CAS: 92761-26-7; ((1,4-Phenylenebis(Methaneylylidene))Bis(7,7-Dimethyl-2-Oxobicyclo[2.2.1]Heptan-1-Yl-3-Ylidene))Dimethanesulfonic Acid

该化合物是一种化学化合物,主要用作防晒剂,因为它能够吸收紫外线辐射,对UVA射线特别有效,因为据知紫外线有助于皮肤衰老和皮肤癌的发展.Ecamsule的特征是其光学性,这意味着在接触阳光时保持其有效性,使它在太阳保护配方中成为有价值的成分.该化合物经常与其他紫外线过滤器结合,以提供广谱保护.在溶解性方面,Ecamsule通常在有机溶剂中溶解,但水溶解性有限,影响化妆品的配方.已经对它的安全性进行了评估,并一般认为在热门应用中使用是安全的.在包括润滑剂,奶油和喷雾在内的各种日光产品中常见的Ecamsule,并因其对皮肤的轻度和最小的刺激潜力而得到青睐.

结构式图片

欧盟法规

统一分类与标签REACH注册ECHA物质欧盟化妆品法规附录六-准用紫外线吸收剂清单工作场所安全标识要求ECHA物质C&L通报REACH预注册废弃物危险特性清单

上下游产品

camphor-10-sulfonic acid terephthalaldehyde,

合成工艺路线路线简述

  • 90458-75-6 = 92761-26-7
    反应条件:1.1 Reagents: Hydrochloric Acid Solvents: Ethanol,Water; Ph 1 - 2,Rt -> 50 °C; 30 H,50 °C; 30 Min,50 °C
    标题:Preparation Method Of Sunscreen Agent Intermediate P-Xylylene Dicamphor Sulfonic Acid
    参考文献:World Intellectual Property Organization]

    5872-08-2 + 623-27-8 = 92761-26-7
    反应条件:1.1 Reagents: Sodium Methoxide,Hydrochloric Acid Solvents: Methanol,Toluene,Water; Reflux1.2 Neutralized
    标题:Method For Purifying Terephthalylidene Dicamphor Sulfonic Acid
    参考文献:World Intellectual Property Organization]

    5872-08-2 + 623-27-8 = 92761-26-7
    反应条件:1.1 Reagents: Sodium Methoxide Solvents: Methanol,Cyclohexane; 60 Min,75 °C1.2 Reagents: Sodium Methoxide Solvents: Methanol,Cyclohexane; 80 Min,70 °C1.3 Solvents: Water; Ph 2,70 °C -> 90 °C
    标题:Method For Preparing Terephthalylidene Dicamphorsulfonic Acid Sunscreen
    参考文献:China]

    = 92761-26-7 [标题:Reaction Conditions
    标题:Method For Acidification Of Terephthalylidene Dicamphorsulfonate Using Cation Exchange Fibers
    参考文献:Korea]

    = 92761-26-7 [标题:Reaction Conditions
    标题:3-Benzylidenecamphor Derivatives And Their Use In Protecting Against Uv Radiation
    参考文献:Federal Republic Of Germany]

    = 92761-26-7 [标题:Reaction Conditions
    标题:3-Benzylidenecamphorsulfonamide Derivatives,Cosmetics Containing Them And Their Use
    参考文献:Federal Republic Of Germany
Disodium Terephthalylidene Dicamphor Sulfonic Acid置于trilite Scr-Bh体系中,用 水 作为反应溶剂,以97%的收率获得产物依莰舒
参考文献:Wo2017/155217
标题:Wo2017/155217

海关参考信息

专利信息


专利号:US-2007243147-A1
优先权日:2004-07-24
标 题:Skin and/or Hair Composition Containing Compounds for Increasing The Tanning of Skin
发明人:WOLBER RAINER; TOM DIECK KAREN; SCHERNER CATHRIN; SCHLENZ KATHRIN; KRUSE INGE
权利人:BEIERSDORF AG
摘要:The invention relates to agents that are to be applied to the skin or hair and contain compounds for intensifying tanning of the skin and increasing melanin synthesis in skin or hair. The invention particularly relates to cosmetic or dermatological preparations. Using said preparations results in inducing and intensifying the tanning mechanisms of the skin, intensifying the hair color, and thus also increasing intrinsic protection of the skin or hair.

专利号:US-2007189984-A1
优先权日:2003-09-08
标题:Agents for use on skin and/or hair containing quadruply substituted cyclohexene compounds
发明人:WOLBER RAINER; SCHERNER CATHRIN; TOM DIECK KAREN; SCHLENZ KATHRIN; VIETZKE JENS-PETER
权利人:BEIERSDORF AF
摘要:The invention relates to agents for use on skin or hair, particularly for increasing skin tanning and the synthesis of melanin in skin or hair. The invention contains, in particular, cosmetic or dermatological preparations containing quadruply substituted cyclohexene compounds. The use of the preparations leads to the induction and intensification of the tanning mechanisms of skin, the intensification of hair color and thus also to an intensification of the skin's and hair's intrinsic protection.

