CAS: 815610-16-3; 2-Amino-4-Iodopyrimidine
该化合物是具有湿性环状结构的杂交有机化合物,含有氮和碘替代物,该化合物的特点是2位置的氨基质组(-NH2),2位置的碘原子和4位置的氰胺环的碘原子.这一配置有助于其在药用化学中的潜在反应和应用,特别是在药品开发中.碘原子的存在可以加强该化合物的生物活动并影响其与生物目标的相互作用.此外,氨基亚基农组可以参与氢的结合,使其成为有机合成中的多用途构件.该化合物一般在室温下固态,在极溶剂中可能表现出中等溶性.其特性,如熔点,沸点和光谱特性,可以根据样品的具体条件和纯度而变化.
相似化合物
1538583-11-7 2680726-13-8 861031-48-3物理性质
MSDS等安全信息
欧盟法规
C&L通报上下游产品
CAS号3993-78-0 2-氨基-4-氯嘧啶合成工艺路线路线简述
- 3993-78-0 = 815610-16-3
反应条件:1.1 Reagents: Hydrogen Iodide Solvents: Water; 0 °C; 3 H,Rt
标题:Synthesis And Structure-Activity Relationship Of Trisubstituted Thiazoles As Cdc7 Kinase Inhibitors
作者:Reichelt,Andreas; Et Al
参考文献:European Journal Of Medicinal Chemistry 日期:2014 卷标:80 页码:364-382]
3993-78-0 = 815610-16-3
反应条件:1.1 Reagents: Sodium Iodide,Hydrogen Iodide Solvents: Water; 3.5 H,Rt1.2 Reagents: Sodium Carbonate Solvents: Water; Neutralized
标题:Concise Syntheses Of Meridianins And Meriolins Using A Catalytic Domino Amino-Palladation Reaction
作者:Walker,Scott R.; Et Al
参考文献:Organic Letters 日期:2014 卷标:16(3) 页码:708-711]
108-53-2 = 815610-16-3
反应条件:1.1 Reagents: Phosphorus Oxychloride Solvents: Acetonitrile1.2 Reagents: Hydrogen Iodide
标题:Synthesis Of (2-Aminopyrimidin-4-Yl)(Pyridin-4-Yl)Methanone And Derivatives
作者:Giraud,Francis; Et Al
参考文献:Synthesis 日期:2023 卷标:55(22) 页码:3825-3832
📜2-氨基-4-氯嘧啶置于氢碘酸体系中,用 水 作为反应溶剂,化学反应 3.0H,以95%的收率获得产物2-氨基-4-碘嘧啶
参考文献:Synthesis And Structure-activity Relationship Of Trisubstituted Thiazoles As Cdc7 Kinase Inhibitors
标题:Synthesis And Structure-activity Relationship Of Trisubstituted Thiazoles As Cdc7 Kinase Inhibitors
摘要:The Cell Division Cycle 7 (Cdc7) Protein Kinase Is Essential For Dna Replication And Maintenance Of Genome Stability. We Systematically Explored Thiazole-Based Compounds As Inhibitors Of Cdc7 Kinase Activity In Cancer Cells. Our Studies Resulted In The Identification Of A Potent,Selective Cdc7 Inhibitor That Decreased Phosphorylation Of The Direct Substrate Mcm2 In Vitro And In Vivo,And Inhibited Dna Synthesis And Cell Viability In Vitro.
DOI:10.1016/j.Ejmech.2014.04.013
专利信息
专利号:CN-113322490-A
优先权日:2020-02-28
标题:In situ synthesis of copper nanowire array material, preparation method and application thereof
专利号:CN-111170991-B
优先权日:2014-07-11
标题 :Antiproliferative compounds and methods of synthesis thereof
专利号:CN-111170991-A
优先权日:2014-07-11
标 题:Antiproliferative compounds and methods of synthesis thereof
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品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1007/s10593-021-02875-w
摘要:Erkin AV, Krutikov VI, Garabadzhiu AV. Priority directions in the design of biologically active compounds based on 2-aminopyrimidin-4(3H)-one and its derivatives. Chemistry of Heterocyclic Compounds. 2021 Feb;57(2):103–21. doi: 10.1007/s10593-021-02875-w.
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