CAS: 525-64-4; 2,7-Diamino-Fluorene

该化合物其结构特征为该化合物其结构特征为:2,7,2和7个位置的荧光柱上附着两个氨基组(-NH2),该化合物是氟乙烯,多环芳烃的衍生物,并展示了氨胺和芳香化合物的典型特性,一般是室温固态,可能看起来像一种黄色至橙色晶体物质. 2,7-Diaminofluene,因其在有机合成中的潜在应用而著名,特别是在染料,色料和较复杂的有机分子的形成过程中,以及作为建筑块.此外,该化合物还因其生物活动进行了研究,包括潜在的诱变效应,需要认真处理和考虑安全协议.该化合物在有机溶剂中溶解,其再活性受氨基组的存在影响,这些组可参与各种化学反应,包括cyll and alkylation.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号5405-53-8 2,7-硝基芴 | CAS号1221066-40-5 N2,N7-bis(diphe... | CAS号1214-32-0 7-硝基-9H-芴-2-胺 | CAS号604-94-4 2,7-dinitrophen... | CAS号304-28-9 2,7-二(乙酰氨基)芴 | CAS号434293-70-6 N,N'-fluorene-2... | CAS号86-73-7 芴 | CAS号607-57-8 2-硝基芴 | CAS号17557-76-5 4,4‘-二氨基联苯-2,2'-二羧酸 | CAS号861525-32-8 bis-(5-amino-2-... | CAS号2195-50-8 9H-Fluorene,2,7... | CAS号86-73-7 芴 | CAS号2915-84-6 2,7-二氨基-9H-芴-9-酮 | CAS号16218-28-3 2,7-二碘芴 | CAS号304-28-9 2,7-二(乙酰氨基)芴 | CAS号2048-03-5 9H-Fluorene-2,7... | CAS号7072-11-9 9H-Fluorene-2,7... | CAS号391-57-1 2,2,2-trifluoro...

合成工艺路线路线简述

  • 合成目标产物 2,7-Diaminofluorene 主要起始原料 2,7-Dinitrofluorene
  • (文献来源)合成步骤主要原料 2,7-Dinitrofluorene
📜2,7-二硝基芴置于盐酸,碳酸氢钠,Tin(Ll) Chloride体系中,用 乙醚,水 作为反应溶剂,化学反应 4.0H,反应生成 2,7-二氨基芴
参考文献:Tetraguanidino-Functionalized Phenazine And Fluorene Dyes: Synthesis,Optical Properties And Metal Coordination
标题:Tetraguanidino-Functionalized Phenazine And Fluorene Dyes: Synthesis,Optical Properties And Metal Coordination
摘要:苯并嗪与胍基团的官能化导致了新的高荧光染料和配体,并且金属配位明显改变了光学性质.
DOI:10.1039/c4Dt03572K

海关参考信息

专利信息


专利号:US-8034895-B2
优先权日:2004-02-04
标题 :Conjugated thiophenes having conducting properties and synthesis of same
发明人:SKENE WILLIAM G
权利人:UNIV MONTREAL
摘要:The present invention relates to conjugated oligomers and polymers comprising aromatic thiophene cores. The conjugated materials are obtained by simple and efficient condensation of an aryl diamine and an aryl dialdehyde or a bifunctional aryl moiety comprising both an aldehyde and an amine. Condensation of the complementary moieties at temperatures ranging from ambient to refluxing temperatures in various solvents resulted in conjugated oligomers and polymers that can subsequently be cast into thin films. Oligomerization and polymerization can be done under mild conditions with removal of the resulting water bi-product responsible for shifting the equilibrium in favor of the conjugated products. The resulting conjugated compounds can be made conducting with dopants affording electrically conducting materials of either p-type or n-type conductors depending on the dopant selected.

专利号:US-2009111737-A1
优先权日:1999-05-24
标题:Novel antibacterial agents
发明人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.

专利号:US-2013102730-A1
优先权日:2010-04-02
标 题:Polyamine-containing polymers and methods of synthesis and use
发明人:JOST ROBERT W; ULUDAG HASAN; BOLUK MEHMET YAMAN
权利人:JOST ROBERT W; ULUDAG HASAN; BOLUK MEHMET YAMAN; ALBERTA INNOVATES TECHNOLOGY FUTURES
摘要:The present invention relates to polyamine-containing polymers and methods of their synthesis and use. The polymer may be hydroxyethylcellulose, dextran, poly(vinyl alcohol) or poly(methyl acrylate).

专利号:US-2007287842-A1
优先权日:2004-02-04
标题 :Conjugated Thiophenes Having Conducting Properties and Synthesis of Same

专利号:US-2012004386-A1
优先权日:2004-02-04
标题 :Conjugated thiophenes having conducting properties and synthesis of same

专利号:US-7973158-B2
优先权日:2006-11-29
标 题 :Method of preparing benzoxazines
发明人:TADEN ANDREAS J; LIU PUWEI; WONG ALEX C; PARKER ERIC A
权利人:HENKEL CORP; HENKEL AG & CO KGAA
摘要:This invention relates to a novel synthesis for the preparation of benzoxazine components from phenolic components, aldehyde components, and amine components in a solvent other than toluene.

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品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

[参考文献]: B A Callus, Et Al. Diaminofluorene Is More Sensitive Than Benzidine For Detecting Hemoglobin In Erythropoietin Responsive J2E Cells. Hemoglobin. 1995 Jan-Mar;19(1-2):7-19.
[参考文献]: C A Maack, Et Al. Procarcinogen Activation By Rat And Human Mammary Extracts. Carcinogenesis. 1986 Jun;7(6):899-905.
[参考文献]: K Fujikawa, Et Al. Genotoxic Potency In Drosophila Melanogaster Of Selected Aromatic Amines And Polycyclic Aromatic Hydrocarbons As Assayed In The Dna Repair Test. Mutat Res. 1993 Dec;290(2):175-82.
[参考文献]: N L Kobrinsky, Et Al. Endothelial Cells Suppress Granulocyte Clusters And Stimulate Large Granulocyte Colonies In Culture. Clin Invest Med. 1985;8(2):160-6.
[参考文献]: R E Worthington, Et Al. Quantitation Of Erythroid Differentiation In Vitro Using A Sensitive Colorimetric Assay For Hemoglobin. Exp Hematol. 1987 Jan;15(1):85-92.

合成参考文献


参考文献:10.1007/s10895-006-0074-z
摘要:Enoch IV, Swaminathan M. Fluorimetric study on molecular recognition of beta-cyclodextrin with 2-amino-9-fluorenone. J Fluoresc. 2006 Jul;16(4):501–10. doi: 10.1007/s10895-006-0074-z.
摘要:Merck Index - O'Neil MJ, Heckelman PE, Dobbelaar PH, Roman KJ (eds). The Merck Index, An Encyclopedia of Chemicals, Drugs, and Biologicals, 15th Ed. Cambridge, UK: The Royal Society of Chemistry, 2013.
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