CAS: 68005-71-0; (R)-3-Methyl-2-(4-Methylbenzenesulfonamido)Butanoic Acid

相似化合物

1149-26-4 13734-41-3 1685-33-2

上下游产品

(2S)-3-methyl-2-[[(4-methylphenyl)sulfonyl]amino]butanoic acid ethyl ester L-valine methanesulfonyl chloride (2S,3S)-N-para-toluenesulfonyl-3-methylaziridine-2-carboxylic acid(S)-(+)-N-tosylvaline chloride (S)-3-methyl-2-(N-methyl-N-tosylamino)butanoic acid N-(toluene-4-sulfonyl)-L-valine thiazol-2-ylamideN-(toluene-4-sulfonyl)-L-valine thiazol-2-ylamide tert-butyl 3-methyl-2-(4-methylphenylsulfonamido)butanoate

📜N-(P-Toluenesulfonyl)-α-Dehydrovaline置于c46H46Clp2Rus2(1+)*cl(1-) 氢气体系中,用 乙醇 作为反应溶剂,25.0 °C,721.87 Kpa 条件下,反应 24.0H,以99%的收率获得产物n-对甲苯磺酰基-D-缬氨酸
参考文献: Process For Making N-Sulfonated-Amino Acid Derivatives[fr] Procede De Fabrication De Derives D'Acides Amines N-Sulfones
标题: Process For Making N-Sulfonated-Amino Acid Derivatives[fr] Procede De Fabrication De Derives D'Acides Amines N-Sulfones

专利信息

专利号:US-7368568-B2
优先权日:2001-08-03
标 题 :Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for production and the use
发明人：WESTERMANN JURGEN; PLATZEK JOHANNES; PETROV ORLIN
权利人:BAYER SCHERING PHARMA AG
摘要:The invention relates to new protected 3,5-dihydroxy-2,2-dimethyl-valeroarnides for the synthesis of edothilones and derivatives and process for the production and the use of the new compounds for the production of epothilones or epothilone derivatives.

专利号:US-11524957-B2
优先权日:2018-04-02
标 题 :Process for the synthesis of 2-[(2S)-1-azabicyclo[2.2.2]oct-2-yl]-6-(3-methyl-1H-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3H)-one
发明人：ZHU LEI; BAILEY JOHN DANIEL; DURAK LANDON; WAETZIG JOSHUA DAVID; MIZUNO MASAHIRO; MAEDA KAZUHIRO; YASUMA TSUNEO; YAMAGUCHI HIROSHI; FUKUOKA KOICHIRO; AKIYAMA KAZUYUKI
权利人:TAKEDA PHARMACEUTICALS CO
摘要:The present invention provides processes and synthetic intermediates for the synthesis of 2-[(2S)-1-azabicyclo[2.2.2]oct-2-yl]-6-(3-methyl-1H-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4 {3H)-one or a salt, hydrate, or tautomer thereof, or any combination thereof, which are Cdc7 kinase inhibitors, and are useful for the treatment of disorders of cell proliferation, particularly cancer, and other disorders associated with Cdc7 activity.

专利号:US-6933385-B2
优先权日:2001-08-03
标题 :Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for the production and the use
发明人：WESTERMANN JURGEN; PLATZEK JOHANNES; PETROV ORLIN
权利人:SCHERING AG
摘要:The invention relates to new protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for the production and the use of the new compounds for the production of epothilones or epothilone derivatives.

专利号:US-2003158412-A1
优先权日:2001-08-03
标 题:Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for the production and the use

专利号:US-2005272731-A1
优先权日:2001-08-03
标 题 :Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for production and the use

专利号:US-2008161580-A1
优先权日:2001-08-03
标题:Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for the production and the use