尿苷(5')二氢二磷酰(1)-Alpha-D-葡萄糖置于udp-Glucosyltransferase Ugt76G1,Udp-Glucosyltransferase Ugtsl,Magnesium Chloride体系中,用 Aq. Phosphate Buffer 作为反应溶剂,化学反应 46.0H,反应生成 莱苞迪甙d 参考文献: High-Purity Steviol Glycosides[fr] Glycosides De Stéviol De Grande Pureté 标题: High-Purity Steviol Glycosides[fr] Glycosides De Stéviol De Grande Pureté 摘要:描述了制备高度纯化的甜菊糖苷方法,特别是a,D和m型再黄甜菊苷.这些方法包括利用重组微生物将不同的起始成分转化为目标甜菊糖苷.此外,还披露了新型甜菊糖苷reb D2和reb M2,以及其制备方法.这些高度纯化的再黄甜菊苷可用作无热量甜味剂,用于可食用和可咀嚼的组合物,如任何饮料,糖果,烘焙产品,饼干和口香糖.
专利信息
专利号:WO-2024042405-A1 优先权日:2022-08-26 标 题:Compositions and methods for the synthesis of bio-based polymers 发明人:OLIVEIRA ANA; CAPÊTO ANA PAULA; PINTADO MANUELA 权利人:AMYRIS BIO PRODUCTS PORTUGAL UNIPESSOAL LTDA; UNIV CATOLICA PORTUGUESA 摘要:The present disclosure provides compositions and methods for the synthesis of bio-based polymers (e.g., polyurethanes and polyesters) from secondary materials produced during a fermentation process. The disclosure also features intermediates produced during these processes, as well as compositions containing the same.
专利号:US-10533205-B1 优先权日:2013-10-09 标 题:Kaurenoic acid glycoside precursors and methods of synthesis 发明人:ZIPP BRANDON 权利人:VITALITY BIOPHARMA INC 摘要:Ent-kaurenoic acid glycoside precursor compositions and synthesis methods are provided. The KA-19-monoside, KA-19-bioside and KA-19-trioside precursors can be used as starting materials for a variety of kaurenoic acid based reactions. The precursors provide alternative synthesis pathways for steviol glycosides to the natural pathway based on Steviol biosynthesis. The alternative synthesis pathways using the precursors also circumvent the rate limiting step of the natural Steviol biosynthesis pathway. The precursors can be used individually or in combination to produce a mixture or individual steviol glycosides such as Rebaudioside A, Rebaudioside D or Rebaudioside M. Control over the precursor quantities and composition allows control over the composition of the resulting steviol glycosides that are finally produced.
专利号:WO-2014051357-A1 优先权日:2012-09-28 标 题 :Composition for improving skin elasticity and wrinkles 发明人:KIM HYO JIN; LEE SANG HWA; RYU JONG SEONG 权利人:LG HOUSEHOLD & HEALTH CARE LTD 摘要:The present invention relates to a composition for improving skin elasticity and wrinkles. More particularly, the present invention relates to a collagen synthesis facilitator, to a cosmetic composition, to a pharmaceutical composition, and to a food composition which facilitate the collagen synthesis of fibroblasts and have excellent effects in improving skin elasticity and reducing wrinkles. Also, the present invention relates to a method for improving skin elasticity and preventing, reducing, or treating skin wrinkles by using the composition.
专利号:US-2024287479-A1 优先权日:2021-08-23 标 题 :Glycosyltransferase mutant, and method for catalytic synthesis of rebaudioside m using glycosyltransferase mutant
专利号:CN-113862319-A 优先权日:2021-09-16 标 题 :Application of ginseng glycosyltransferase in the synthesis of stevia
专利号:CN-113186141-B 优先权日:2021-04-08 标题:A kind of method of efficient synthesis of rebaudioside M by one-pot method
1: Yang L, Yang M, Deng Z, Luo Z, Yuan Z, Rao Y, Zhang Y. Highly Efficient Biosynthesis of Rebaudioside M8 through Structure-Guided Engineering of Glycosyltransferase UGT94E13. J Agric Food Chem. 2024 Jul 17;72(28):15823-15831. doi: 10.1021/acs.jafc.4c03565. Epub 2024 Jul 3. 19(2):e2300628. doi: 10.1002/biot.202300628. 12:1334427. doi: 10.3389/fbioe.2024.1334427. 4: Morissette A, de Wouters d'Oplinter A, Andre DM, Lavoie M, Marcotte B, Varin TV, Trottier J, Pilon G, Pelletier M, Cani PD, Barbier O, Houde VP, Marette A. Rebaudioside D decreases adiposity and hepatic lipid accumulation in a mouse model of obesity. Sci Rep. 2024 Feb 6;14(1):3077. doi: 10.1038/s41598-024-53587-y.
合成参考文献
参考文献:10.1248/cpb.25.3437 摘要:SAKAMOTO I, YAMASAKI K, TANAKA O. Application of 13C NMR spectroscopy to chemistry of plant glycosides: Rebaudiosides-D and -E, new sweet diterpene-glucosides of Stevia rebaudiana Bertoni. Chem. Pharm. Bull. 1977;25(12):3437–9. doi: 10.1248/cpb.25.3437.