesis of strontium ranelate compound of formula I or its hydrates thereof. More particularly, the present invention relates to an economically viable and industrially feasible process for the preparation of strontium ranelate, intermediate or its hydrates thereof.

    专利号:US-11130764-B2
    优先权日:2017-02-17
    标题 :Analogs of vincamine and uses thereof
    发明人:HUIGENS III ROBERT WILLIAM; NORWOOD IV VERRILL M; LUESCH HENDRIK
    权利人:UNIV FLORIDA
    摘要:The present disclosure provides compounds of any one of Formulae (I′), (I), (IA), (II′), (II), (IIA), (IIIA), (III″), (III′), (III), (IIIA), (IV), (V′), (V), (VI), (VII), (VIII′), (VIII), (IX′), (IX), and (X). The compounds described herein may be useful in treating and/or preventing a broad range of diseases (e.g., proliferative disease (e.g., cancers (e.g., non-small cell lung cancer, or glioma), inflammatory diseases, autoimmune diseases), CNS disorder (e.g., drug addiction), metabolic disorder (e.g., diabetes), or infectious disease (e.g., bacterial infection or parasitic infection (e.g., malaria))). Also provided in the present disclosure are pharmaceutical compositions, methods of synthesis of a compound described herein, kits, methods, and uses including or using a compound described herein.

    专利号:US-7442840-B2
    优先权日:2004-02-17
    标 题 :Synthesis of severely sterically hindered amino-ether alcohols and diaminopolyalkenyl ethers using a high activity powder catalyst
    发明人:ELIA CHRISTINE NICOLE; SISKIN MICHAEL; KERBY MICHAEL CHARLES; BISHOP ADEANA RICHELLE; MOZELESKI EDMUND JOHN; MALEK ANDRZEJ
    权利人:EXXONMOBIL RES & ENG CO
    摘要:The present invention relates to a process for preparing severely sterically hindered secondary amine ether alcohols and diamine polyalkenyl ethers by reacting a primary amino compound with a polyalkenylether glycol in the presence of a high activity nickel powder hydrogenation catalyst which is marked by high conversion of reactants and increased selectivity to desired final product.

    专利号:US-7741487-B2
    优先权日:2004-08-26
    标题 :Method for producing quaterrylene-3,4:13, 14-tetracarboxy diimides by direct synthesis
    发明人:KOENEMANN MARTIN; BOEHM ARNO; BIDLINGMAIER HERMANN; RIEGER REINHOLD; BLASCHKA PETER; REICHELT HELMUT; KRIEGER MATTHIAS
    权利人:BASF AG
    摘要:A process for preparing quaterrylene-3,4:13,14-tetracarboximides of the general formula I n nin whichn nR, R′ are each independently hydrogen or optionally substituted C 1 -C 30 -alkyl, C 5 -C 8 -cycloalkyl or aryl or hetaryl;n nwhich comprises reacting a perylene-3,4-dicarboximide of the general formula IIan n nin the presence of a base-stable, high-boiling, organic solvent and of an alkali metal base or alkaline earth metal base, with a perylene-3,4-dicarboximide of the general formula IIbn n nin which X is hydrogen, bromine or chlorine.

    专利号:US-7375058-B2
    优先权日:2001-09-14
    标 题:Herbicidal mixtures based on 3-phenyluracils
    发明人:ZAGAR CYRILL; SIEVERNICH BERND; QUAKENBUSH LAURA; EVANS RICHARD R; LANDES MAX; NEWSOM LARRY J; ORTLIP CHARLES L; WITSCHEL MATTHIAS; LANDES ANDREAS
    权利人:BASF AG
    摘要:Herbidically active compositions, comprising: A) at least one phenyluracil compound of the formula (I); in which the variables R 1 -R 7 are as defined in the claims, and/or at least one of its agriculturally acceptable salts; and at least one further active compound, selected from B) herbicides of classes b1) to b15): b1) lipid biosynthesis inhibitors; b2) acetolactate synthase inhibitors (ALS inhibitors); b3) photosynthesis inhibitors; b4) protoporphyrinogen-IX oxidase inhibitors; b5) bleacher herbicides; b6) enolpyruvyl shikimate 3-phosphate synthase inhibitors (EPSP inhibitors); b7) glutamine synthetase inhibitors; b8) 7,8-dihydropteroate synthase inhibitors (DHP inhibitors); b9) mitose inhibitors; b10) inhibitors of the synthesis of very long chain fatty acids (VLCFA inhibitors); b11) cellulose biosynthesis inhibitors; b12) decoupler herbicides; b13) auxin herbicides; b14) auxin transport inhibitors; b15) other herbicides selected from the group consisting of benzoylprop, flamprop, flamprop-M, bromobutide, chlorflurenol, cinmethylin, methyldymron, etobenzanid, fosamine, metam, pyributicarb, oxaziclomefone, dazomet, triaziflam and methyl bromide; and safeners selected from: benoxacor, cloquintocet, cyometrinil, dichlormid, dicyclonon, dietholate, fenchlorazole, fenclorim, flurazole, fluxofenim, furilazole, isoxadifen, mefenpyr, mephenate, naplithalic anhydride, 2,2,5-trimethyl-3-(dichloroacetyl)-1,3-oxazolidine, 4-(dichloroacetyl)-1-oxa-4-azaspiro[4.5]decane and oxabetrinil, the agriculturally acceptable salts of the active compounds B and C and the agriculturally acceptable derivatives of the active compounds B and C, provided they have a carboxyl group

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    主要参考文献

    参考标题:Improved Synthesis Of Severely Sterically Hindered Amino-Ether Alcohols And Diaminopolyalkenyl Ethers Using A High Activity Powder Catalyst
    摘要:The Present Invention Relates To A Process For Preparing Severely Sterically Hindered Secondary Amine Ether Alcohols And Diamine Polyalkenyl Ethers By Reacting A Primary Amino Compound With A Polyalkenylether Glycol In The Presence Of A High Activity Nickel Powder Hydrogenation Catalyst Which Is Marked By High Conversion Of Reactants And Increased Selectivity To Desired Final Product.

    合成参考文献


    摘要:Sartori, G.; Maggi, R., Science of Synthesis, (2005) 18, 670.
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