CAS: 557-11-9; N-Allylurea

该化合物是有机化合物,其特征为尿素功能组和所有基替代体,看起来像是白色晶状固体,可溶于水和有机溶剂,可多种化学用途.Allylurea的分子结构具有与尿素氮相连的碳碳碳双联(Allyl),有助于其再活动.该化合物经常用于有机合成,可以作为各种化学反应的前体,包括聚合和其他含氮化合物的形成.此外,对Allylurea的潜在生物活动进行了研究,包括它对植物生长和发育的影响.其相对简单的结构允许进行修改,从而可以导致产生一系列具有不同特性的衍生物和在农业和制药等领域的应用.在处理该化合物时,应参考安全数据,如任何化学物质,以确保采取适当的预防措施.

结构式图片

相似化合物

625-52-5 5221-62-5 623-76-7

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

Allylthiourea allylis°Cyanate potassium cyanate 1-amino-2-propene allyl-imidazolidinetrione 1,5,5-triallyl-barbituric acid 2-amino-5-methyloxazoline (2,3-dibromo-propyl)-urea

合成工艺路线路线简述

  • 合成目标产物 Allylurea 主要起始原料 Allyl Alcohol And Urea
  • (文献来源)合成步骤主要原料 Allyl Alcohol 和 Urea
📜烯丙基硫脲置于水体系中,化学反应生成 烯丙基脲
参考文献:Kitaev,G. A.; Uritskaya,A. A.; Yatlova,L. E.,Russian Journal Of Applied Chemistry,1994,Vol. 67,# 10.1,P. 1415-1418
标题:Kitaev,G. A.; Uritskaya,A. A.; Yatlova,L. E.,Russian Journal Of Applied Chemistry,1994,Vol. 67,# 10.1,P. 1415-1418

海关参考信息

专利信息


专利号:US-7737284-B2
优先权日:2001-01-18
标题 :Synthesis of temozolomide and analogs
发明人:KUO SHEN-CHUN; MAS JANET L; HOU DONALD CHEN-TUNG
权利人:SCHERING PLOUGH CORP
摘要:This invention relates to a novel process for the synthesis of Temozolomide, an antitumor compound, and analogs, and to intermediates useful in this novel process.

专利号:US-10385029-B2
优先权日:2014-09-12
标 题:One pot process for synthesis of oxazoline and imidazole compounds from glycerol
发明人:RODE CHANDRASHEKHAR VASANT; PANDYA RAJAN; MANE RASIKA BHARAT
权利人:COUNCIL SCIENT IND RES
摘要:The present invention disclose a single step one pot process for synthesis of oxazoline and imidazole derivatives from glycerol using solid acid metal catalyst with improved yield.

专利号:US-9475814-B2
优先权日:2011-10-03
标题:Chiral N-acyl-5,6,7(8-substituted)-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists, pharmaceutical composition, methods for use in NK-3 receptor mediated disorders and chiral synthesis thereof
发明人:HOVEYDA HAMID R; DUTHEUIL GUILLAUME; FRASER GRAEME L; ROY MARIE-ODILE; EL BOUSMAQUI MOHAMED; BATT FREDERIC
权利人:EUROSCREEN SA
摘要:The present invention relates to novel compounds of Formula I and their use in therapeutic treatments. The invention further relates to a novel chiral synthesis of 5,6,7,(8-substituted)-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazines using N-sp3 protective groups. The invention also provides intermediates for use in the synthesis of compounds of Formula I.

专利号:US-11292873-B2
优先权日:2013-11-05
标 题 :Etheramines prepared from a mixture of two or more multifunctional alcohol initiators, and their use as curatives or intermediates for polymer synthesis
发明人:ZHOU HUI; LEWIS DAVID C; KLEIN HOWARD P; RENKEN TERRY L; PATTERSON LEAH
权利人:HUNTSMAN PETROCHEMICAL LLC
摘要:Implementations described herein generally relate to etheramine mixtures formed from a mixture of two or more multifunctional alcohol initiators, processes for the etheramine mixtures production, and its use as a curing agent or as a raw material in the synthesis of polymers. In one implementation, the process comprises mixing a polyol initiator having a melting point greater than a processing temperature and a polyol initiator having a melting point less than the processing temperature to form a polyol initiator mixture having a melting point less than the processing temperature, charging the polyol initiator mixture to an alkoxylation reaction zone, contacting the polyol initiator mixture with an alkylene oxide in the alkoxylation reaction zone to provide a mixture of alkoxylated precursor polyols and charging the mixture of alkoxylated precursor polyols to a reductive amination zone and reductively aminating the mixture of alkoxylated precursor polyols to form the etheramine mixture.

专利号:US-5686645-A
优先权日:1991-10-24
标题:Synthesis of isocyanate precursors from primary formamides
发明人:FARAJ MAHMOUD K
权利人:ARCO CHEM TECH
摘要:A selective process for the production of unsymmetric carbamates and ureas is disclosed. In the process, a primary formamide is reacted with a dialkyl amine or an alcohol in the presence of a Group VIII transition metal catalyst. The unsymmetric carbamates and ureas are useful precursors to isocyanates.

专利号:US-11015015-B2
优先权日:2016-01-12
标 题 :Co-preparation of polyetheramines and alklyene amines
发明人:ZHOU HUI; KLEIN HOWARD P; LEWIS DAVID C
权利人:HUNTSMAN PETROCHEMICAL LLC
摘要:The present disclosure provides a process for the co-preparation of a polyetheramine and an alkylene amine mixture by aminating a liquid polyol initiator mixture comprising an alkoxylated alcohol and a solid high melting polyol. The polyetheramine and alkylene amine mixture may be used in a variety of applications, such as a curing agent for epoxy resin formulations or as a raw material in the synthesis of polyurea.

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品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

[参考文献]: A Olivier, Et Al. Compatibilization Of Starch-Allylurea Blends By Electron Beam Irradiation: Spectroscopic Monitoring And Assessment Of Grafting Efficiency. Biomacromolecules. 2001 Winter;2(4):1260-6.
[参考文献]: A Olivier, Et Al. Physical Stabilization Of Starch-Allylurea Blends By Eb-Grafting: A Compositional And Structural Study. Biomacromolecules. 2000 Summer;1(2):282-9.
[参考文献]: Daniel J Tetlow, Et Al. Sequential Double α-Arylation Of N-Allylureas By Asymmetric Deprotonation And N→c Aryl Migration. Org Lett. 2010 Dec 3;12(23):5442-5.
[参考文献]: G R Harper, Et Al. Influence Of Surface Coverage With Poly(Ethylene Oxide) On Attachment Of Sterically Stabilized Microspheres To Rat Kupffer Cells In Vitro. Biomaterials. 1995 Apr;16(6):427-39.
[参考文献]: Jonathan A Fritz, Et Al. A New Synthesis Of Imidazolidin-2-Ones Via Pd-Catalyzed Carboamination Of N-Allylureas. Org Lett. 2006 Jun 8;8(12):2531-4.

合成参考文献


摘要:Archives of Environmental Contamination and Toxicology., 14(111), 1985 []
摘要:Schafer, E. W., Jr., and W. A. Bowles Jr. 1985. Acute oral toxicity and repellency of 933 chemicals to house and deer mice. Archives of Environmental Contamination and Toxicology 14:111-129. https://www.aphis.usda.gov/ws/nwrc/chem-effects-db/S_schafer851.pdf
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