CAS: 1459719-81-3; (1S,2S)-2-(3,4-Difluorophenyl)Cyclopropanamine
该化合物是一种具有3,4-二氟联苯替代成分的手性环丙胺衍生物,其立体特性(1S,2S)配置确保精确的分子相互作用,使其对制药和农用化学应用具有价值;二氟联苯组增强了代谢稳定性和生物利用率,而环丙烷环则有助于符合僵硬性,改进了与目标受体的结合性;该化合物是生物活性分子合成的关键中间体,特别是在研制CNS活性药物和酶抑制剂方面,其高纯度和定义明确的立体化学学使其适合于对非对称合成和药用化学的研究;处理要求对含地雷的化合物采取标准的安全防范措施.
- 英文名称(1S,2S)-2-(3,4-Difluorophenyl)Cyclopropanamine
- 中文名称替格瑞洛杂质B
- IUPAC名称(1S,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine
- 其它别名Ticagrelor Impurity 89 Hydrochloride; Ticagrelor-2; Ticagrelor Diastereomer; (1S,2S)-2-(3,4-Difluorophenyl)Cyclopropan-1-Amine Hydrochloride; (1R,2R)-2-(3,4-Difluorophenyl)Cyclopropan-1-Amine Compound With (1S,2S)-2-(3,4-Difluorophenyl)Cyclopropan-1-Amine Dihydrochloride; (1R,2R)-2-(3,4-Difluorophenyl)Cyclopropan-1-Amine Compound With (1S,2S)-2-(3,4-Difluorophenyl)Cyclopropan-1-Amine (1:1) Dihydrochloride; (1R,2R)-2-(3,4-Difluorophenyl); Ticagrelor Related Compound 11
- CAS编号1459719-81-3
- MFCD编号:MFCD30186593
- FDA UNII编号:37OQ6J1I62
- 分子式:C9H9F2N分子量:169.17
- 产品CID: 693390
- 产品分类分析化学 → 标准品 → 药典标准品和杂质标准品
上下游产品
(1R,2R)-trans-2(3,4-difluorophenyl)cyclopropyl carboxamide (E)-3-(3,4-difluorophenyl)acrylic acid trans-(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid 3,4-difluor°Cinnamoyl chloride(3aR,4S,6R,6aS)-6-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol (1S,2R,3S,4R,5S)-4-(6-(((1S,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-2-(phenylethynyl)-9H-purin-9-yl)-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide (3aR,3bS,4aS,5R,5aS)-5-(6-(((1S,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-2-(pyridin-2-ylethynyl)-9H-purin-9-yl)-N,2,2-trimethyltetrahydr°Cyclopropa[3,4]cyclopenta[1,2-d][1,3]dioxole-3b(3aH)-carboxamide (3aR,3bS,4aS,5R,5aS)-5-(6-(((1S,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-2-(phenylethynyl)-9H-purin-9-yl)-N,2,2-trimethyltetrahydr°Cyclopropa[3,4]cyclopenta [1,2-d][1,3]dioxole-3b(3aH)-carboxamide合成工艺路线路线简述
海关参考信息
- 2902600000-乙苯
2902700000-异丙基苯 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:WO-2013144295-A1
优先权日:2012-03-30
标题 :Synthesis of 2-(3,4-difluorophenyl)cyclopropanamine derivatives and salts
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题: Synthesis Of 2-(3,4-Difluorophenyl)Cyclopropanamine Derivatives And Salts Synthèse De Dérivés De La 2-(3,4-Difluorophényl)Cyclopropanamine Et De Sels De Celle-Ci摘要:The Present Invention Relates To The Field Of Organic Synthesis And Describes The Synthesis Of Specific Intermediates Suitable For The Preparation Of Triazolopyrimidine Compounds Such As Ticagrelor.
📝 需求与反馈
尽可能描述清楚需求与问题信息
