CAS: 79-42-5; 2-Mercaptopropanoic Acid

该化合物是一种硫酸化合物,其特征为:碳本酸组和硫醇组,其分子配方为C3H6O2S,表明其含有3个碳原子,6个氢原子,2个氧原子和1个硫原子;该化合物一般色素不高,可粉黄,且有强效,不愉快的气味;可溶于水和极有机溶剂中,使其在各种化学应用中具有多种特性;硫酸组的存在具有独特的再活动性,使其得以参与再毒反应和分解酸结,这在生物化学和材料科学中具有重大意义;丙酸,二甲基丙酸通常用于合成药品,农用化学物和有机化学的再剂;此外,该化合物具有抗微生物性特性,在一定的化合物应用中具有一定作用.

结构式图片

欧盟法规

REACH注册ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

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合成工艺路线路线简述

  • 合成目标产物 2-Mercaptopropionic Acid 主要起始原料 Potassium Lactate
  • 5445-17-0 = 79-42-5
    反应条件:1.1 Reagents: 2669091-24-9 Catalysts: Tetrabutylammonium Bromide; 12 H,Rt1.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 2,Rt
    标题:A Convenient Synthesis Of Thiol,Trithiocarbonate And Disulphide
    作者:Gondi,Sudershan R.; Rissing,Christiana Julia; Son,David Y.
    参考文献:Chemrxiv 日期:2021 卷标:1 页码:1-23]

    = 79-42-5
    反应条件:1.1 Reagents: Sodium Carbonate Solvents: Water; Neutralized1.2 Reagents: Sodium Thiosulfate; Rt -> 90 °C; 5 H,80 - 90 °C1.3 Reagents: Sulfuric Acid; 2.5 H,50 - 90 °C1.4 1 H,20 - 40 °C; 40 °C -> 90 °C; 1 H,60 - 90 °C
    标题:Clean Synthesis Process Of 2-Mercaptopropionic Acid
    作者:Zhang,Peng; Wu,Kuixia; Qi,Xin
    参考文献:Shanghai Huagong 日期:2014 卷标:39(2) 页码:17-20]

    6431-92-1 = 79-42-5
    反应条件:1.1 Reagents: Ammonia Solvents: Methanol; 0 °C; 0 °C -> Rt; 1 H,Rt1.2 Reagents: Hydrochloric Acid Solvents: Water; Acidified
    标题:Isothiourea-Catalysed Enantioselective Michael Addition Of N-Heterocyclic Pronucleophiles To α,β-Unsaturated Aryl Esters
    作者:Shu,Chang; Liu,Honglei; Slawin,Alexandra M. Z.; Carpenter-Warren,Cameron; Smith,Andrew D.
    参考文献:Chemical Science 日期:2020 卷标:11(1) 页码:241-247]

    79-42-5 = 79-42-5
    反应条件:1.1 Reagents: Gold Solvents: Ethanol; 10 Min,Rt
    标题:Electrochemical Reduction Of Co2 At Functionalized Au Electrodes
    作者:Fang,Yuxin; Flake,John C.
    参考文献:Journal Of The American Chemical Society 日期:2017 卷标:139(9) 页码:3399-3405]

    79-42-5 + 16056-34-1 = 79-42-5
    反应条件:1.1 Reagents: Ammonium Acetate Solvents: Water; Overnight,Rt
    标题:Analytical Developments For The Determination Of Monomethylmercury Complexes With Low Molecular Mass Thiols By Reverse Phase Liquid Chromatography Hyphenated To Inductively Coupled Plasma Mass Spectrometry
    作者:Bouchet,Sylvain; Bjoern,Erik
    参考文献:Journal Of Chromatography A 日期:2014 卷标:1339 页码:50-58]

    383400-97-3 = 79-42-5
    反应条件:1.1 Reagents: Trifluoroacetic Acid,Triethylsilane Solvents: Dichloromethane
    标题:S-4-Methoxytrityl Mercapto Acids: Synthesis And Application
    作者:Mourtas,S.; Gatos,D.; Kalaitzi,V.; Katakalou,C.; Barlos,K.
    参考文献:Tetrahedron Letters 日期:2001 卷标:42(39) 页码:6965-6967]

