CAS: 92511-12-1; Tert-Butyl(4-Iodobutoxy)Dimethylsilane

该化合物是一种有机硅化合物,其特征是硅功能组,含有硅结为有机组的硅;该化合物的特征是三丁基硅组,其体积大,其分支为碳基基,有可能影响其再活性和溶性;四丁基二丁基甲基硅的存在引入了卤素,可参与核循环替代反应,使该化合物在有机合成中有用;二甲基硅有助于分子的整体稳定性和再活动,因为硅原子可以形成各种联结和复合物;该化合物在室内温度下可能是无色的液体或固体,在有机溶剂中具有中度的挥发性和溶性;其独特的结构允许在材料科学,制药和化学合成等领域应用,特别是在涉及硅基中间体的反应中应用.应当参考安全数据,以便处理,因为碘的存在可能会对健康构成特定风险.

结构式图片

相似化合物

3210-08-0 78878-05-4 89043-32-3

欧盟法规

C&L通报

上下游产品

tetrahydrofuran tert-butyldimethylsilyl chloride 4-tert-butyldimethylsilyloxybutan-1-ol 4-iodo-butan-1-ol-1-(p-tolylsulfonyl)butane4-(tert-butyldimethylsilyl)oxy-1-(p-tolylsulfonyl)butane 4-(tert-butyldimethylsilyloxy)butyl phenyl sulfide 1,7-dioxaspiro[5.5]undecane (+)-(2S,4'R,6'R)-1-(10-tert-butyl-dimethylsilyloxy-1-trimethylsilyloxy-4,6-diphenyl-5-decylideneamino)-2-methoxymethyl-pyrrolidine

合成工艺路线路线简述

    📜4-(叔丁基二甲基甲硅烷基)氧代-1-丁醇置于4-二甲氨基吡啶,三乙胺,Sodium Iodide体系中,用 二氯甲烷,丙酮 作为反应溶剂,化学反应 14.0H,反应生成 叔丁基(4-碘丁氧基)二甲基硅烷
    参考文献:通过有机催化不对称分子内迈克尔加成反应合成阿替普嘌呤a环
    标题:通过有机催化不对称分子内迈克尔加成反应合成阿替普嘌呤a环
    摘要:阿托普嘌呤1的a环片段2A-B的不对称合成已通过15个步骤完成,其中硝基苯10的有机催化分子内迈克尔加成使ee高达70%.使用改进的mosher方法将2A和2B中两个连续碳中心的绝对构型分别指定为(4 S,5 R)和(4 R,5 R).
    DOI:10.1016/j.Tet.2013.02.078

    海关参考信息

    专利信息


    专利号:US-9839642-B2
    优先权日:2014-05-09
    标 题:Beta-tetrazolyl-propionic acids as metallo-beta-lactamase inhibitors
    发明人:TANG HAIFENG; YANG SHU-WEI; MANDAL MIHIR; SU JING; LI GUOQING; PAN WEIDONG; TANG HAIQUN; DEJESUS REYNALDA; PAN JIANPING; HAGMANN WILLIAM; DING FA-XIANG; XIAO LI; PASTERNAK ALEXANDER; HUANG YUHUA; DONG SHUZHI; YANG DEXI
    权利人:MERCK SHARP & DOHME
    摘要:The present invention relates to compounds of formula I that are metallo-β-lactamase inhibitors, the synthesis of such compounds, and the use of such compounds for use with β-lactam antibiotics for overcoming resistance.

    专利号:US-9896479-B2
    优先权日:2012-05-16
    标 题 :Functionalized naphthalene fluorophores
    发明人:BRUMMOND KAY M; KOCSIS LAURA S; BENEDETTI ERICA
    权利人:BRUMMOND KAY M; KAY M BRUMMOND
    摘要:Methods for the synthesis and use of functionalized, substituted naphthalenes are described. The functionalized, substituted naphthalenes display useful properties including liquid crystals and fluorescence properties, such as solvatochromatic fluorescence, with high quantum yields, Stoke's shift, and show emission maxima that are significantly red-shifted.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:The Asymmetric Synthesis Of Amines Via Nickel-Catalyzed Enantioconvergent Substitution Reactions
    作者:Ze-Peng Yang,Dylan J. Freas,Gregory C. Fu |发布日期:2021.2.24
    摘要:Dialkyl Carbinamines Do Not Provide General Access To Amines Wherein The Two Alkyl Groups Are Of Similar Size (E.G., Ch2R Versus Ch2R1). Herein, We Report Two Mild Methods For The Catalytic Enantioconvergent Synthesis Of Protected Dialkyl Carbinamines, Both Of Which Use A Chiral Nickel Catalyst To Couple An Alkylzinc Reagent (1.1-1.2 Equiv) With A Racemic Partner, Specifically, An α-Phthalimido Alkyl Chloride

    合成参考文献


    摘要:Li, Y.; Xie, W.; Jiang, X., Science of Synthesis Knowledge Updates, (2016) 2, 27.
    摘要:Bartels, F.; Zimmer, R.; Christmann, M., Science of Synthesis Knowledge Updates, (2017) 3, 282.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知