CAS: 6575-13-9; 2,6-Dimethylbenzonitrile

上下游产品

CAS号583-70-0 2,4-二甲基溴苯 | CAS号68-12-2 N,N-二甲基甲酰胺 | CAS号576-22-7 2-溴间二甲苯 | CAS号151-50-8 氰化钾 | CAS号86364-02-5 (2,6-dimethylph... | CAS号557-19-7 氰化镍 | CAS号105-56-6 氰乙酸乙酯 | CAS号6781-98-2 2-氯间二甲苯 | CAS号35629-85-7 2,6-Dimethyl-be... | CAS号7677-24-9 三甲基氰硅烷 | CAS号108-38-3 间二甲苯 | CAS号632-46-2 2,6-二甲基苯甲酸 | CAS号74788-82-2 2,6-二甲基苄胺 | CAS号62285-58-9 2,6-二甲基苯甲醇 | CAS号1123-56-4 2,6-二甲基苯甲醛 | CAS号2142-76-9 2',6'-二甲基苯乙酮 | CAS号21900-37-8 2,6-二甲基苯甲酰氯 | CAS号55321-98-7 2,6-二甲基苯甲酰胺

2,6-二甲基苄胺置于n-甲基咪唑,氧气,Copper(Ll) Bromide体系中,用 二甲基亚砜 作为反应溶剂,化学反应 24.0H,以89%的收率获得产物2,6-二甲基苄氰
参考文献:Cubr 2 / N-甲基咪唑催化苄胺选择性好氧氧化为芳基腈
标题:Cubr 2 / N-甲基咪唑催化苄胺选择性好氧氧化为芳基腈
摘要:描述了一种方便有效的铜催化的伯胺有氧氧化为芳基腈的方法.使用cubr 2 / Nmi作为催化剂和o 2作为氧化剂,可以将各种苄基和烯丙基胺以高收率选择性地氧化为相应的腈.通过1 H NMR监测的氧化反应曲线揭示了反应路径的情况以及添加剂的作用.nmi的加入提高了反应速率并抑制了水解和脱氨基作用.
DOI:10.1016/j.Tet.2018.06.054

专利信息

专利号:US-6376649-B1
优先权日:1998-12-18
标题 :Methods for the synthesis of α- hydroxy-β-amino acid and amide derivatives
发明人：SEMPLE JOSEPH E; LEVY ODILE E
权利人:CORVAS INT INC
摘要:Methods for the synthesis of alpha-hydroxy-beta-amino acid and amide derivatives and alpha-ketoamide derivatives and novel derivatives made by these methods are provided. These methods involve reacting a N-terminally blocked (protected) aminoaldehyde with an isonitrile and a carboxylic acid to give an amino-alpha-acyloxy carboxamide. The acyloxy group may be removed to give the derivative. Alternatively the protecting group is removed and acyl shift occurs to give the derivative. These derivatives are useful in the synthesis of compounds such as peptidyl alpha-ketoamides and alpha-hydroxy-beta-carboxylic acid and amide derivatives. Certain of these compounds have been reported to have activity as inhibitors of proteases, such as serine proteases and cysteine proteases.

专利号:US-2002147331-A1
优先权日:2001-02-02
标题:Methods for synthesis of oligonucleotides
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH
摘要:The present invention is directed to improved methods and compositions for synthesis of oligonucleotides and other phosphorus-linked oligomers, without the need for phosphoryl protecting groups. The methods involve the reaction of nucleoside phosphoramidites with a support-bound oligomer having one or more unprotected phosphorus-containing internucleoside linkages in the presence of a neutralizing agent.

专利号:US-2017320908-A1
优先权日:2014-11-19
标题 :Solid phase synthesis of cyclic amino acid molecules
发明人：HICKEY JENNIFER L; MANCUSO JOHN; MARSAULT ERIC; ROUGHTON ANDREW L; TREDER ADAM P; TREMBLEY MARIE-CLAUDE J; YUDIN ANDREI K; ZARETSKY SERGE
权利人:ENCYCLE THERAPEUTICS; GOVERNING COUNCIL OF THE UNIV OF TORONTO; UNIV SHERBROOKE
摘要:The present invention relates to cyclic amino acid molecules and methods of preparing the same, and in particular the macrocyclization of amino acids or linear peptides bound to a solid support.

专利号:US-2014296354-A1
优先权日:2013-04-01
标题 :Synthesis of peptoid-based small molecular gelators from multiple component reactions
发明人：WANG GUIJUN; MANGUNURU HARI P R
权利人:WANG GUIJUN; MANGUNURU HARI P R; OLD DOMINION UNIV RES FOUND
摘要:Described herein are the one-pot synthesis and characterization of a library of low molecular weight peptoid compounds that are able to form gels at room temperature. The compounds are synthesized from biologically-based starting materials, are biocompatible, and are resistant to degradation by proteases and peptidases. The compounds and gels synthesized therefrom can be used in such applications as tissue engineering, drug delivery, separation of biomolecules, and stimulus-responsive advanced materials

专利号:US-7579427-B2
优先权日:2004-06-30
标 题 :Synthesis of poly(arylene)s copolymers containing pendant sulfonic acid groups bonded to naphthalene as proton exchange membrane materials
发明人：GAO YAN; GUIVER MICHAEL D; ROBERTSON GILLES P
权利人:CA NAT RESEARCH COUNCIL
摘要:A new series of wholly aromatic poly(arylene ether ether ketone ketone)s containing pendant sulfonic acid groups (SPAEEKK) were conveniently prepared by potassium carbonate mediated nucleophilic polycondensation reactions of inexpensive commercially available monomers: 1,3-bis(4-fluorobenzoyl)benzene (BFBB), sodium 6,7-dihydroxy-2-naphthalenesulfonate (DHNS), and 4,4′-biphenol or hydroquinone in N-methyl-2-pyrrolidone (NMP) at 170° C. FT-IR and NMR were used to characterize the structures and the sulfonate or sulfonic acid contents (SC) of the polymers. Flexible membrane films were obtained by casting N,N-dimethylacetamide (DMAc) solutions of copolymers. Membrane films in acid form were then obtained by treating the sodium form membrane films in 2 N sulfuric acid at room temperature. Glass transition temperatures (T g s) and decomposition temperatures (T d s) of SPAEEKKs in both sodium and acid forms were determined. Water uptake and swelling ratio values increased with SCs and temperatures. The proton conductivities of acid form membrane films increased with SC value and temperature and reached 5.6×10 −2 S/cm at 100° C. for SPAEEKK-100.

专利号:US-2006004177-A1
优先权日:2004-06-30
标 题:Synthesis of poly(arylene)s copolymers containing pendant sulfonic acid groups bonded to naphthalene as proton exchange membrane materials