CAS: 172152-36-2; 2-(((4-Methoxy-3-Methylpyridin-2-yl)Methyl)Sulfinyl)-6-(1H-Pyrrol-1-yl)-1H-Benzo[d]Imidazole

上下游产品

2-[[(4-甲氧基-3-甲基-2-吡啶基)甲基]硫基]-6-(1H-吡咯-1-基)-1H-苯并咪唑 Ilaprazole Sulfide 172152-35-1

5-(1H-吡咯烷-1-基)-2-巯基苯并咪唑置于间氯过氧苯甲酸,Sodium Hydroxide体系中,用 甲醇,氯仿 用作溶剂,化学反应 1.5H,反应生成艾普拉唑
参考文献:一种含艾普拉唑钠的药物组合物及其制备方 法
标题:一种含艾普拉唑钠的药物组合物及其制备方 法
摘要:本发明涉及一种含艾普拉唑钠的药物组合物及其制备方法,所述药物组合物由艾普拉唑钠和艾普拉唑的衍生物组成,其中,所述艾普拉唑衍生物为艾普拉唑砜,艾普拉唑硫醚,艾普拉唑羧基鎓内盐,艾普拉唑羟基鎓内盐,艾普拉唑巯甲基鎓内盐,艾普拉唑甲基鎓内盐,艾普拉唑硫氰甲基鎓内盐,艾普拉唑二硫二聚体,艾普拉唑三硫二聚体和艾普拉唑氮氧化物.所述药物组合物可用于治疗消化性溃疡出血和应激性溃疡以及预防重症疾病引起的上消化道出血.

专利信息

专利号:US-2008280855-A1
优先权日:2005-06-22
标 题 :Process For the Production of Intermediates For the Preparation of Tricyclic Benzimidazoles
发明人：CHIESA MARIA VITTORIA; PALMER ANDREAS; BUHR WILM; ZIMMERMANN PETER JAN; BREHM CHRISTOF; SIMON WOLFGANG-ALEXANDER; POSTIUS STEFAN; KROMER WOLFGANG; ZANOTTI-GEROSA ANTONIO
权利人:NYCOMED GMBH
摘要:The invention relates to a process for the synthesis of compounds of the formula 1-a and compounds of the formula 1-b. n n n n n n n n n n The compounds of the formula 1-a and the compounds of the formula 1-b, in which the substituents R1, R2, R3, and Ar have the meanings indicated in the description, are valuable intermediates for the preparation of pharmaceutically active compounds.

专利号:US-9631181-B2
优先权日:2009-12-08
标 题 :Synthesis of prazole compounds
发明人：BONG YONG KOY; CLAY MICHAEL D; COLLIER STEVEN J; MIJTS BENJAMIN; VOGEL MICHAEL; ZHANG XIYUN; ZHU JUN; NAZOR JOVANA; SMITH DEREK J; SONG SHIWEI
权利人:CODEXIS INC
摘要:The present disclosure relates to non-naturally occurring monooxygenase polypeptides useful for preparing prazole compounds, polynucleotides encoding the polypeptides, and methods of using the polypeptides.

专利号:JP-2011520873-A
优先权日:2008-06-12
标题 :Method for preparing intermediate compounds for the synthesis of anti-ulcer drugs

专利号:US-8895271-B2
优先权日:2009-12-08
标题:Synthesis of prazole compounds

专利号:EP-2510089-B1
优先权日:2009-12-08
标 题 :Synthesis of prazole compounds

专利号:CN-109053561-A
优先权日:2018-07-19
标 题 :Synthesis method of hydroxymethylpyridine nitroxide derivatives in proton pump inhibitor medicine