O-Pentylmethyl-5-(2-Pyridyl)-L-2-Dihydropyridin-2-One置于盐酸,水,Potassium Carbonate体系中,用 甲苯,水 作为反应溶剂,化学反应 10.0H,反应生成 5-(2-吡啶基)-1,2-二氢吡啶-2-酮 参考文献:Process For Production Of 2,3'-Bipyridyl-6'-One 标题:Process For Production Of 2,3'-Bipyridyl-6'-One
专利号:US-8742118-B2 优先权日:2011-10-27 标题 :Methods for preparing intermediates of perampanel 发明人:FONTANA FRANCESCO; STABILE PAOLO 权利人:F I S —FABBRICA ITALIANA SINT S P A 摘要:Methods for the synthesis of 2-alkoxy-5-(pyridin-2-yl)pyridine of formula I n nor salts thereof are provided.
专利号:US-9695147-B2 优先权日:2013-07-25 标题 :Process for the preparation of perampanel 发明人:BUCHLOVIC MARIAN 权利人:TEVA PHARMACEUTICALS INT GMBH 摘要:The present invention provides intermediates useful for the synthesis of Perampanel and processes employing said intermediates for preparing Perampanel. The invention also provides processes for making the intermediates, crystalline forms of the intermediates and the use of the crystalline forms for preparing Perampanel.
专利号:CN-115160217-A 优先权日:2022-08-04 标 题:A kind of preparation method of perampanel, synthesis intermediate and preparation method of degraded impurities
参考标题:Methods For Preparing Intermediates Of Perampanel 摘要:Methods For The Synthesis Of 2-Alkoxy-5-(Pyridin-2-Yl)Pyridine Of Formula I Or Salts Thereof Are Provided.