CAS: 2267-25-6; 2-Chloro-4-Fluoroanisole

上下游产品

CAS号459-60-9 4-氟苯甲醚 | CAS号110-71-4 乙二醇二甲醚 | CAS号1978-39-8 5-氟-2-甲氧基苯胺 | CAS号445-83-0 4-氟-2-硝基苯甲醚 | CAS号1996-41-4 2-氯-4-氟苯酚 | CAS号1017777-58-0 2-氯-6-氟-3-甲氧基苯胺 | CAS号146447-18-9 5-溴-2-氯-4-氟苯甲醚 | CAS号1996-41-4 2-氯-4-氟苯酚 | CAS号886499-40-7 2-氯-6-氟-3-甲氧基苯甲酸 | CAS号960591-76-8 2-(5-fluoro-2-m...

2-氯苯甲醚置于potassium Fluoride,18-冠醚-6,Copper(II) Bis(Trifluoromethanesulfonate)体系中,用 二氯甲烷,N,N-二甲基甲酰胺,乙腈 用作溶剂,化学反应 6.0H,反应生成2-氯-4-氟苯甲醚
参考文献:含有邻侧臂的不对称二芳基碘鎓盐的氟化;侧臂对选择性的影响.
标题:含有邻侧臂的不对称二芳基碘鎓盐的氟化;侧臂对选择性的影响.
摘要:在三氟甲磺酸存在下,活化的芳烃与两种不同的氟代烷试剂1和2反应,仅制备对位取代的二芳基碘鎓盐.对于氟碘烷1,不对称二芳基碘鎓盐含有邻-丙-2-醇侧臂,而醇侧臂被消除以在与氟碘烷 2 的反应中形成邻-苯乙烯侧臂.只有含有苯乙烯侧臂的二芳基碘鎓盐被成功地氟化,从而以非常好的收率提供对氟化芳烃.
Doi:10.1039/d0Ob01401J

专利信息

专利号:US-5600016-A
优先权日:1990-10-18
标 题 :Benzoyl derivatives and synthesis thereof
发明人：HAMPER BRUCE C; LESCHINSKY KINDRICK L
权利人:MONSANTO CO
摘要:The present invention relates to novel 4-halo-2-fluoro-5-alkoxybenzoyl compounds and their methods of manufacture. These compounds are useful for the preparation of agricultural chemicals and medicines, particularly as intermediates for an active class of arylhaloalkylpyrazole and aryl alkylsulfonylpyrazole herbicides.

专利号:EP-0772579-B1
优先权日:1994-07-20
标 题:Benzoyl derivatives and synthesis thereof
发明人：HAMPER BRUCE CAMERON; LESCHINSKY KINDRICK LEE
权利人:MONSANTO CO
摘要:The present invention relates to novel 4-halo-2-fluoro-5-alkoxybenzoyl compounds and their methods of manufacture. These compounds are useful for the preparation of agricultural chemicals and medicines, particularly as intermediates for an active class of arylhaloalkylpyrazole and aryl alkylsulfonylpyrazole herbicides.

专利号:US-7196090-B2
优先权日:2002-07-25
标题 :Kinase inhibitors
发明人：CONNOLLY CLEO J CHIVIKAS; DEUR CHRISTOPHER JAMES; HAMBY JAMES MARINO; HOYER DENTON WADE; LIMBERAKIS CHRIS; REED JESSICA ELIZABETH; SCHROEDER MEL CONRAD; TAYLOR CLARKE
权利人:WARNER LAMBERT CO
摘要:This invention provides phenyl-substituted pyrimidopyrimidines, dihydropyrimido-pyrimidines, pyridopyrimidines, naphthyridines, and pyridopyrazines of the general formula: n nthat inhibit cyclin-dependent kinase and tyrosine kinase enzymes, methods and intermediate compounds for their synthesis, as well as pharmaceutical compositions and methods for their use in treating, inhibiting or preventing maladies associated with cell proliferative disorders, including angiogenesis, atherosclerosis, restenosis, and cancer.

专利号:US-9067934-B2
优先权日:2011-03-31
标题 :Bicyclic pyridinones
发明人：PETTERSSON MARTIN YOUNGJIN; JOHNSON DOUGLAS SCOTT; SUBRAMANYAM CHAKRAPANI; O'DONNELL CHRISTOPHER JOHN; AM ENDE CHRISTOPHER WILLIAM; FISH BENJAMIN ADAM; GREEN MICHAEL ERIC; MULLINS PATRICK BRADLEY; STIFF CORY MICHAEL; TRAN TUAN PHONG; NAVARATNAM THAYALAN
权利人:PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I n nas defined herein. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.