专利号:US-8569560-B2 优先权日:2006-10-13 标题 :Synthesis of terminal alkenes from internal alkenes via olefin metathesis 发明人:SCHRODI YANN; PEDERSON RICHARD L; KAIDO HIROKI; TUPY MICHAEL J 权利人:ELEVANCE RENEWABLE SCIENCES 摘要:This disclosure relates generally to olefin metathesis, and more particularly relates to the synthesis of terminal alkenes from internal alkenes using a cross-metathesis reaction catalyzed by an olefin metathesis catalyst. According to one aspect, for example, a method is provided for synthesizing a terminal olefin, the method comprising contacting, in the presence of a ruthenium alkylidene metathesis catalyst, an olefinic substrate comprised of at least one internal olefin with a cross metathesis partner comprised of an alpha olefinic reactant, under reaction conditions effective to allow cross-metathesis to occur, wherein the reaction conditions include a reaction temperature of at least 35° C. The methods, compositions, reactions and reaction systems herein disclosed have utility in the fields of catalysis, organic synthesis, and industrial chemistry.
专利号:US-2014194584-A1 优先权日:2013-01-07 标题 :Process for the synthesis of w-Unsaturated nitrile-acid/ester in which two types of cross metathesis are alternated consecutively swing process 发明人:DUBOIS JEAN-LUC; COUTURIER JEAN-LUC 权利人:ARKEMA FRANCE 摘要:The invention relates to a process for the synthesis of a monounsaturated nitrile-ester (acid) by cross metathesis starting from an unsaturated compound I comprising at least one trivalent nitrile, acid or ester functional group, characterized in that it comprises a stage in which two types of cross metathesis are alternated consecutively:n a first type of cross metathesis cm1 with an acrylic compound II chosen from acrylonitrile, acrylic acid or an acrylic ester, one of the compounds I or II comprising a nitrile functional group and the other of these compounds II or I comprising an acid or ester functional group, and a second type of cross metathesis cm2 with a light C 2 to C 4 alkene compound III, preferably with ethylene. nn The invention also relates to a process for the synthesis of an α,ω-amino ester (acid) obtained by a process comprising a stage in which the two types of cross metathesis defined above are alternated consecutively, followed by a hydrogenation stage.
专利号:US-9382189-B2 优先权日:2013-02-08 标题:Synthesis of a branched unsaturated compound by means of cross metathesis 发明人:DUBOIS JEAN-LUC; COUTURIER JEAN-LUC 权利人:ARKEMA FRANCE 摘要:The invention relates to a method for the synthesis of a branched unsaturated fatty compound, said method comprising the metathesis, in the presence of a metathesis catalyst, of a linear unsaturated fatty compound and a branched olefin. The branched unsaturated fatty compound is used in particular for the production of at least one of the following products: dielectric fluids, specialty surfactants, emulsifiers, frictions agents, antistatic additives, antifogging additives, mould release agents, pigment dispersants, high-performance lubricants, waxes and wax emulsifiers, polymer conversion additives, PVC stabilizing agents, inks, resins, paints, varnishes, solvents, lipsticks, creams for the skin, deodorants, particularly stick deodorants, hair dyes, shampoos and other liquid soaps, shaving foam, laundry detergents, cleaning agents, fabric softeners, and mixtures of same.
专利号:US-8642792-B2 优先权日:2007-02-15 标题 :Method for the synthesis of omega-amino-alkanoic acids 发明人:DUBOIS JEAN-LUC 权利人:DUBOIS JEAN-LUC; ARKEMA FRANCE 摘要:The invention relates to a method for the synthesis of amino acids/esters of general formula NH 2 —(CH 2 ) n —COOR in which n is an integer between 5 and 14, and R is either H or an alkyl radical including from 1 to 4 carbon atoms, from natural long-chain mono-unsaturated fatty acids or esters including at least 10 adjacent carbon atoms per molecule, said method comprising: first converting, if necessary, said natural long-chain fatty acid or ester into a monounsaturated fatty acid/ester of general formula R 1 —(CH 2 ) m —CHâ•?CH—(CH 2 ) p —COOR in which R 1 is H, CH 3 or a COOR radical, m is an integer between 0 and 14 and p is an integer between 2 and 11, then submitting the latter to a crossed catalytic metathesis reaction with a compound of formula R 2 —CHâ•?CH—R 3 in which R 2 is either H or CN and R 3 is CN or CH 2 NH 2 , provided that if R 2 is CN, R 3 can be only CN, and finally converting the resulting product of the general formula R 3 —CHâ•?CH—(CH 2 ) p —COOR into an amino-acid, either by hydrogenation, or by hydrogenation of the trple terminal bond, or by amination of the double terminal bond.
专利号:US-2023174477-A1 优先权日:2021-12-03 标题:Methods for synthesis of the tricyclic prostaglandin d2 metabolite methyl ester 发明人:DAI MINGJI; SIMS HUNTER 权利人:PURDUE RESEARCH FOUNDATION 摘要:Methods for the synthesis of a tricyclic-prostaglandin D 2 metabolite methyl ester or a pharmaceutically acceptable salt thereof.
专利号:US-9567293-B2 优先权日:2013-02-08 标题 :Combined synthesis of a nitrile-ester/acid and of a diester/diacid 发明人:DUBOIS JEAN-LUC; COUTURIER JEAN-LUC; BRANDHORST MARKUS 权利人:ARKEMA FRANCE 摘要:A method for the combined synthesis of a mono-unsaturated nitrile-ester(acid) and of a bi-functional carbonyl compound, wherein it includes a step including the cross metathesis mc1 of an unsaturated fatty acid/ester compound with an unsaturated nitrile compound, in which mc1 is performed with partial conversion such as to obtain and recover, separately, at least the following products: a mono-unsaturated nitrile-ester/acid and a symmetrical compound, diester or diacid respectively including a double bond located in the middle of the molecular chain of compound, and subsequently a step including the oxidation cleavage cp2 of the double bond of compound, such as to form a single type of carbonyl compound having formula R2-(CH2)n-COR′, in which R′ is H or OH, depending on the operating conditions selected for the oxidation cleavage cp2. Also, the production of monomers for the polymer industry.
[参考文献]: Anastasiya Rybak, Et Al. Acyclic Diene Metathesis With A Monomer From Renewable Resources: Control Of Molecular Weight And One-Step Preparation Of Block Copolymers. Chemsuschem. 2008;1(6):542-7.
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