CAS: 70415-86-0; 1-(Isopropylsulfonyl)-2-Nitrobenzene

上下游产品

CAS号70415-85-9 异丙基(2-硝基苯基)硫烷 | CAS号4875-10-9 邻硝基苯硫酚 | CAS号528-29-0 1,2-二硝基苯 | CAS号75-26-3 2-溴丙烷 | CAS号761440-16-8 2,5-二氯-N-[2-(异丙... | CAS号76697-50-2 1-氨基-2-(异丙基磺酰L)苯

邻硝基苯硫酚置于sodium Hydroxide,双氧水体系中,用 乙醇,溶剂黄146 作为反应溶剂,化学反应 17.58H,反应生成 1-(异丙基磺酰基)-2-硝基苯
参考文献:Notizen Zur Synthese Von 2-Aminophenylsulfonen
标题:Notizen Zur Synthese Von 2-Aminophenylsulfonen
摘要:某些烷基,环烷基和芳基2-氨基苯基砜的合成
DOI:10.1002/hlca.19800630610

专利信息

专利号:US-10329268-B2
优先权日:2013-09-13
标 题 :Processes for preparing medicaments for the treatment of cardiovascular diseases and intermediates for use therein
发明人：RUSSO DOMENICO; WAHNON JORGE; MATON WILLIAM; WEBER BEAT T; JERONIMO PAULA; SOUSA LUISA; BARROCAS PEDRO; PIRES RITA; LIMA RICARDO; VASCONCELOS TEOFILO
权利人:BIAL PORTELA & CA SA
摘要:The present invention provides a compound of formula N wherein: X is CH 2 , oxygen or sulphur; R 1 , R 2 and R 3 are the same or different and signify hydrogens, halogens, alkyl, alkyloxy, hydroxy, nitro, alkylcarbonylamino, alkylamino or dialkylamino group, wherein N is in the form of the individual R- and S-enantiomer or a mixture of the (R)- and (S)-enantiomer. The present invention also provides a compound of formula MA. The present invention also provides processes for preparing the above compounds, and processes involving their use. The compounds are particularly useful as intermediates in the synthesis of peripherally-selective inhibitors of dopamine-β-hydroxylase.

专利号:CN-104592068-A
优先权日:2015-02-05
标题 :One-pot synthesis method of anticancer drug ceritinib intermediate 1-(isopropylsulfonyl)-2-nitrobenzene