CAS: 10130-87-7; 2-Methoxybenzenesulfonyl Chloride

相似化合物

145980-89-8 1261874-92-3 63624-28-2

上下游产品

ortho-methoxybenzenesulfinic acid 2-methoxybenzenediazonium chloride 2-methoxyphenylmagnesium chloride 2-methoxy-phenylamine 1-benzenesulfonyl-2-methoxy-benzene N-(5-pentyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide2-methoxy-N-(5-pentyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide N-Cyclohexyl-2-methoxy-benzenesulfonamide

📜邻甲氧基苯胺置于盐酸,Sodium Nitrite,二氧化硫,Copper Dichloride体系中,用 水,溶剂黄146 用作溶剂,以22%的收率获得2-甲氧基苯磺酰氯
参考文献:血小板活化因子(paf)中的构效关系.11从paf拮抗作用到磷脂酶a(2)抑制:1-芳基磺酰胺基-2-烷基哌嗪的合成与结构活性关系.
标题:血小板活化因子(paf)中的构效关系.11从paf拮抗作用到磷脂酶a(2)抑制:1-芳基磺酰胺基-2-烷基哌嗪的合成与结构活性关系.
摘要:1-苄基-2-烷基哌嗪是i和ii组分泌的pla(2)s的强抑制剂.通过用磺酰胺取代酰胺官能团并通过在苯磺酰基部分的对位引入电子给体取代基,可以提高其活性.哌嗪环的一个碳原子上的位置或该碳原子的绝对构型都不会影响对pla(2)的一个或另一个基团的亲和力,但亲脂性对于这些系列仍然是必不可少的参数.此外,结构活性关系允许这些哌嗪衍生物与pla(2)s催化位点相互作用的新假设.
Doi:10.1016/s0223-5234(01)01274-0

专利信息

专利号:US-5663342-A
优先权日:1994-03-08
标 题 :2-chloro and 2-bromo derivatives of 1,5-iminosugars
发明人：BARTA THOMAS E; MUELLER RICHARD A
权利人:SEARLE & CO
摘要:Novel 2-chloro and 2-bromo derivatives of 1,5-iminosugars are disclosed, especially such derivatives of 1,5-dideoxy-1,5-imino-D-glucitol. These compounds are useful inhibitors of glucosidase enzymes and also are useful as antiviral agents and as intermediates for the synthesis of other enzyme inhibitors and antiviral compounds.

专利号:US-4552984-A
优先权日:1982-01-21
标题 :Process for preparation of α,α-difluoroalkoxy or α,.alpha.
发明人：DESBOIS MICHEL
权利人:RHONE POULENC SPEC CHIM
摘要:A process for the preparation of alpha , alpha -difluoroalkoxy or alpha , alpha -difluoroalkylthiophenyl sulfones, in which a polyhaloalkoxybenzene or a polyhaloalkylthiobenzene is reacted with a sulfonic acid, a derivative or a precursor of this acid, in the presence of boron trifluoride in an amount such that the absolute pressure of the boron trifluoride within the reaction vessel exceeds 1 bar, and in the presence of hydrofluoric acid as a solvent. The resultant products are useful as intermediates in the synthesis of compounds having a phytosanitary (e.g., herbicidal) or pharmaceutical activity.

专利号:US-2010204463-A1
优先权日:2007-08-07
标题 :Preparation Of Synthetic Nucleosides via Pi-Allyl Transition Metal Complex Formation
发明人：LIOTTA DENNIS C; LI YONGFENG
权利人:LIOTTA DENNIS C; LI YONGFENG
摘要:This invention provides highly regioselective and stereoselective processes for preparing synthetic nucleosides. A process for the preparation of synthetic nucleosides is provided that comprises a) preparing a bicycloamide derivative, b) reacting the bicycloamide derivative with a nucleic acid base or heterocyclic base or salt thereof in the presence of a transition metal catalyst to form a cyclopentenecarboxamide, and c) cleaving a carboxamide group from the cyclopentenecarboxamide to form the synthetic nucleoside. The processes according to the invention can be used for the synthesis of a variety of anti-viral agents, including Abacavir, Carbovir, and Entecavir, as well as derivatives thereof.

专利号:US-4554381-A
优先权日:1982-01-21
标题:Process for sulfonylation of halobenzenes
发明人：DESBOIS MICHEL
权利人:RHONE POULENC SPEC CHIM
摘要:A process for sulfonylation of halobenzenes, in which a halobenzene is reacted with a sulfonic acid, a precursor or a derivative thereof in the presence of boron trifluoride in an amount such that the absolute pressure of boron trifluoride within the reaction vessel exceeds 1 bar, and in the presence of hydrofluoric acid as a solvent. The resultant products are useful as intermediates in the synthesis of compounds having a phytosanitary (e.g., herbicidal) or pharmaceutical activity.

专利号:WO-2005058810-A1
优先权日:2003-12-17
标题:Novel intermediates for the synthesis of (r)-tamsulosin and of its pharmaceutically acceptable salts and process for their preparation

专利号:JP-2009505954-A
优先权日:2005-07-21
标题 :Interleukin-1 and tumor necrosis factor-a modifier, synthesis of such modifiers and methods of using such modifiers