CAS: 885950-21-0; 3-Bromoimidazo[1,2-A]Pyridine-6-Carbonitrile

相似化合物

886362-00-1 866135-71-9 866135-66-2

专利信息

专利号:US-2025009786-A1
优先权日:2021-09-30
标 题 :Automated synthesis of polymeric dual drugs
发明人：MATRAY TRACY; VANBRUNT MICHAEL; MCCUTCHEON JOHN MICHAEL
权利人:SONY GROUP CORP
摘要:Compounds useful as biologically active compounds with or without fluorescent or colored dyes are disclosed. In some embodiments, the compounds have the following structure (I): (I) or a stereoisomer, tautomer or salt thereof, wherein R1, R2, R3, R4, R5, R6, R7, L1, L2, L3, L4, L5, L6, L7, L8, L9, L10, L11, M1, M2, M3, l, m, n, p, and q are as defined herein. Additional compound, methods of preparation, pharmaceutical compositions, and methods of treatment related to compounds of Structure (I) are also provided.

专利号:US-2004030209-A1
优先权日:2000-11-30
标 题:Method for the production of alkyl aryl sulphonates
发明人：NARBESHUBER THOMAS; STEINBRENNER ULRICH; KRACK GERHARD
摘要:The preparation of alkylaryl compounds takes place by n 1) preparation of a mixture of, on statistical average, predominantly monobranched C 10-14 -olefins by n a) reaction of a C 4 -olefin mixture over a metathesis catalyst for the preparation of an olefin mixture comprising 2-pentene and/or 3-hexene, and optional removal of 2-pentene and/or 3-hexene, followed by dimerization of the resulting 2-pentene and/or 3-hexene over a dimerization catalyst to give a mixture comprising C 10-12 -olefins, and optionally removal of the C 10-12 -olefins, or n b) extraction of predominantly monobranched paraffins from kerosene cuts and subsequent dehydrogenation, or n c) Fischer-Tropsch synthesis of olefins or paraffins, where the paraffins are dehydrogenated, or n d) dimerization of shorter-chain internal olefins, or n e) isomerization of linear olefins or paraffins, where the isomerized paraffins are dehydrogenated, n 2) reaction of the olefin mixture obtained in stage 1) with an aromatic hydrocarbon in the presence of an alkylation catalyst which contains zeolites of the faujasite type.

专利号:EP-3598901-A1
优先权日:2018-07-23
标题:Beta-galactosidase from l. bulgaricus for the synthesis of galactooligosaccharides in whey
发明人：KLEINSCHMIDT THOMAS; FISCHER CHRISTIN; WEICHHARD EDGAR; FLEISCHNER WILHELM
权利人:optiferm GmbH; HOCHSCHULE ANHALT
摘要:The present invention relates to a process for the preparation of galactooligosaccharides (GOS) or a composition containing galactooligosaccharides, in which a beta-galactosidase (also lactase [EC3.2.1.23]) derived from L. bulgaricus (L. delbrueckii spp.bulgaricus) is obtained. at a temperature of 37 ° C or less with a lactose-containing composition such as milk, buffer or whey, e.g. Sweet whey, sour whey, whey concentrate or whey permeate, incubated, or a use of the enzyme for the production of galactooligosaccharides or a galactooligosaccharide-containing composition in such a lactose-containing composition. A method for producing a galactooligosaccharide-containing composition with a defined proportion of DP4 galactooligosaccharides and DP3 galactooligosaccharides in all galactooligosaccharides is also provided. The invention further provides compositions which can be prepared by the processes according to the invention and, in this case, beta-galactosidase prepared in casein peptone medium and processes for their production.

专利号:US-2024350645-A1
优先权日:2021-07-22
标 题 :Automated synthesis of polymeric drugs
发明人：MATRAY TRACY; VANBRUNT MICHAEL; MCCUTCHEON JOHN MICHAEL
权利人:SONY GROUP CORP
摘要:Compounds useful as biologically active compounds are disclosed. The compounds have the following structure (I): or a stereoisomer, tautomer or salt thereof, wherein L 1 , L 2 , L 3 , R 1 R 2 , M, p, q, m, and n are as defined herein. Additional compounds, methods of preparation, pharmaceutical compositions, and methods of treatment related to compounds of Structure (I) are also provided.

专利号:US-9303046-B2
优先权日:2012-08-07
标 题:Process for the preparation of heterocyclic ester derivatives
发明人：BONGARTZ JEAN-PIERRE ANDRÉ MARC; STAPPERS ALFRED ELISABETH; TELEHA CHRISTOPHER A; WEERTS KOEN JOHAN HERMAN; WILSON KENNETH J
权利人:JANSSEN PHARMACEUTICA NV
摘要:The present invention is directed to a process for the preparation of heterocyclic ester derivatives of formula I n nwherein A 1 , SEM, and W 1 are as defined herein. Such compounds are useful as intermediates in the synthesis of derivatives useful as protein tyrosine kinase inhibitors, more particularly inhibitors of c-fms kinase.

专利号:US-5386018-A
优先权日:1991-12-31
标 题:Process of preparing N-substituted aldonamides
发明人：AU VAN; HARICHIAN BIJAN; HILL MICHAEL I; RAYKH MIKHAIL; KRUPA JERRY J
权利人:LEVER BROTHERS CO
摘要:N-substituted aldonamides are synthesized by the reaction of alkylamines and aldonolactone. Commercially available sources of aldonolactones (e.g., lactobiono-1,5-lactone) include aldonic acid (e.g., lactobionic acid). The presence of the acid leads to the formation of an ammonium salt impurity. The ammonium salt formation during the synthesis of N-alkyl aldonamides was minimized by the addition of an external acid. External acids and, optionally, emulsifiers were utilized to substantially reduce or eliminate the formation of an ammonium salt and to obtain N-substituted aldonamides of high purity.