CAS: 4507-57-7; Methyl 1-Aminocyclohexane-1-Carboxylate

该化合物是一种有机化合物,其特征是环氧环氧乙烷结构,其特点是一个碳箱状体组和一个氨基组,该化合物通常具有与氨基氨基亚胺和酯有关的特性,包括氨基甲酸酯组和因碳箱色而具有的活性的潜在基础性,该产品可能无色,可粉黄黄色液体或固体,视其具体形式和纯度而定,该物质的存在表明它可能参与氢联结,影响其在水和酒精等极溶剂中的溶解性.此外,甲基-1-氨基环氧碳箱可被用于各种化学合成物,或作为生产药品和农用化学品的中间体.在处理和储存时,应参考安全数据,因为具有地雷功能的化合物可能表现出不同程度的毒性和再活性.总体而言,该混合物是有机化学中一个多用途的建筑块.

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37993-32-1 1144505-90-7 2756-85-6

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上下游产品

CAS号2756-85-6 1-氨基-1-环己基甲酸 | CAS号18107-18-1 (三甲硅烷)重氮甲烷 | CAS号67-56-1 甲醇 | CAS号217299-03-1 4-氨基四氢-2H-吡喃-4-羧酸盐酸盐 | CAS号702-62-5 1,3-二氮杂螺[4.5]癸烷... | CAS号108-94-1 环己酮 | CAS号707-09-5 3-methyl-1,3-di...

合成工艺路线路线简述

    📜环己酮置于barium Dihydroxide,氯化亚砜,水体系中,化学反应 84.0H,反应生成 1-氨基环己甲酸甲酯
    参考文献:Aboul-Enein,M. N.; El-Azzouny,A. A.; Abdallah,N. A.,Egyptian Journal Of Chemistry,1991,Vol. 34,# 6,P. 549-558
    标题:Aboul-Enein,M. N.; El-Azzouny,A. A.; Abdallah,N. A.,Egyptian Journal Of Chemistry,1991,Vol. 34,# 6,P. 549-558

    海关参考信息

    专利信息


    专利号:WO-2023081730-A1
    优先权日:2021-11-03
    标 题:4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide derivatives as cannabinoid cb2 receptor modulators for the treatment of cancer
    发明人：ELZEIN ELFATIH; LIU JIWEN
    权利人:TEON THERAPEUTICS INC
    摘要:The present invention relates to 82 specific 4-hydroxy-2-oxo-1,2- dihydro-1,8-naphthyridine-3-carboxamide derivatives as cannabinoid CB2 receptor modulators for the treatment of cancer, e.g. to 6-(4- fluorophenyl)-4-hydroxy-1-(2-(4-methylpiperazin-1-yl)ethyl)-2-oxo-N- (spiro[2.3]hexan-5-yl)-1,2-dihydro-1,8-naphthyridine-3-carboxamide (example 1, compound 1) The present description discloses the synthesis and characterisation of the 82 claimed compounds as well as biological assays thereof.

    专利号:US-9351954-B2
    优先权日:2009-12-04
    标 题:Multicyclic compounds and methods of use thereof
    发明人：SHAO LIMING; CAMPBELL JOHN EMMERSON; HEWITT MICHAEL CHARLES; CAMPBELL UNA; HANANIA TALEEN G
    权利人:SUNOVION PHARMACEUTICALS INC; PGI DRUG DISCOVERY LLC
    摘要:Provided herein are multicyclic compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. For example, disclosed herein are compounds having formula (IIa) shown below, or a pharmaceutically acceptable salt or stereoisomer thereof, wherein the variables are defined herein. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia.

    专利号:NZ-756518-A
    优先权日:2013-08-26
    标 题 :Pharmaceutical compositions comprising macrolide diastereomers, methods of their synthesis and therapeutic uses

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    合成参考文献


    摘要:Ipaktschi, J.; Saidi, M. R., Science of Synthesis Knowledge Updates, (2012) 4, 480.
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