CAS: 3296-90-0; 2,2-Bis(Bromomethyl)Propane-1,3-Diol

相似化合物

19184-65-7 1522-92-5 40894-00-6

上下游产品

Pentaerythritol hydrogen bromide sodium hydrogencarbonate °Ctanoic acid o-Tolyloxy-pentaerythrit Bis-(o-tolyloxy)-pentaerythrit 5,5-Bis-bromomethyl-2-(4-chloro-phenoxy)-[1,3,2]dioxaphosphinane 2-oxide 5,5-bis-bromomethyl-2,2-dimethyl-[1,3]dioxane

季戊四醇置于硫酸,氢溴酸,溶剂黄146体系中,用34%的收率获得产物二溴新戊二醇
参考文献:用两亲性janus Glycodendrimers自组装的可编程聚糖配体模拟生物膜
标题:用两亲性janus Glycodendrimers自组装的可编程聚糖配体模拟生物膜
摘要:加速的模块合成产生了18种两亲性janus糖树状聚合物,具有由两个或一个碳水化合物头基或具有非碳水化合物亲水性臂的混合构象形成的三种不同拓扑.通过将它们的thf溶液简单地注入到水或缓冲液中,所有janus化合物就会自组装成均匀,稳定和柔软的单层囊泡,称为糖树状大分子.混合的星座拓扑糖树状大分子被证明在结合植物,细菌和人凝集素方面最有效.具有生物医学相关受体的证据为这种糖类树状小体在靶向药物递送,疫苗和纳米医学的其他领域中的应用提供了有希望的前景.
DOI:10.1002/anie.201403186

专利信息

专利号:WO-0132645-A1
优先权日:1999-11-04
标题:The synthesis of extended bis(ethylenedithio)tetrathiafulvalene derivatives and their dihydroxyl analogues
发明人：OZTURK TURAN; TURKSOY FIGEN; WALLIS JOHN D; UMIT TUNCA
权利人:TUBITAK MARMARA RES CT; OZTURK TURAN; TURKSOY FIGEN; WALLIS JOHN D; UMIT TUNCA
摘要:The present invention describes the synthesis of six novel derivatives of bis(ethylenedithio)tetrathiafulvalene (BEDT-TTF), utilising the recently developed reaction of 1,8-diketones with Lawesson's reagent. These new BEDT-TTF derivatives (1)-(6) have potential to delocalise the positive charges formed during change-transfer salts to the peripheral. In addition to their positive charge delocalisation feature, the compounds (1)-(3) have the potential of being introduced hydrogen bonding groups and the compound (4)-(6) already have hydrogen bonding hydroxyl groups. All the new BEDT-TTF (7) derivatives described in this invention have shown comparative CV measurements with the BEDT-TTF. Each of these bis(ethylenedithio)tetrathiafulvalene derivatives of the present invention has a unique and novel structure which can not be found in the prior art and is useful for the development of new organic charge-transfer complexes.

专利号:US-9777034-B2
优先权日:2013-05-21
标题 :Modular synthesis of amphiphilic Janus glycodendrimers and their self-assembly into glycodendrimersomes
发明人：PERCEC VIRGIL
权利人:UNIV PENNSYLVANIA
摘要:The invention concerns compounds of the formula (I) wherein: Y 1 and Y 2 are independently a monosaccharide or disaccharide; X 1 and X 2 are independently —(R 9 —O) m —, —(R 10 ) p —, —O—(R 11 —O) q —, —R 16 —O—R 17 —O— or a covalent bond; Q 1 and Q 2 are independently a nitrogen-containing heterocycle moiety; Z 1 and Z 2 are independently —(O—R 7 )—, —(O—C(â•?O)—R 8 )a-, —O—C(â•?O)—R 12 —C(=0)-R 13 —, —O—C(â•?O)—R 14 —C(â•?O)—R 15 or a covalent bond; R 7 -R 17 are each independently C 1 -C 6 alkyl; R 1 -R 6 are each independently a linear or branched alkyl group; b, c, d, e, f, and g are 0 or 1, provided b+c+d equals at least 2 and e+f+g equals at least 2; and a, m, p, and q are each an integer from 1-6.

专利号:US-8394351-B2
优先权日:2010-05-25
标题:Synthesis of triazole-based and imidazole-based zinc catalysts
发明人：VALDEZ CARLOS A; SATCHER JR JOE H; AINES ROGER D; BAKER SARAH E
权利人:VALDEZ CARLOS A; SATCHER JR JOE H; AINES ROGER D; BAKER SARAH E; L LIVERMORE NAT SECURITY LLC
摘要:Various methods and structures of complexes and molecules are described herein related to a zinc-centered catalyst for removing carbon dioxide from atmospheric or aqueous environments. According to one embodiment, a method for creating a tris(triazolyl)pentaerythritol molecule includes contacting a pentaerythritol molecule with a propargyl halide molecule to create a trialkyne molecule, and contacting the trialkyne molecule with an azide molecule to create the tris(triazolyl)pentaerythritol molecule. In another embodiment, a method for creating a tris(imidazolyl)pentaerythritol molecule includes alkylating an imidazole 2-carbaldehyde molecule to create a monoalkylated aldehyde molecule, reducing the monoalkylated aldehyde molecule to create an alcohol molecule, converting the alcohol molecule to create an alkyl halide molecule using thionyl halide, and reacting the alkyl halide molecule with a pentaerythritol molecule to create a tris(imidazolyl)pentaerythritol molecule. In another embodiment, zinc is bound to the tris(triazolyl)pentaerythritol molecule to create a zinc-centered tris(triazolyl)pentaerythritol catalyst for removing carbon dioxide from atmospheric or aqueous environments.

专利号:US-5523424-A
优先权日:1994-11-04
标题:Solvent-free process for the synthesis of energetic oxetane monomers
发明人：MALIK ASLAM A; MANSER GERALD E; CARSON ROLAND P; ARCHIBALD THOMAS G
权利人:AEROJET GENERAL CO
摘要:This invention relates to a process for the preparation of mono- and bis(azidomethyl)oxetanes. These compounds are prepared by combining a mono- or bis-X-oxetane (wherein X is, for example, a tosylate, mesylate, halogen, etc.) with an aqueous solution of a metallic azide and a phase transfer catalyst. Mono- and bis(azidomethyl)oxetanes can be polymerized to form homopolymers and copolymers with load bearing polyether backbones and highly energetic pendant groups. Such homopolymers and copolymers of the present invention are useful as energetic binders in high-energy formulations, such as propellants, explosives, and gasifiers.

专利号:US-2009111737-A1
优先权日:1999-05-24
标题:Novel antibacterial agents
发明人：CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.

专利号:US-2010022481-A1
优先权日:2006-08-02
标题 :Drug Carriers, Their Synthesis, and Methods of Use Thereof
发明人：WANG DONG; HEIN CHRISTOPHER; LIU XIN-MING
权利人:WANG DONG; HEIN CHRISTOPHER; LIU XIN-MING
摘要:Drug carriers, methods of synthesizing, and methods of use thereof are provided.