CAS: 94483-64-4; N-((2R,3R,4R,5S,6R)-4,5-Dihydroxy-6-(Hydroxymethyl)-2-(Pentyloxy)Tetrahydro-2H-Pyran-3-yl)Acetamide

该化合物是一种以其结构为特征的胶质衍生物,其结构包括一个与五氟基组和乙基氨基功能组相连的胶晶体糖单位,该化合物一般是白色至非白色固体,可溶解于水和甲醇等极溶剂,因为甘基甘醇溶液中存在氢氧基组,乙酰氨基组可提高其溶性和再活性,使其在各种生物化学应用中有用.它可能显示生物活动,有可能在酶反应中起到基质或抑制剂的作用.青丁基组的存在可影响其亲脂性,影响其与生物膜的相互作用.与许多玻璃表面一样,它可能参与玻璃化反应,这对于更复杂的碳水化合物合成或药物开发的药用化学至关重要.应当与任何化学物质一样,观测安全数据和处理预防措施,以确保适当的实验室做法.

英文名称N-((2R,3R,4R,5S,6R)-4,5-Dihydroxy-6-(Hydroxymethyl)-2-(Pentyloxy)Tetrahydro-2H-Pyran-3-yl)Acetamide
中文名称戊烷基-2-乙酰氨基-2-脱氧-β-D-葡萄糖苷
IUPAC名称N-((2R,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(pentyloxy)tetrahydro-2H-pyran-3-yl)acetamide
其它别名Amyl2-Acetamido-2-Deoxy-B-D-Glucopyranoside; Amyl 2-Acetamido-2-Deoxy-Ss-D-Glucopyranoside; Amyl-2-Acetamido-2-Deoxy-β-D-Glucopyranoside; Amyl 2-Acetamido-2-Deoxy-Beta-D-Glucopyranoside; N-[4,5-Dihydroxy-6-(Hydroxymethyl)-2-Pentoxy-3-Oxanyl]Acetamide; Pentyl 2-(Acetylamino)-2-Deoxy-Beta-D-Glucopyranoside; B-D-Glucopyranoside, Pentyl2-(Acetylamino)-2-Deoxy-; Pentyl 2-Acetamido-2-Deoxy-β-D-Glucopyranoside
CAS编号94483-64-4
MFCD编号:MFCD08704001
分子式:C13H25NO6分子量:291.34
产品CID: 1995672
产品分类生物化工 → 糖类化合物 → 单糖

相似结构搜索
InChIKey: TXAKGSVWAUXDOK-UHFFFAOYSA-N
InChI=1S/C13H25NO6/c1-3-4-5-6-19-13-10(14-8(2)16)12(18)11(17)9(7-15)20-13/h9-13,15,17-18H,3-7H2,1-2H3,(H,14,16)/t9-,10-,11-,12-,13-/m1/s1
计算化学: 氢键受体数6.0氢键供体数4.0可旋转键数7.0

MSDS等安全信息

警示词Warning
危险描述H302-H315-H319-
防范说明P264-P270-P280-P301+P312+P330-P302+P352-P305+P351+P338-P332+P313-P337+P313-P501-

上下游产品

pentyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside 1,3,4,6-tetra-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranose pentan-1-ol Pentyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranoside

合成工艺路线路线简述

合成目标产物 Amyl 2-Acetamido-2-Deoxy-Beta-D-Glucopyranoside 主要起始原料 Amyl 2-Acetamido-3,4,6-Tri-O-Acetyl-2-Deoxy-Beta-D-Glucopyranoside
(文献来源)合成步骤主要原料 Amyl 2-Acetamido-3,4,6-Tri-O-Acetyl-2-Deoxy-Beta-D-Glucopyranoside

📜2-脱氧-2-苯二酰亚胺-1,3,4,6-四-氧-乙酰-β-D-吡喃葡萄糖置于四氯化锡吡啶,Sodium Methylate,正丁胺体系中,用甲醇,乙醇,二氯甲烷作为反应溶剂,化学反应 15.0H,反应生成戊烷基-2-乙酰氨基-2-脱氧-β-D-葡萄糖苷
参考文献:A Spacer-Modified Disaccharide As A Photoaffinity Reagent For The Acceptor-Binding Area Of Bovine (1-> 4)-β-D-Galactosyltransferase: Comparison Of Its Acceptor Properties With Those Of Other 2-Acetamido-2-Deoxy-β-D-Glucopyranosides
标题:A Spacer-Modified Disaccharide As A Photoaffinity Reagent For The Acceptor-Binding Area Of Bovine (1-> 4)-β-D-Galactosyltransferase: Comparison Of Its Acceptor Properties With Those Of Other 2-Acetamido-2-Deoxy-β-D-Glucopyranosides
摘要:The Spacer-Modified Disaccharide 1,10-Di-O-(2-Acetamido-2-Deoxy-Beta-D-Glucopyranosyl)-2-Azi-1,10-Decanediol (10) That Mimics The Biantennary. Core Heptasaccharide Of N-Glycoproteins Has Been Synthesised. Compound 10 Is An Excellent Acceptor In Galactosyltransferase-Catalysed Galactosylation By Udp-Galactose,Is Superior (7-8-Fold) To Analogues That Have Only One Glcnac Unit,And Is An Efficient Photoaffinity Reagent For Galactosyltransferase. In The Presence Of Udp-Gal. No Photoaffinity Labelling By 10 Takes Place,Which Agrees The Mechanism Of Galactosyltransferase Action.
DOI:10.1016/s0008-6215(00)90925-X