CAS: 341-27-5; 3-Fluoro-2-Hydroxybenzoic Acid

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CAS号367-12-4 2-氟苯酚 | CAS号854914-89-9 S-methyl 3-fluo... | CAS号251300-29-5 5-溴-3-氟-2-羟基苯甲酸 | CAS号124-38-9 二氧化碳 | CAS号2105-94-4 4-溴-2-氟苯酚 | CAS号251300-28-4 5-溴-3-氟-2-羟基苯甲醛 | CAS号394-50-3 3-氟水杨醛 | CAS号251300-29-5 5-溴-3-氟-2-羟基苯甲酸 | CAS号70163-98-3 3-氟-2-羟基苯甲酸甲酯

2-氟苯酚置于lithium Hydroxide,三氯化铝,三氯化硼体系中,用 甲醇,1,2-二氯乙烷 用作溶剂,化学反应 10.17H,反应生成3-氟-2-羟基苯甲酸
参考文献:A Short And Efficient Preparation Of Methyl-[1,2,4]Oxadiazolium Derivatives With Plant-Inducing Activity
标题:A Short And Efficient Preparation Of Methyl-[1,2,4]Oxadiazolium Derivatives With Plant-Inducing Activity
摘要:我们开发了一种简练高效的综合方法,从市售的卤代苯酚出发,合成了一系列结构多样性的水杨酸和恶二唑盐衍生物.
Doi:10.1039/b316802F

专利信息

专利号:US-4908380-A
优先权日:1986-11-04
标题:Pharmaceutical compositions
发明人：BREWSTER ANDREW G; BROWN GEORGE R; SMITHERS MICHAEL J
权利人:ICI PLC
摘要:The invention concerns novel pharmaceutical compositions containing a 4(Z)-6-(2,4-diphenyl-1,3-dioxan-5-yl)-alkenoic acid which antagonizes one or more of the actions of thromboxane A2, together with a compound which inhibits the synthesis of thromboxane A2. The compositios are useful as medicines in treating a variety of diseases or medical conditions in which thromboxane A2 and/or other prostanoid contractile substances are involved.

专利号:US-11286270-B2
优先权日:2017-10-11
标 题:Boronic acid derivatives and synthesis thereof
发明人：HECKER SCOTT J; BOYER SERGE HENRI; DIELEMANS HUBERTUS J A; GONZALEZ DE CASTRO ANGELA; DE VRIES ANDREAS H M; LEFORT LAURENT
权利人:QPEX BIOPHARMA INC
摘要:Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the method of use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents, for example, β-lactamase inhibitors (BLIs).

专利号:US-2009137557-A1
优先权日:2005-11-22
标题 :Calcilytic Compounds
发明人：KU THOMAS WEN FU; LIN HONG; LUENGO JUAN I; MARQUIS JR ROBERT W; RAMANJULU JOSHI M; TROUT ROBERT; YAMASHITA DENNIS S
权利人:KU THOMAS WEN FU; LIN HONG; LUENGO JUAN I; MARQUIS JR ROBERT W; RAMANJULU JOSHI M; TROUT ROBERT; YAMASHITA DENNIS S
摘要:Novel calcilytic compounds, pharmaceutical compositions, methods of synthesis and methods of using them are provided.

专利号:EP-0266980-A2
优先权日:1986-11-04
标 题 :Pharmaceutical compositions, comprising a 2,4-diphenyl-1,3-dioxane derivative and an inhibitor of thromboxane A2 synthesis

专利号:EP-0266980-B1
优先权日:1986-11-04
标题:Pharmaceutical compositions, comprising a 2,4-diphenyl-1,3-dioxane derivative and an inhibitor of thromboxane a2 synthesis