CAS: 63279-13-0; (2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(Hydroxymethyl)-3-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Tetrahydro-2H-Pyran-2-Yl (4R,4As,6Ar,9S,11Ar,11Bs)-9-(((2S,3R,4S,5R,6R)-5-Hydroxy-6-(Hydroxymethyl)-3,4-Bis(((2S,3R,4S,5S,

该化合物是来自Stevia rebaudiana 叶子的高密度,非卡路里甜食器. 作为石丁醇胶片,它表现出优美的甜度,大约是苏克罗斯的200-300倍,具有干净的口味,与其他施特维亚提取物相比,它只有很少的苦味. 它在热和酸性条件下的稳定使其适合广泛的食品和饮料应用. 沙丁鱼D也是非糖性,使它成为糖尿病和低卡路里配方的理想糖替代物. 它的高度纯度和遵守主要监管标准(如FDA GRAS , EFSA) , 保证了商业使用的安全性和有效性.

结构式图片

上下游产品

UDP-glucose stevioside rebaudioside A

合成工艺路线路线简述

    尿苷(5')二氢二磷酰(1)-Alpha-D-葡萄糖置于udp-Glucosyltransferase Ugt76G1,Udp-Glucosyltransferase Ugtsl,Magnesium Chloride体系中,用 Aq. Phosphate Buffer 作为反应溶剂,化学反应 46.0H,反应生成 莱苞迪甙d
    参考文献: High-Purity Steviol Glycosides[fr] Glycosides De Stéviol De Grande Pureté
    标题: High-Purity Steviol Glycosides[fr] Glycosides De Stéviol De Grande Pureté
    摘要:描述了制备高度纯化的甜菊糖苷方法,特别是a,D和m型再黄甜菊苷.这些方法包括利用重组微生物将不同的起始成分转化为目标甜菊糖苷.此外,还披露了新型甜菊糖苷reb D2和reb M2,以及其制备方法.这些高度纯化的再黄甜菊苷可用作无热量甜味剂,用于可食用和可咀嚼的组合物,如任何饮料,糖果,烘焙产品,饼干和口香糖.

    专利信息


    专利号:WO-2024042405-A1
    优先权日:2022-08-26
    标 题:Compositions and methods for the synthesis of bio-based polymers
    发明人:OLIVEIRA ANA; CAPÊTO ANA PAULA; PINTADO MANUELA
    权利人:AMYRIS BIO PRODUCTS PORTUGAL UNIPESSOAL LTDA; UNIV CATOLICA PORTUGUESA
    摘要:The present disclosure provides compositions and methods for the synthesis of bio-based polymers (e.g., polyurethanes and polyesters) from secondary materials produced during a fermentation process. The disclosure also features intermediates produced during these processes, as well as compositions containing the same.

    专利号:US-10533205-B1
    优先权日:2013-10-09
    标 题:Kaurenoic acid glycoside precursors and methods of synthesis
    发明人:ZIPP BRANDON
    权利人:VITALITY BIOPHARMA INC
    摘要:Ent-kaurenoic acid glycoside precursor compositions and synthesis methods are provided. The KA-19-monoside, KA-19-bioside and KA-19-trioside precursors can be used as starting materials for a variety of kaurenoic acid based reactions. The precursors provide alternative synthesis pathways for steviol glycosides to the natural pathway based on Steviol biosynthesis. The alternative synthesis pathways using the precursors also circumvent the rate limiting step of the natural Steviol biosynthesis pathway. The precursors can be used individually or in combination to produce a mixture or individual steviol glycosides such as Rebaudioside A, Rebaudioside D or Rebaudioside M. Control over the precursor quantities and composition allows control over the composition of the resulting steviol glycosides that are finally produced.

    专利号:WO-2014051357-A1
    优先权日:2012-09-28
    标 题 :Composition for improving skin elasticity and wrinkles
    发明人:KIM HYO JIN; LEE SANG HWA; RYU JONG SEONG
    权利人:LG HOUSEHOLD & HEALTH CARE LTD
    摘要:The present invention relates to a composition for improving skin elasticity and wrinkles. More particularly, the present invention relates to a collagen synthesis facilitator, to a cosmetic composition, to a pharmaceutical composition, and to a food composition which facilitate the collagen synthesis of fibroblasts and have excellent effects in improving skin elasticity and reducing wrinkles. Also, the present invention relates to a method for improving skin elasticity and preventing, reducing, or treating skin wrinkles by using the composition.

    专利号:US-2024287479-A1
    优先权日:2021-08-23
    标 题 :Glycosyltransferase mutant, and method for catalytic synthesis of rebaudioside m using glycosyltransferase mutant

    专利号:CN-113862319-A
    优先权日:2021-09-16
    标 题 :Application of ginseng glycosyltransferase in the synthesis of stevia

    专利号:CN-113186141-B
    优先权日:2021-04-08
    标题:A kind of method of efficient synthesis of rebaudioside M by one-pot method
    邦泰生物工程(深圳)有限公司
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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Yang L, Yang M, Deng Z, Luo Z, Yuan Z, Rao Y, Zhang Y. Highly Efficient Biosynthesis of Rebaudioside M8 through Structure-Guided Engineering of Glycosyltransferase UGT94E13. J Agric Food Chem. 2024 Jul 17;72(28):15823-15831. doi: 10.1021/acs.jafc.4c03565. Epub 2024 Jul 3. 19(2):e2300628. doi: 10.1002/biot.202300628.
    12:1334427. doi: 10.3389/fbioe.2024.1334427.
    4: Morissette A, de Wouters d'Oplinter A, Andre DM, Lavoie M, Marcotte B, Varin TV, Trottier J, Pilon G, Pelletier M, Cani PD, Barbier O, Houde VP, Marette A. Rebaudioside D decreases adiposity and hepatic lipid accumulation in a mouse model of obesity. Sci Rep. 2024 Feb 6;14(1):3077. doi: 10.1038/s41598-024-53587-y.

    合成参考文献


    参考文献:10.1248/cpb.25.3437
    摘要:SAKAMOTO I, YAMASAKI K, TANAKA O. Application of 13C NMR spectroscopy to chemistry of plant glycosides: Rebaudiosides-D and -E, new sweet diterpene-glucosides of Stevia rebaudiana Bertoni. Chem. Pharm. Bull. 1977;25(12):3437–9. doi: 10.1248/cpb.25.3437.
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