CAS: 79467-22-4; Bipenamol

上下游产品

benzonitrile 1,2-bis(2-(hydroxymethyl)phenyl)disulfane benzimidic acid ethyl ester 2-((2-(hydroxymethyl)phenyl)thio)benzonitrile N-[2-(2-hydroxymethyl-phenylsulfanyl)-benzyl]-acetamide2-azido-N-[2-(2-hydroxymethyl-phenylsulfanyl)-benzyl]-acetamide N-[2-(2-hydroxymethyl-phenylsulfanyl)-benzyl]-propionamide3-azido-N-[2-(2-hydroxymethyl-phenylsulfanyl)-benzyl]-propionamide

📜苯甲腈置于lithium Aluminium Tetrahydride,Dichloro(Pentamethylcyclopentadienyl)Rhodium (Iii) Dimer,Copper(II) Acetate Monohydrate,乙酰氯,双三氟甲烷磺酰亚胺银盐体系中,用 四氢呋喃,1,2-二氯乙烷 作为反应溶剂,化学反应 12.17H,反应生成 必潘拉醇
参考文献:连续的 C-H 活化能够方便地传递多功能芳烃
标题:连续的 C-H 活化能够方便地传递多功能芳烃
摘要:从丰富的原料中模块化构建多功能芳烃是合成化学的不懈追求,加速了药物和材料的发现.在此,使用多功能亚胺酸酯的多重 C-H 活化策略,实现了密集功能化的含硫芳烃分子库的便捷传递,从而能够简明地构建生物活性分子,如双苯萘酚.
DOI:10.1039/d1Cc03243G

专利信息

专利号:WO-0140193-A1
优先权日:1999-12-03
标题:Method for the synthesis of pyrazolines
发明人：BOLDI ARMEN M
权利人:CHEMRX ADVANCED TECHNOLOGIES I; BOLDI ARMEN M
摘要:The present invention provides a method for the synthesis of compounds of Formula (I). Also claimed are novel intermediates and their methods of synthesis.

专利号:US-2002103381-A1
优先权日:2000-11-30
标 题 :Method for the synthesis of pyrazolines
发明人：BOLDI ARMEN M
摘要:The present invention provides a method for the synthesis of compounds of Formula I: n n n Also claimed are novel intermediates and their methods of synthesis.

专利号:WO-2024076306-A1
优先权日:2022-10-05
标题:Micro-flow synthesis of compounds and systems thereof
发明人：WU JIE; LIU CHENGUANG; WANG MU
权利人:NAT UNIV SINGAPORE
摘要:The present disclosure concerns a micro-flow system for synthesis of a compound, comprising a tubing reactor configured to flow a reactant within its lumen thereof, an actuator for regulating the flow of the reactant in the lumen and a heterogeneous catalyst in fluid communication with the lumen. The present disclosure also concerns a method of micro-flow synthesising a compound using the micro-flow system.

专利号:US-7576211-B2
优先权日:2004-09-30
标题 :Synthesis of thienopyridinone compounds and related intermediates
发明人：DHANOA DALE S; BECKER OREN; NOIMAN SILVIA; CHEN DONGLI; MARANTZ YAEL; SHACHAM SHARON; HEIFETZ ALEXANDER; INBAL BOAZ; BAR-HAIM SHAY; MOHANTY PRADYUMNA; LOBERA MERCEDES; WU LAURENCE
权利人:EPIX DELAWARE INC
摘要:The invention relates to 5-HT receptor agonists and partial agonists. Novel thienopyridinone compounds represented by Formula I, and synthesis and uses thereof for treating diseases mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include Alzheimer's disease, cognition disorders, irritable bowel syndrome, nausea, emesis, vomiting, prokinesia, gastroesophageal reflux disease, nonulcer dyspepsia, depression, anxiety, urinary incontinence, migraine, arrhythmia, atrial fibrillation, ischemic stroke, gastritis, gastric emptying disorders, feeding disorders, gastrointestinal disorders, constipation, erectile dysfunction, and respiratory depression. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included.

专利号:US-2006084805-A1
优先权日:2004-09-30
标题:Synthesis of thienopyridinone compounds and related intermediates

专利号:US-7982040-B2
优先权日:2004-05-17
标题 :Thienopyridinone compounds and methods of treatment
发明人：DHANOA DALE S; BECKER OREN; NOIMAN SILVIA; MOHANTY PRADYUMNA; CHEN DONGLI; LOBERA MERCEDES; WU LAURENCE; MARANTZ YAEL; INBAL BOAZ; HEIFETZ ALEXANDER; BAR-HAIM SHAY; SHACHAM SHARON
权利人:NANOTHERAPEUTICS INC
摘要:The invention relates to 5-HT receptor agonists and partial agonists. Novel thienopyridinone compounds represented by Formula I, and synthesis and uses thereof for treating diseases mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include Alzheimer's disease, cognition disorders, irritable bowel syndrome, nausea, emesis, vomiting, prokinesia, gastroesophageal reflux disease, nonulcer dyspepsia, depression, anxiety, urinary incontinence, migraine, arrhythmia, atrial fibrillation, ischemic stroke, gastritis, gastric emptying disorders, feeding disorders, gastrointestinal disorders, constipation, erectile dysfunction, and respiratory depression. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included.