合成目标产物 2-Chloro-4-Methyl-6-Methylsulfanyl-Pyrimidine 主要起始原料 2,4-Dichloro-6-Methylpyrimidine And Sodium Thiomethoxide
5188-07-8 + 5424-21-5 = 89466-59-1 反应条件:1.1 Solvents: Tetrahydrofuran,Water; 0 °C; 2 H,0 °C1.2 Solvents: Water; 0 °C 标题:Regioselective 2-Amination Of Polychloropyrimidines 作者:Smith,Sean M.; Buchwald,Stephen L. 参考文献:Organic Letters 日期:2016 卷标:18(9) 页码:2180-2183]
6328-58-1 = 89466-59-1 反应条件:1.1 6 Min 标题:Ultrasound-Assisted Green Syntheses Of Novel Pyrimidine Derivatives And Their Comparison With Conventional Methods 作者:Pivazyan,Vergush A.; Ghazaryan,Emma A.; Karapetyan,Armen V.; Shainova,Roza S.; Harutyunyan,Siranush V.; Et Al 参考文献:Beilstein Archives 日期:2022 卷标:1 页码:1-12
专利号:US-7576245-B2 优先权日:2002-07-11 标题:Fluorous tagging and scavenging reactants and methods of synthesis and use thereof 发明人:ZHANG WEI; LUO ZHIYONG 权利人:FLUOROUS TECHNOLOGIES INC 摘要:The present invention includes methods and compositions for increasing the fluorous nature of an organic compound by reacting it with at least one fluorous compound to produce a fluorous tagged organic compound. The increased fluorous nature of the fluorous tagged organic compound can then be utilized to separate the fluorous organic compound from untagged reagents, reactants, catalysts and/or products derived therefrom. The resultant fluorous tagged organic compound can be subjected to subsequent chemical transformations, wherein the fluorous nature of the tagged compound is utilized to increase the ease of separation of the fluorous tagged organic compound from untagged reagents, reactants, catalysts and/or products derived therefrom, after each chemical transformation. The chemical transformations result in a second fluorous tagged organic compound wherein the fluorous nature of the second fluorous tagged organic compound can then be reduced by removing the fluorous group therefrom, thereby producing a second organic compound that may be employed as a pharmaceutical compound or intermediate, or a combinatorial library component.
专利号:US-2004073054-A1 优先权日:2002-07-11 标 题 :New fluorous tagging and scavenging reactants and methods of synthesis and use thereof
专利号:US-2006128957-A1 优先权日:2002-07-11 标题:Fluorous tagging and scavenging reactants and methods of synthesis and use thereof
专利号:US-7060850-B2 优先权日:2002-07-11 标 题 :Fluorous tagging and scavenging reactants and methods of synthesis and use thereof