CAS: 885588-12-5; 2-Bromo-5-Fluoro-4-Pyridinecarboxylic Acid

相似化合物

885588-14-7 1005291-43-9 1256822-16-8

上下游产品

2-bromo-5-fluoropyridine carbon dioxide methyl 2-bromo-5-fluoro-pyridine-4-carboxylate 4-(azetidine-1-carbonyl)-N-(6-fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-methyl-1H-pyrazole-5-carboxamide methyl 2-((tert-butoxycarbonyl)amino)-5-fluoropyridine-4-carboxylate methyl 2-amino-5-fluoroisonicotinate

2-溴-5-氟吡啶,二氧化碳置于正丁基锂,二异丙胺体系中,用 四氢呋喃,正己烷 作为反应溶剂,化学反应 1.5H,以92%的收率获得产物2-溴-5-氟异烟酸
参考文献:Pyrazole Derivative Manufacturing Method
标题:Pyrazole Derivative Manufacturing Method
摘要:本发明提供了一种制造由化学式(I)表示的化合物的方法.利用这种方法,提供了一种制造4-杂环芳基-N-(2-苯基-[1,2,4]三唑并[1,5-A]吡啶-7-基)-1H-吡唑-5-羧酸酰胺衍生物的方法;以及用于这种制造方法的中间体.

专利信息

专利号:US-9856241-B2
优先权日:2013-07-03
标 题:Substituted benzofuranyl and benzoxazolyl compounds and uses thereof
发明人：BALOGLU ERKAN; SHACHAM SHARON; SENAPEDIS WILLIAM; MCCAULEY DILARA; LANDESMAN YOSEF; GOLAN GALI; KALID ORI; SHECHTER SHARON
权利人:KARYOPHARM THERAPEUTICS INC
摘要:The invention generally relates to substituted benzofuranyl and substituted benzoxazolyl compounds, and more particularly to a compound represented by Structural Formula (A): or a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of Structural Formula (A), or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment of cancer (e.g., mantle cell lymphoma), and other diseases and disorders.

专利号:CN-119462496-A
优先权日:2023-08-08
标 题:Synthesis method of 2-chloro-3-fluoro-6-methylpyridine-4-amine