CAS: 2957-21-3; (S)-5-Hydroxy-2-(4-Hydroxyphenyl)-7-Methoxychroman-4-One

该化合物是一种在花草类亚类下分类的花草类化合物,主要以其存在于各种植物物种中,特别是柑橘水果中闻名,其特点是黄色的橙色,并因其抗氧化特性而得到承认,这有利于潜在的健康利益.Sakurannetin的分子配方为C16H14O5, 其结构包括一个带有氢氧基和甲基氧代成分的铬脊柱.该化合物在植物化学领域引起了人们的兴趣,因为它在防止病原体的植物防护机制及其潜在的治疗应用中的作用,包括防炎和抗癌活动.此外,对沙库兰尼的分子配方进行了研究,以了解其调节各种生物途径的能力,使其成为营养和药理研究的课题.该物质在有机溶剂中的溶解性和水溶性有限是显著的物理特性,影响其提取和在各种配方中的应用.

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上下游产品

5,4′-dihydroxy-7-methoxyflavanone 5-O-β-D-glucopyranoside diazomethane naringenin naringinAcetic acid (S)-2-(4-acetoxy-phenyl)-7-methoxy-4-oxo-chroman-5-yl ester naringenin 5-hydroxy-2-(4'-hydroxyphenyl)-7-methoxybenzopyrilium chloride Acetic acid (S)-2-(4-acetoxy-phenyl)-7-methoxy-chroman-5-yl ester

合成工艺路线路线简述

    📜柚皮苷置于glucosidase Rohapect(R) D5L,Citric-Phosphorus Acid Mcilvaine Buffer体系中,用 甲醇,乙醚 用作溶剂,化学反应 30.0H,反应生成樱花亭
    参考文献:Cyclohexanoid Protoflavanones From The Stem-Bark And Roots Of Ongokea Gore☆
    标题:Cyclohexanoid Protoflavanones From The Stem-Bark And Roots Of Ongokea Gore☆
    摘要:Phytochemical Investigation Of Root And Stem-Bark Of The West African Medicinal Plant Ongokea Gore Resulted In The Isolation Of Four Novel Flavonoids With An Unusual Cyclohexyl Substituent Instead Of The Common Aromatic Ring B. The Structures Of The Isolated Compounds Were Elucidated By Spectroscopic Methods,Mainly Id And 2D NMR. And Subsequently,The Structures Were Corroborated By Chemical Conversion To (-)-(S)-Sakuranetin. The Absolute Configurations,And Preferred Conformations Were Determined By Noe Experiments And Cd Measurements. (C) 2005 Elsevier Ltd. All Rights Reserved.
    Doi:10.1016/j.Phytochem.2005.04.031

    海关参考信息

    专利信息


    专利号:US-11773128-B2
    优先权日:2019-03-28
    标题 :Electrocatalytic synthesis of dihydrochalcones
    发明人:REDKO MIKHAIL; SAFFRON CHRISTOPHER M; JACKSON JAMES E
    权利人:UNIV MICHIGAN STATE
    摘要:The disclosure relates to methods of forming a dihydrochalcone using electrocatalytic dehydrogenation. In particular, the disclosure relates to methods of forming a dihydrochalcone electrocatalytically hydrogenating (ECH) a reactant compound over a catalytic cathode in a reaction medium having a non-alkaline pH value, thereby forming a dihydrochalcone product; wherein the reactant compound has a structure according to Formula (I). The method can be used to prepare dihydrochalcone sweeteners, such as, for example, naringin dihydrochalcone and neohesperidin dihydrochalcone.

    专利号:US-12036300-B2
    优先权日:2021-03-31
    标题:Methods and compositions for improving skin
    发明人:LIAO I-CHIEN; BRIEVA PATRICIA; JUCHAUX FRANCK; BOUEZ CHARBEL; ZHENG QIAN; QIAN KUN
    权利人:OREAL
    摘要:A method for managing skin tone comprising reducing the synthesis of melanin by applying a skin treatment composition to skin. The skin treatment composition may include about 0.1 to about 25 wt. % of acetyl trifluoromethylphenyl valylglycine; about 0.5 to about 30 wt. % of a polyol; about 0.1 to about 30 wt. % of a silicone, fatty compound, or a mixtures thereof, wherein the skin treatment composition is an emulsion, and all weight percentages are based on the total weight of the skin treatment composition.

    专利号:CN-119331888-A
    优先权日:2024-10-10
    标题:Polygonatum cyrtonema PcF3H gene and application thereof in promotion of synthesis of dihydroflavonoid compounds and catalysis of naringenin hydroxylation

    专利号:CN-110408649-B
    优先权日:2019-07-25
    标题:Application of NOR gene and its encoded protein in regulating the synthesis of flavonoids in tomato fruit

    专利号:WO-2020198578-A1
    优先权日:2019-03-28
    标 题:Electrocatalytic synthesis of dihydrochalcones

    专利号:US-2022089630-A1
    优先权日:2019-03-28
    标 题 :Electrocatalytic synthesis of dihydrochalcones

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    主要参考文献


    1: Xiao LY, Chen Y, Duan T, Sun Y, Xu YB, Zhao YJ, Song X, Yan XZ, Hu JG. [Effect of Sakuranetin on Microglia-Mediated Neuroinflammation After Spinal Cord Injury]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2024 Aug 30. Chinese. doi: 10.3881/j.issn.1000-503X.16087. Epub ahead of print.
    949:175015. doi: 10.1016/j.scitotenv.2024.175015. Epub 2024 Jul 26.
    335:118617. doi: 10.1016/j.jep.2024.118617. Epub 2024 Jul 23. 116(3):110850. doi: 10.1016/j.ygeno.2024.110850. Epub 2024 Apr 27. 15(1):3437. doi: 10.1038/s41467-024-47746-y.

    合成参考文献


    参考文献:10.1021/np50001a002
    摘要:Edwards JM, Raffauf RF, Le Quesne PW. Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones. J Nat Prod. 1979 Jan;42(1):85–91. doi: 10.1021/np50001a002.
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