CAS: 5053-24-7; 2-(Methylthio)Thiazole

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CAS号5685-05-2 2-巯基噻唑 | CAS号74-88-4 碘甲烷 | CAS号288-47-1 噻唑 | CAS号624-92-0 二甲基二硫醚 | CAS号107-20-0 一氯乙醛 | CAS号16696-83-6 Carbamodithioic... | CAS号19975-56-5 2-(甲基巯基)-2-噻唑啉 | CAS号288-47-1 噻唑 | CAS号672324-84-4 4-(1,3-噻唑-2-基)苯甲腈 | CAS号27088-84-2 2-(4-methoxyphe...

2-(甲基巯基)-2-噻唑啉置于nickel(Iv) Oxide体系中,用 苯 作为反应溶剂,化学反应生成 2-甲硫基噻唑
参考文献:Thiazoles From Cysteinyl Peptides
标题:Thiazoles From Cysteinyl Peptides
摘要:
DOI:10.1021/jo00402A045

专利信息

专利号:US-4388310-A
优先权日:1982-03-01
标 题:6-Amido-2-S-oxides of substituted 2-organothio-pen-2-em-3-carboxylic acids
发明人：CHRISTENSEN BURTON G; DININNO FRANK P; MUTHARD DAVID A; RATCLIFFE RONALD W
权利人:MERCK & CO INC
摘要:Disclosed are 6-amido-2-S-oxides of substituted 2-organothio-pen-2-em-3-carboxylic acids (I) which are useful as antibiotics and as intermediates in the synthesis of substituted pen-2-em-3-carboxylic acids: I wherein: R1 is H or acyl; R2 is hydrogen or methoxyl; R3 is alkyl having from 1-6 carbon atoms; phenylalkyl having 7-12 carbon atoms; and cycloalkyl having 3-6 carbon atoms; and R4 is hydrogen, a removable protecting group or a pharmaceutically acceptable salt or ester moiety.

专利号:US-2021238187-A1
优先权日:2017-04-11
标 题:Aziridine containing epothilone analogs, methods of synthesis, methods of treatment, and drug conjugates
发明人：NICOLAOU KYRIACOS C; RHOADES DEREK; WANG YANGPING
权利人:UNIV RICE WILLIAM M
摘要:In one aspect, the present disclosure provides epothilone analogs of the formula: (I) wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein. Additionally, drug conjugates with cell targeting moieties of the compounds are also provided.

专利号:US-10874646-B2
优先权日:2015-10-16
标 题 :Epothilone analogs, methods of synthesis, methods of treatment, and drug conjugates thereof
发明人：NICOLAOU KYRIACOS C; RHOADES DEREK; WANG YANPING; TOTOKOTSOPOULOS SOTIRIOS
权利人:UNIV RICE WILLIAM M
摘要:In one aspect, the present disclosure provides epothilone analogs of the formula (I) wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein. Additionally, drug conjugates with cell targeting moieties of the compounds are also provided.

专利号:SU-1162806-A1
优先权日:1983-12-08
标题 :2-methylthiothiazole derivatives as semiproducts for synthesis of mesoionic thiazolemonomethinecyanones,method of obtaining same and mesoinic thiazolemonomethylcyanines

专利号:US-4086423-A
优先权日:1973-10-12
标题 :Process for cephem synthesis
发明人：FIRESTONE RAYMOND A; RATCLIFFE RONALD W; CHRISTENSEN BURTON G
权利人:MERCK & CO INC
摘要:Cephalosporin antibiotics of the formula: ##STR1## are produced by cycloaddition of a glycine derivative of the formula ##STR2## with a thiazine derivative of the formula ##STR3##

专利号:CN-114149405-A
优先权日:2021-10-27
标 题:Method and Application of Synthesis of Aromatic Sulfide by Aromatic Exchange Bimetallic Catalysis