专利号:EP-1493431-B1
优先权日:2003-07-03
标题:Use of an extract of bauhinia for the preparation of pharmaceutical and cosmetic compositions
发明人:WIRTH CORINNA DR; BUCHHOLZ HERWIG DR
权利人:MERCK PATENT GMBH
摘要:Use of an aqueous or aqueous-alcoholic extract (A) of Bauhinia is claimed to make a composition for cosmetic or pharmaceutical treatment of skin and hair. Use of an aqueous or aqueous-alcoholic extract (A) of Bauhinia is claimed to make a composition for: (a) care, preservation or improvement of the general condition of the skin or hair; (b) prevention and/or inhibition of the aging process for human skin or hair; (c) for promoting healing of wounds; (d) for prevention and/or treatment of skin diseases associated with abnormal keratinization, and (e) for prevention and/or treatment of all malignant or benign growths of the dermis or epidermis. An independent claim is also included for a composition containing (A). ACTIVITY : Dermatological; Vulnerary; Antiseborrheic; Antipsoriatic; Cytostatic; Antiinflammatory; Virucide. MECHANISM OF ACTION : Protein glycosylation inhibitor. In a test, human fibroblasts were cultured in the presence of Vitamin C to stimulate collagen synthesis, then lysed and labeled with tritiated glucose for 15 days, Proteins were removed, extraction and precipitation were carried and the amount of bound glucose measured by liquid scintillation counting. Addition of an aqueous-alcoholic extract of Bauhinia fortificata (0.03 mg/ml), reduced protein glycosylation to 55% of that in a control.

专利号:US-10722441-B2
优先权日:2016-01-15
标题:Noreugenin glycoside derivatives
发明人:CAROLA CHRISTOPHE; SCHULTE MICHAEL; RABAUSCH ULRICH; ROSENFELD HENNING; STREIT WOLFGANG
权利人:UNIV HAMBURG
摘要:A use of noreugenin glycoside derivatives of formulas I, II and III as a self-tanning substance or to increase the synthesis of melanin, improve melanin transport and/or improve the distribution of melanin in suprabasal layers, preparations containing noreugenin glycoside derivatives of formulas I, II and III, and noreugenin glycoside derivatives of formulas I, II and III.

专利号:US-2017304168-A1
优先权日:2012-05-11
标题 :Phenyl ketone derivatives as self-tanning agents
发明人:CAROLA CHRISTOPHE
权利人:MERCK PATENT GMBH
摘要:The present invention relates to the use of phenyl ketone derivatives of the formula I for use as self-tanning substance or for increasing melanin synthesis, improving melanin transport and/or improving the distribution of melanin in suprabasal layers, and to preparations comprising these phenyl ketone derivatives.

专利号:US-2020038306-A1
优先权日:2016-10-07
标题:Barbituric acid derivatives as self-tanning substances
发明人:OSTHOFF JULIAN; DRILLER HANSJUERGEN; CAROLA CHRISTOPHE; BACK ROBIN; KROHN MICHAEL
权利人:MERCK PATENT GMBH
摘要:The present invention relates to the use of barbituric acid derivatives of the formula I as self-tanning substance, for increasing melanin synthesis, for improving melanin transport and/or improving the distribution of melanin in superbasal layers, to preparations comprising these barbituric acid derivatives, and to specific barbituric acid derivatives.
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供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献


1: Matta MK, Zusterzeel R, Pilli NR, Patel V, Volpe DA, Florian J, Oh L, Bashaw E, Zineh I, Sanabria C, Kemp S, Godfrey A, Adah S, Coelho S, Wang J, Furlong LA, Ganley C, Michele T, Strauss DG. Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial. JAMA. 2019 Jun 4;321(21):2082-2091. doi: 10.1001/jama.2019.5586.
2: Hofer S, Stonig M, Wally V, Hartmann A, Fuchs D, Hermann M, Paparella M, Ganzera M, Gostner JM. Contradictory effects of chemical filters in UV/ROS- stressed human keratinocyte and fibroblast cells. ALTEX. 2019;36(2):231-244. doi: 10.14573/altex.1808201. Epub 2018 Nov 27. 152(5):511-2. doi: 10.1001/jamadermatol.2015.6069. 2(1):4. doi: 10.1007/s13555-012-0004-8. Epub 2012 Apr 17.
5: Kim D, Kim S, Kim SA, Choi M, Kwon KJ, Kim M, Kim DS, Kim SH, Choi BK. Simultaneous analysis and monitoring of 16 UV filters in cosmetics by high- performance liquid chromatography. J Cosmet Sci. 2012 Mar-Apr;63(2):103-17. 21(4):185-98. 83(2):95-103. 24(4):164-74. doi: 10.1111/j.1600-0781.2008.00365.x. 58(5 Suppl 2):S133-8. doi: 10.1016/j.jaad.2007.05.047. 391(3):859-66. doi: 10.1007/s00216-008-2013-0. Epub 2008 Mar 27. 21(2):89-97. doi: 10.1159/000112959. Epub 2008 Jan 11. 47(5):672. doi: 10.1331/JAPhA.2007.07527. Plastic Surgery Educational Foundation Technology Assessment Committee. Mexoryl: a review of an ultraviolet a filter. Plast Reconstr Surg. 2007 Sep 15;120(4):1071-5. doi: 10.1097/01.prs.0000280561.02915.3a. 49(1261):41-3. Erratum in: Med Lett Drugs Ther. 2007 Oct 8;49(1271):84. 11(6):8. 40(5):4. 20(5):243-7. doi: 10.1111/j.1600-0781.2004.00111.x. 16(6):343-55. doi: 10.1159/000072929. 977(2):277-80. doi: 10.1016/s0021-9673(02)01411-5. 16(6):250-5. doi: 10.1034/j.1600-0781.2000.160603.x.

合成参考文献


摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
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