CAS: 124-48-1; Chlorodibromomethane

该化合物是一种卤化有机化合物,属于卤化烷组,是一种无色液体,有甜味,经常用作溶剂和合成其他化学化合物,二溴氯甲烷的分子式为CBr2ClH,表明存在两个溴原子,一个氯原子和一个与碳原子相连的氢原子.该化合物比水密度高,沸点相对较低,导致其挥发性.二溴氯甲烷被归类为潜在的环境污染物,特别是因其在臭氧消耗中的作用及其在某些工业应用中的存在,还因其潜在的健康危害而得到承认,包括对肝脏和肾脏的接触影响.适当处理和处置对于减轻其环境影响和健康危害至关重要.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

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CAS号127-09-3 乙酸钠 | CAS号67-66-3 氯仿 | CAS号75-25-2 三溴甲烷 | CAS号74-87-3 氯甲烷 | CAS号34557-54-5 methane | CAS号142-28-9 1,3-二氯丙烷 | CAS号627-30-5 3-氯-1-丙醇 | CAS号41036-93-5 α-bromo-α-chlor... | CAS号75-27-4 一溴二氯甲烷标准溶液 | CAS号125013-86-7 (1R,4S,4aR,8aS)... | CAS号125013-87-8 (1R,4S,4aR,8aS)... | CAS号542-92-7 环戊二烯 | CAS号108-90-7 氯苯 | CAS号119-64-2 1,2,3,4-四氢萘(THN) | CAS号83692-65-3 (11R,6S)- and (... | CAS号83692-67-5 anti-11-chlorob... | CAS号826-73-3 1-苯并环庚酮 | CAS号83692-66-4 anti-6-chlorome... | CAS号83692-63-1 cis-tricyclo[5....

合成工艺路线路线简述

    📜氯甲烷置于pumice Stone,溴体系中,化学反应生成氯二溴甲烷
    参考文献:Besson,Chemische Berichte,25 Ref. <1892>,15
    标题:Besson,Chemische Berichte,25 Ref. <1892>,15

    海关参考信息

    专利信息


    专利号:US-7767826-B2
    优先权日:2007-10-05
    标题 :Process for the synthesis of L-(+)-ergothioneine
    发明人:TRAMPOTA MIROSLAV
    权利人:PHARMATECH INTERNATIONAL INC
    摘要:This invention relates to a novel process for the preparation of optically pure L-(+)-ergothioneine. The process for the chemical synthesis of L-ergothioneine comprises steps which consist of reacting L-histidine alkyl ester with an acid halide, chloroformate or pyrocarbonate in the presence of a base, hydrolysis of the alkyl-(S,Z)-2,4,5-triamidopent-4-enoate to obtain a (S)-alkyl 2,5-diamido-4-oxopentanoate, acid catalyzed hydrolysis of the (S)-alkyl 2,5-diamido-4-oxopentanoate followed by reaction with a metal thiocyanate to obtain the thiohistidine, protection of the sulfur of thiohistidine as the tert-butyl thioether, dialkylation of the primary amine to obtain a tertiary amine, quaternization of the tertiary amine, and removal of the protecting group to obtain the desired (S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trialkylammonio)propanoate (I). This process affords a better yield and is capable of practical application at large scale.

    专利号:US-6175009-B1
    优先权日:1999-11-18
    标题:Process for the preparation of quinazolinones
    发明人:CONFALONE PASQUALE NICHOLAS; MAGNUS NICHOLAS ANDREW; STORACE LOUIS
    权利人:DU PONT PHARM CO
    摘要:The present invention relates generally to an asymmetric synthesis of 4,4-disubstituted-3,4-dihydro-2(1H)-quinazolinones, and intermediates thereof. The target compounds are useful for the treatment of human immunodeficiency virus (HIV) as an inhibitor of reverse transcriptase.

    专利号:US-6022977-A
    优先权日:1997-03-26
    标 题 :Dynamic resolution of isoxazoline thioesters to isoxazoline carboxylic acids
    发明人:ZHANG LIN-HUA; ANZALONE LUIGI; PESTI JAAN A; YIN JIANGUO
    权利人:DU PONT PHARM CO
    摘要:The present invention relates generally to a novel method for preparation of substituted isoxazolin-5-yl acetic acid in high optical purity from a stereoisomeric mixture of an esterified substituted isoxazolin-5-yl acetate. The products are useful in the synthesis of compounds for pharmaceuticals, especially the treatment of thrombolytic disorders, and agricultural products.

    专利号:US-8129560-B2
    优先权日:2005-08-15
    标 题 :Process for the synthesis of mandipropamid and derivatives thereof
    发明人:BOWDEN MARTIN CHARLES; CLARK THOMAS AITCHESON; GIORDANO FANNY; JAU BEAT; SCHNEIDER HANS-DIETER; SEIFERT GOTTFRIED; ZELLER MARTIN; FABER DOMINIK; WISS JUERG
    权利人:BOWDEN MARTIN CHARLES; CLARK THOMAS AITCHESON; GIORDANO FANNY; JAU BEAT; SCHNEIDER HANS-DIETER; SEIFERT GOTTFRIED; ZELLER MARTIN; FABER DOMINIK; WISS JUERG; SYNGENTA CROP PROT INC
    摘要:A process for the preparation of a compound of formula (I), the process comprising: (i) the reaction of a compound of formula (III), with a compound of formula (IV) to give a compound of formula (II), and (ii) the reaction of the compound of formula (II) with a leaving group, to give the compound of formula (I).

    专利号:WO-0029391-A1
    优先权日:1998-11-19
    标题 :Process for the preparation of quinazolinones
    发明人:CONFALONE PASQUALE NICHOLAS; MAGNUS NICHOLAS ANDREW; STORACE LOUIS
    权利人:DU PONT PHARM CO
    摘要:The present invention relates generally to an asymmetric synthesis of 4,4-disubstituted-3,4-dihydro-2(1H)-quinazolinones, and intermediates thereof. The target compounds are useful for the treatment of human immunodeficiency virus (HIV) as an inhibitor of reverse transcriptase.

    专利号:US-8563760-B2
    优先权日:2009-08-31
    标 题:Process for the synthesis of long-chain fatty acids
    发明人:FAUQ ABDUL H; EDWARDS ALBERT O
    权利人:FAUQ ABDUL H; EDWARDS ALBERT O; MAYO FOUNDATION
    摘要:This invention relates to processes for preparing long-chain fatty acids of Formula I: n nand salts thereof, as well as intermediates for the processes, wherein L 1 and L 2 are described herein.

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Toxicology and Applied Pharmacology., 44(213), 1978 []
    摘要:NIOSH. NIOSH Pocket Guide to Chemical Hazards. DHHS (NIOSH) Publication No. 97-140. Washington, D.C. U.S. Government Printing Office, 1997., p. 65
    摘要:USEPA/Office of Water; Federal-State Toxicology and Risk Analysis Committee (FSTRAC). Summary of State and Federal Drinking Water Standards and Guidelines (11/93) To Present
    摘要:Kuney, J.H. (ed.). CHEMCYCLOPEDIA 90. Washington, DC: American Chemical Society, 1990., p. 288
    摘要:Warner HP et al, Determination of Henry's Law Constants of Selected Priority Pollutants. USEPA/600/D-87/229, NTIS PB87-212684 (1987)
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