    51440-83-6 = 79-42-5
    反应条件:1.1 Reagents: Ammonium Hydroxide Solvents: Ethanol,Water
    标题:Studies On Organic Thio Acids. V
    作者:Biilmann,Einar
    参考文献:Justus Liebigs Annalen Der Chemie 日期:1906 卷标:348 页码:120-143]

    79-42-5 + 2768-02-7 = 79-42-5
    反应条件:1.1 Catalysts: Azobisisobutyronitrile Solvents: Isopropanol; 1 D,Rt; 1 D,60 °C
    标题:Transparent Polyvinylsilsesquioxane Aerogels: Investigations On Synthetic Parameters And Surface Modification
    作者:Shimizu,Taiyo; Kanamori,Kazuyoshi; Nakanishi,Kazuki
    参考文献:Journal Of Sol-Gel Science And Technology 日期:2017 卷标:82(1) 页码:2-14]

    6431-92-1 = 79-42-5
    反应条件:1.1 Reagents: Ammonia Solvents: Methanol1.2 Reagents: Hydrochloric Acid
    标题:Highly Enantioselective Construction Of Tertiary Thioethers And Alcohols Via Phosphine-Catalyzed Asymmetric γ-Addition Reactions Of 5H-Thiazol-4-Ones And 5H-Oxazol-4-Ones: Scope And Mechanistic Understandings
    作者:Wang,Tianli; Yu,Zhaoyuan; Hoon,Ding Long; Huang,Kuo-Wei; Lan,Yu; Et Al
    参考文献:Chemical Science 日期:2015 卷标:6(8) 页码:4912-4922]

    79-42-5 = 79-42-5
    反应条件:1.1 Catalysts: 2,2-Dimethoxy-2-Phenylacetophenone Solvents: Tetrahydrofuran; 15 Min
    标题:Norbornenyl-Based Raft Agents For The Preparation Of Functional Polymers Via Thiol-Ene Chemistry
    作者:Stamenovic,Milan M.; Espeel,Pieter; Van Camp,Wim; Du Prez,Filip E.
    参考文献:Macromolecules (Washington 日期:2011 卷标:44(14) 页码:5619-5630]

    53907-46-3 = 79-42-5 [标题:Reaction Conditions
    标题:A Process For The Preparation Of 2-Mercaptoalkanoate Esters As Intermediates For Agrochemicals,Pharmaceuticals,And Perfumes
    参考文献:Japan]

    = 79-42-5 [标题:Reaction Conditions
    标题:Tetra-Substituted Ethylenes
    作者:Ireland,C. J.; Jones,K.; Pizey,J. S.; Johnson,S.
    参考文献:Synthetic Communications 日期:1976 卷标:6(3) 页码:185-91
2-氨基-5-甲基-噻唑-4-酮置于sodium Hydroxide体系中,化学反应生成 硫代乳酸
参考文献:Andreasch; Zipser,Monatshefte Fur Chemie,1904,Vol. 25,P. 178
标题:Andreasch; Zipser,Monatshefte Fur Chemie,1904,Vol. 25,P. 178

海关参考信息

专利信息


专利号:US-12291596-B2
优先权日:2018-11-30
标 题 :Radical cascade-enabled synthesis of precision polymers with complex main-chain structures
发明人:NIU JIA; HUANG HANCHU; WANG WENQI
权利人:THE TRUSTEES OF BOSTON COLLEGE
摘要:Radical cascade reactions enabling sequence-controlled ring-closing polymerization and ring-opening polymerization for the controlled synthesis of polymers with complex main-chain structures are provided. Facile syntheses leading to low-strain macrocyclic monomers consisting of the ring-opening triggers and extended main-chain structures are also provided. The present disclosure further provides methods for excellent control over polymer molecular weights and molecular weight distributions and high chain-end fidelity allows for the preparation of polymeric systems with well-defined architectures. Further provided are the general nature of the radical cascade-triggered transformations in polymer chemistry, and its application to the synthesis of polymers with diverse main-chain structural motifs with tailored functions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

