CAS: 490-98-2; 2-(Dimethylamino)Ethyl 4-(Butylamino)-2-Hydroxybenzoate

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CAS号123-72-8 正丁醛 | CAS号619-19-2 4-硝基水杨酸 | CAS号101084-96-2 2-甲氧基-4-硝基苯甲腈 | CAS号78987-51-6 ethyl 2-hydroxy... | CAS号65-49-6 对氨基水杨酸 | CAS号107-99-3 2-氯-N,N-二甲基乙胺

📜4-硝基水杨酸置于吡啶,盐酸,Palladium On Activated Charcoal,氯化亚砜,乙醇,Sodium Carbonate,溶剂黄146,Sodium Iodide,锌,苯体系中,化学反应生成 羟丁卡因
参考文献:Derivatives Of 4-Amino-2-Hydroxybenzoic Acid. I
标题:Derivatives Of 4-Amino-2-Hydroxybenzoic Acid. I
摘要:
DOI:10.1021/ja01152A032

专利信息

专利号:US-7993390-B2
优先权日:2002-02-08
标 题:Implantable or insertable medical device resistant to microbial growth and biofilm formation
发明人：MILLER KATHLEEN M; BUCAY-COUTO WEENNA; LI JIANMIN
权利人:BOSTON SCIENT SCIMED INC
摘要:Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and/or a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents.