CAS: 542-54-1; 4-Methylpentanenitrile

该化合物是一种有机化合物,被归类为硝酸;其特点是五碳链,与第四碳相连,五碳系(-CN),与第二碳相连,甲基组(-CH3),该结构使其具有分支结构,有助于其独特的物理和化学特性;4-甲基苯乙尼特律,典型是一种无色液体,在室内温度下是一种无色液体,具有温和的沸点,表明其分子重量和结构;有机溶剂溶解,但由于碳链的疏水性,该化合物在水中溶解性有限;该化合物用于各种化学合成物,可作为生产药品和农用化学品的一种中间体;与许多硝酸一样,该化合物可以表现出毒性,并应根据适当的安全规程加以处理;其再活性受该子组的存在的影响,该子群体可以参与各种化学反应,包括核糖添加和水解.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

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CAS号107-82-4 溴代异戊烷 | CAS号151-50-8 氰化钾 | CAS号78-77-3 溴代异丁烷 | CAS号75-05-8 乙腈 | CAS号1119-15-9 4-methylpent-2-... | CAS号75917-29-2 2-propylazodiph... | CAS号107-13-1 丙烯腈 | CAS号10285-87-7 Formamide,N-(3-... | CAS号6140-61-0 2,2-二甲基-4-氰基丁醛 | CAS号107-10-8 丙胺 | CAS号1119-29-5 Pentanamide, 4-... | CAS号2999-14-6 4-methyl-1-(2,4... | CAS号78-78-4 异戊烷 | CAS号646-07-1 4-甲基戊酸 | CAS号626-89-1 4-甲基-1-戊醇 | CAS号101948-24-7 methyl 4-methyl... | CAS号1119-16-0 4-甲基戊醛 | CAS号107-83-5 异己烷 | CAS号5344-20-7 4-甲基戊-1-胺 | CAS号54775-00-7 4-Methyl-N-(4-m...

合成工艺路线路线简述

    📜4-Methyl-4-Nitrovaleronitrile置于苯硅烷,三正丁基氢锡体系中,用 甲苯 作为反应溶剂,化学反应 8.0H,以70%的收率获得产物4-甲基戊腈
    参考文献:Bu3Snh-Catalyzed Reduction Of Nitroalkanes To Alkanes
    标题:Bu3Snh-Catalyzed Reduction Of Nitroalkanes To Alkanes
    摘要:
    DOI:10.1021/jo980789K

    海关参考信息

    专利信息


    专利号:US-9879043-B1
    优先权日:2013-06-06
    标 题:Synthesis of non-natural cofactor analogs of S-adenosyl-L-methionine using methionine adenosyltransferase
    发明人:THORSON JON; HUBER TYLER; ZHANG JIANJUN; Singh Shanteri
    权利人:UNIV KENTUCKY RES FOUND
    摘要:The present disclosure relates to the synthesis of non-natural analogs of S-adenosyl-L-methionine (SAM) and/or of Se-adenosyl-L-methionine (SeAM) by reacting a methionine analog and adenosine triphosphate (ATP) in the presence of at least one methionine adenosyltransferase (MAT), and to use thereof with downstream SAM and/or SeAM utilizing enzymes. The non-natural analogs of SAM and/or SeAM have the general formula: n nwhere X is S or Se, and R 1 is an alkyl group.

    专利号:EP-0468457-B1
    优先权日:1990-07-24
    标题 :Novel substituted piperidines and their use as inhibitors of cholesterol synthesis
    发明人:MCCARTHY JAMES R; BARNEY CHARLOTTE L; WANNAMAKER MARION W
    权利人:MERRELL DOW PHARMA
    摘要:The present invention relates to a group of compounds which are novel substituted piperidines and which act to inhibit the synthesis of cholesterol in mammals and in fungi.

    专利号:EP-0420116-B1
    优先权日:1989-09-22
    标 题 :Novel substituted alkyl piperidines and their use as inhibitors of cholesterol synthesis
    发明人:MCCARTHY JAMES RAY; WANNAMAKER MARION WOODS; BARNEY CHARLOTTE LOUISE
    权利人:MERRELL PHARMA INC
    摘要:The present invention relates to a group of compounds which are novel substituted alkyl piperidines and which are useful in the treatment of fungal infections through the inhibition of cholesterol synthesis in mammals.

    专利号:US-6355490-B1
    优先权日:1996-09-13
    标题:Attached tags for use in combinatorial chemistry synthesis
    发明人:HOCHLOWSKI JILL EDIE; SOWIN THOMAS J; NORBECK DANIEL W; GRILLOT ANNE-LAURE MARIE; SWENSON ROLF E
    摘要:The present invention relates to a process of coding and identifying individual members of a chemical combinatorial library synthesized on a plurality of solid supports which undergo mix and split synthesis. The process provides for tagging the solid supports with a coding identifier that is attached to the solid support and which can be decoded by infrared or raman spectroscopy when directly attached to the support.

    专利号:US-11912734-B2
    优先权日:2020-01-28
    标题:Solid-phase synthesis of oligonucleotides containing N6-(2-deoxy-alpha,beta-derythropentofuranosyl)-2,6-diamino-4-hydroxy-5-formamidopyrimidine (Fapyâ‹…dG)
    发明人:GREENBERG MARC M; YANG HAOZHE
    权利人:UNIV JOHNS HOPKINS
    摘要:A strategy using reverse phosphoramidites for synthesizing oligonucleotides containing Fapy·dG is disclosed.

    专利号:US-5217979-A
    优先权日:1989-09-22
    标题:Substituted alkyl piperidines
    发明人:MCCARTHY JAMES R; BARNEY CHARLOTTE L; WANNAMAKER MARION W
    权利人:MERRELL DOW PHARMA
    摘要:The present invention relates to a group of compounds which are novel substituted alkyl piperidines and which act to inhibit the synthesis of cholesterol in mammals and in fungi.

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Drabowicz, J.; Krasowska, D.; Wicha, J., Science of Synthesis, (2009) 48, 258.
    摘要:Faber, K.; Glueck, S. M.; Hammer, S. C.; Hauer, B.; Nestl, B. M., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 3, 571.
    摘要:Nippon Eiseigaku Zasshi. Japanese Journal of Hygiene., 39(423), 1984
    摘要:Galczynski, J.; Huang, H.; Lambert, T. H., Science of Synthesis: Special Topics, (2021) 1, 340.
    摘要:Archives Internationales de Pharmacodynamie et de Therapie., 5(161), 1899
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