CAS: 5465-63-4; (2-Bromophenyl)Methanamine Hydrochloride

上下游产品

CAS号2042-37-7 邻溴苯腈 | CAS号433969-27-8 2-[(B°C-氨基)甲基]苯硼酸 | CAS号2042-37-7 邻溴苯腈 | CAS号162356-92-5 2-Methyl-2-prop... | CAS号162356-90-3 N-B°C-2-溴苄胺 | CAS号114049-82-0 N-[(2-phenylphe... | CAS号879-74-3 1-[(2-bromophen... | CAS号444583-14-6 2-(异吲哚啉-1-基)乙酸甲酯

📜2-溴苯腈置于titanium(Iv) Isopropylate,1,1,3,3-四甲基二硅氧烷,盐酸体系中,用 甲苯,水 作为反应溶剂,化学反应 24.0H,以98%的收率获得产物2-溴苄胺盐酸盐
参考文献:一种温和而有效的还原腈的方法
标题:一种温和而有效的还原腈的方法
摘要:描述了一种使用四甲基二硅氧烷/异丙醇钛(iv)还原体系将腈还原为相应胺的简单而有用的方法.合成方法很简单,几乎可以定量获得伯胺盐酸盐盐.该方法的其他优点,例如易于处理的氢化物源,惰性副产物(即tio 2和低聚硅氧烷),使得制备伯胺非常有吸引力.
DOI:10.1016/j.Tetlet.2009.09.164

专利信息

专利号:US-7968752-B2
优先权日:2003-06-16
标 题:Hydrolytically-resistant boron-containing therapeutics and methods of use
发明人：LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A
权利人:ANACOR PHARMACEUTICALS INC
摘要:Compositions and methods of use of borole derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.

专利号:US-RE48547-E
优先权日:2010-08-23
标 题:Aminopyrimidinecarboxamides as CXCR2 modulators
发明人：MAEDA DEAN Y; ZEBALA JOHN A; SCHULER AARON D
权利人:SYNTRIX BIOSYSTEMS INC
摘要:There are disclosed aminopyrimidinecarboxamide compounds useful as pharmaceutical agents, synthesis processes, and pharmaceutical compositions which include aminopyrimidinecarboxamides compounds. More specifically, there is disclosed a genus of CXCR2 inhibitor compounds that are useful for treating a variety of inflammatory and neoplastic disorders.