CAS: 15658-35-2; 6,6'-Dithiodinicotinic Acid

相似化合物

2127-03-9 2127-10-8 259544-96-2

上下游产品

CAS号17624-07-6 6-巯基烟酸 | CAS号74470-34-1 6-疏基吡啶-3-羧酸甲酯

📜在 L-精氨酸体系中,用 Aq. Buffer 用作溶剂,化学反应生成6,6'-二硫二烟酸,
参考文献:基于 Gdiii 的自旋标记在通过零场分裂优化线宽减少的极限
标题:基于 Gdiii 的自旋标记在通过零场分裂优化线宽减少的极限
摘要:电子顺磁共振谱中非常窄的中心线和非常弱的零场分裂 (Zfs) 使 [gd Iii (No3Pic)] ([gd Iii (Tpatcn)]) 成为自旋标记开发的一个有吸引力的起点.为了在用能够实现生物共轭的取代基对其进行修饰时保留该母体复合物的窄线,发现在吡啶甲酸酯部分具有某种远程官能团作为取代基的烷基非常合适,因为 Zfs 保持弱,即使三重轴对称是破碎的.Zfs 太弱以至于超精细耦合和/或g-值变化显着决定了生物分子质子化时 Q 波段和更高场的线宽,这是标准情况,以及 W 波段和完全氘化环境中质子化复合物的更高场.显然,[ndse-{gd Iii (No3Pic)}],一种靶向肽中半胱氨酸的自旋标记,通过 Zfs 最小化处于线宽变窄的极限.标记反应具有高度化学选择性,并且应用于具有两个半胱氨酸单元的聚脯氨酸,在 7 oc 和 Ph 7.8 下不超过一分钟.随后的二硫化物加扰非常缓慢,因此
Doi:10.1021/acs.Inorgchem.2C03531

专利信息

专利号:WO-9607676-A1
优先权日:1994-09-06
标 题 :Polymeric resin for disulfide bond synthesis
发明人：CLARK BRIAN R; PAI MOHANDAS
权利人:EKAGEN CORP; CLARK BRIAN R; PAI MOHANDAS
摘要:Disulfide resin compositions in which, following disulfide-thiol interchange, each thiol moiety remains attached to the resin, such resins affect the formation of inter or intramolecular peptide or protein disulfide bonds.

专利号:US-2024132955-A1
优先权日:2021-03-30
标 题:Benign scar-forming cleavable linkers
发明人：LEE LINDA; NIKIFOROV THEO; LIMARDO ALEXANDER JOSEPH; REAMEY MAYA H; MENCHEN STEVEN; ALMOGY GILAD
权利人:ULTIMA GENOMICS INC
摘要:Provided herein are reagents, compositions, and methods for sequencing nucleic acids. Among the reagents disclosed are nucleotides labeled with cleavable linkers. Certain linkers are configured to undergo immolation reactions following cleavage, which can generate scars with enhanced properties for nucleic acid sequencing and synthesis. The present disclosure also provides reagents, compositions, and methods for capping scars generated through linker cleavage, which can alter scar properties, and in some cases can increase the rate and accuracy of nucleotide incorporations during polymerization.

专利号:US-2013142763-A1
优先权日:2010-10-27
标题 :Crosslinked cellulosic polymers
发明人：CARLSON WILLIAM B; PHELAN GREGORY D; SULLIVAN PHILIP A
权利人:CARLSON WILLIAM B; PHELAN GREGORY D; SULLIVAN PHILIP A; EMPIRE TECHNOLOGY DEV LLC
摘要:Crosslinked cellulosic polymers, crosslinked cellulosic polymer hydro-gels, and methods for their synthesis and use are described. The crosslinked cellulosic polymers include one or more cellulosic polymers and a one or more crosslinkers that crosslinks the one or more cellulosic polymers together. The crosslinking can be facilitated with a crosslinking agent capable of linking with a monomer the cellulosic polymer and crosslinking the cellulosic polymer intermoleculerly and/or intramolecularly. Crosslinked cellulosic polymers are well adapted for use in cell and tissue growth in vivo and in vitro. The crosslinked cellulose polymers may also be used as wound care devices.