CAS: 124882-74-2; N-[(2E)-3-(2-Furanyl)-1-Oxo-2-Propen-1-Yl]Glycine
该化合物是有机化合物,其独特的结构特征包括一个富林基体组和一个乙酰甘油化合物,该化合物通常具有与呋喃衍生物和氨基酸有关的特性,例如极地溶剂中的中溶性,以及由于功能组的存在而具有的潜在反应性.氟化烃部分有助于其芳香特性,而乙酰糖成分可能会影响其生物活动和相互作用.该化合物可能在不同领域引起兴趣,包括医药化学和材料科学,因为它在药物开发或作为有机合成的建筑块中的潜在应用.其稳定性,再活性和与生物目标的具体互动将取决于周围的条件,例如pH值和温度.总体而言,跨N(2-硫基)甘油甘油是连接有机化学和生物化学领域的化合物的一个令人感兴趣的例子.
- 英文名称N-[(2E)-3-(2-Furanyl)-1-Oxo-2-Propen-1-Yl]Glycine
- 中文名称N-[(2E)-3-(2-呋喃基)-1-氧代-2-丙烯-1-基]甘氨酸
- IUPAC名称(E)-(3-(furan-2-yl)acryloyl)glycine
- 其它别名2-[[(E)-3-(Furan-2-yl)Prop-2-Enoyl]Amino]Acetic Acid; 2-[(2E)-3-(Furan-2-yl)Prop-2-Enamido]Acetic Acid; N-[3(2-Furylacryloyl)]-Glycine; N-Alpha-(3-(2-Furyl)-Acryloyl)-Glycine; Trans-N-(2-Furfurylideneacetyl)Glycine; Fa-Glycine; Fa-Gly-Oh; 3-(2-Furyl)Acryloyl-Glycine
- CAS编号124882-74-2
- MFCD编号:MFCD00080918
- 分子式:C9H9NO4分子量:195.17
- 产品CID: 364878
- 产品分类有机原料→分子砌块→芳杂环类化合物→呋喃类化合物
相似化合物
29243-71-8 103972-52-7 90281-70-2物理性质
上下游产品
CAS号459-73-4 2-胺基乙酸乙酯 | CAS号539-47-9 2-呋喃丙烯酸 | CAS号519054-08-1 (E)-1-(1H-1,2,3... | CAS号56-40-6 甘氨酸 | CAS号26400-33-9 N-(3-[2-呋喃]丙烯)甘氨酸亮酰胺 | CAS号26400-34-0 FA-Gly-Phe-NH2 | CAS号56-40-6 甘氨酸合成工艺路线路线简述
📜3-(Fur-2-yl)Crotonic Acid置于n,N-二异丙基乙胺,N-[(Dimethylamino)-3-Oxo-1H-1,2,3-Triazolo[4,5-B]Pyridin-1-Yl-Methylene]-N-Methylmethanaminium Hexafluorophosphate,Sodium Hydroxide体系中,用 1,4-二氧六环,二氯甲烷 用作溶剂,化学反应 21.0H,反应生成反-N-(2-亚糠基乙酰)甘氨酸
参考文献:下一代荧光蛋白酶测定:7-硝基苯甲-2-氧杂-1,3-二唑-4-基-酰胺 (Nbd-酰胺) 作为跨类蛋白酶底物
标题:下一代荧光蛋白酶测定:7-硝基苯甲-2-氧杂-1,3-二唑-4-基-酰胺 (Nbd-酰胺) 作为跨类蛋白酶底物
摘要:通过使用硝基苯并呋喃 (Nbd) 荧光团,开发了新一代颠覆性的新型蛋白酶检测底物.通过跨不同蛋白酶类别的应用,这一突破有望决定性地改进蛋白酶药物发现中的荧光测定.
Doi:10.1002/chem.202301855
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2912110000-甲醛
2912120000-乙醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-6562844-B2
优先权日:1998-01-23
标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.
专利号:US-7002020-B1
优先权日:1998-01-23
标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.
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品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1007/s00253-015-6923-4
摘要:Maeda H, Nakagawa K, Murayama K, Goto M, Watanabe K, Takeuchi M, Yamagata Y. Cloning a neutral protease of Clostridium histolyticum, determining its substrate specificity, and designing a specific substrate. Applied Microbiology and Biotechnology. 2015 Aug 26;99(24):10489–99. doi: 10.1007/s00253-015-6923-4.
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