专利号:US-5549974-A
优先权日:1994-06-23
标题:Methods for the solid phase synthesis of thiazolidinones, metathiazanones, and derivatives thereof
发明人:HOLMES CHRISTOPHER P
权利人:AFFYMAX TECH NV
摘要:The invention provides an efficient and versatile method for the combinatorial synthesis and screening of libraries of 4-thiazolidinones, metathiazanones, and derivatives thereof. In order to expediently synthesize a combinatorial library of derivatives based upon these core structures, a general methodology for the solid phase synthesis of these derivatives is also provided. Arrays of thiazolidinones, metathiazanones, and derivatives thereof useful as peptidomimetics and for the identification of agents having antifungal, antihistaminic, or antimicrobial activity or use in the treatment of inflammation, hypertension, renal failure, congestive heart failure, uremia and other conditions can be prepared using this method.

专利号:US-11186678-B2
优先权日:2018-11-30
标 题 :Radical cascade-enabled synthesis of precision polymers with complex main-chain structures
发明人:NIU JIA; HUANG HANCHU; WANG WENQI
权利人:TRUSTEES BOSTON COLLEGE
摘要:Radical cascade reactions enabling sequence-controlled ring-closing polymerization and ring-opening polymerization for the controlled synthesis of polymers with complex main-chain structures are provided. Facile syntheses leading to low-strain macrocyclic monomers consisting of the ring-opening triggers and extended main-chain structures are also provided. The present disclosure further provides methods for excellent control over polymer molecular weights and molecular weight distributions and high chain-end fidelity allows for the preparation of polymeric systems with well-defined architectures. Further provided are the general nature of the radical cascade-triggered transformations in polymer chemistry, and its application to the synthesis of polymers with diverse main-chain structural motifs with tailored functions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

专利号:US-8835477-B2
优先权日:2009-10-06
标题 :Method for the synthesis of 2-thiohistidine and the like
发明人:ERDELMEIER IRÈNE; DAUNAY SYLVAIN
权利人:ERDELMEIER IRÈNE; DAUNAY SYLVAIN; TETRAHEDRON
摘要:Methods for the synthesis of 2-thiohistidine or a derivative thereof of the formula (I), or of a physiologically acceptable salt, a tautomer, a stereoisomer or a mixture of stereoisomers in any proportions thereof, from a compound of the formula (II) or a physiologically acceptable salt, a tautomer, a stereoisomer or a mixture of stereoisomers in any proportions thereof, by cleavage reaction in the presence of a thiol at a temperature higher than or equal to 60° C. The invention also relates to compounds of the formula (II) and a method for the synthesis thereof.

专利号:US-2023402618-A1
优先权日:2020-10-27
标 题:Method for synthesis of porous monoliths of transition-metal-doped-noble-metal
发明人:SINGH KIRANPAL; BHAT YASH RAJESH; CHARAYA HEMANT; CHAUDHARI VIJAY RAMAN
权利人:LOG 9 MATERIALS SCIENT PRIVATE LIMITED
摘要:The embodiment herein provides a simple, one-pot and scalable methodology for the synthesis of porous monoliths of Transition-metal-doped-noble-metal nanoparticles for cathode catalyst in a metal-air battery, PEMFCs, AFCs, and anode catalyst in water electrolysers. Silver is used as a base material on which doping is done with the transition metals selected from Cu, Co, Mn, Fe, and Ni.

专利号:WO-2011011342-A9
优先权日:2009-07-20
标题:Synthesis of desmopressin
发明人:SRIVASTAVA KRIPA S
权利人:MALLINCKRODT INC; SRIVASTAVA KRIPA S
摘要:The present invention provides a process for the production of desmopressin. In particular, the process provides a process for solid phase synthesis of desmopressin using cyclization of the peptide on the resin.
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主要参考文献

参考标题:3-(Dimethylamino)-2,2-Dimethyl-2H-Azirin Als Aib-äquivalent: Synthese Von Aib-Oligopeptiden
作者:Daniel Obrecht,Heinz Heimgartner |发布日期:1987.2.4
摘要:3-(Dimethylamino)-2,2-Dimethyl-2H-Azirine As An Aib Equivalent; Synthesis Of Aib Oligopeptides

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