CAS: 144284-24-2; 2,3,4-Trifluorobenzyl Alcohol
该化合物是一种含分子式C7H5F3O的氟芳醇,其特点是苯环上存在三个氟原子,这增强了其电子提取特性,并影响其在合成应用中的回活动.它作为有机合成的多种中间体,特别是在制备药品,农用化学品和特殊材料方面.三氟甲基和氢氧基功能组为进一步衍生提供了选择性的再活动,如乙化或酯化.它的稳定性和明确界定的结构使它成为研究人员寻求将氟元素纳入目标分子的一个有价值的建筑块.
相似化合物
61079-72-9 161793-17-5 351354-50-2物理性质
MSDS等安全信息
欧盟法规
ECHA物质C&L通报上下游产品
2,3,4,-trifluorobenzoic acid tertbutyldiphenyl(2,3,4-trifluorobenzyloxy)silane合成工艺路线路线简述
- 合成目标产物 2,3,4-Trifluorobenzyl Alcohol 主要起始原料 2,3,4-Trifluorobenzoic Acid
- (文献来源)合成步骤主要原料 2,3,4-Trifluorobenzoic Acid
📜2,3,4-三氟苯甲酸置于锂硼氢体系中,用 四氢呋喃 用作溶剂,以92%的收率获得2,3,4-三氟苯甲醇
参考文献:Beyond The Mek-Pocket: Can Current Mek Kinase Inhibitors Be Utilized To Synthesize Novel Type Iii Nckis Does The Mek-Pocket Exist In Kinases Other Than Mek
标题:Beyond The Mek-Pocket: Can Current Mek Kinase Inhibitors Be Utilized To Synthesize Novel Type Iii Nckis Does The Mek-Pocket Exist In Kinases Other Than Mek
摘要:An Approach And Preliminary Results For Utilizing Legacy Mek Inhibitors As Templates For A Reiterative Structural Based Design And Synthesis Of Novel,Type Iii Nckis (Non-Classical Kinase Inhibitors) Is Described. Evidence Is Provided That The Mek-Pocket Or Pockets Closely Related To It May Exist In Kinases Other Than Mek. (C) 2008 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Bmcl.2008.10.108
海关参考信息
- 2902300000-甲苯
2905110000-甲醇
2906210000-苄醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2008176865-A1
优先权日:2005-06-15
标 题:Substituted arylpyrazoles
发明人：BILLEN DENIS; BOYLE JESSICA; CRITCHER DOUGLAS JAMES; GETHIN DAVID MORRIS; HALL KIM THOMAS; KYNE GRAHAM MICHAEL
权利人:PFIZER LTD
摘要:This invention relates to a range of 1-aryl-4-cyclopropylpyrazoles in which the cyclopropyl ring is substituted at the angular position, and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes to their synthesis and their use as parasiticides.
专利号:US-7825149-B2
优先权日:2006-01-19
标 题 :Substituted imidazoles
发明人：CHUBB NATHAN ANTHONY LOGAN; COX MARK ROGER; DAUVERGNE JEROME SEBASTIEN; EWIN RICHARD ANDREW; LAURET CHRISTELLE
权利人:PFIZER LTD
摘要:This invention relates to a range of alpha substituted 2-benzyl substituted imidazole compounds and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes for their synthesis and their use as parasiticides.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考DOI号:10.1016/j.bmcl.2008.10.108
📝 需求与反馈
尽可能描述清楚需求与问题信息
