CAS: 26177-43-5; 3-Nitrobenzylammonium Hydrochloride

上下游产品

CAS号619-24-9 间硝基苯腈 | CAS号619-23-8 间硝基氯化苄 | CAS号107484-30-0 1-[(3-nitrophen... | CAS号374554-26-4 3-N-Cbz-氨基甲基苯胺 | CAS号4403-70-7 间氨基苄胺 | CAS号147291-66-5 3-氨基-N-(叔丁氧羰基)苯甲胺 | CAS号238428-26-7 3-甲磺酰氨基苄胺盐酸盐 | CAS号7409-18-9 3-硝基苄胺

间硝基氯化苄置于盐酸,乌洛托品体系中,化学反应生成3-硝基苄胺盐酸盐
参考文献:替代作用.14.水-有机溶剂混合物中的离解常数异常:苄基铵离子和相关系统
标题:替代作用.14.水-有机溶剂混合物中的离解常数异常:苄基铵离子和相关系统
摘要:给出了对于苄基铵,苄基二烷基铵和(2-苯乙基)铵离子的各种水-有机溶剂混合物中的热力学解离常数.与hammett方程(方程式1)的偏差与对羧酸观测到的偏差相似,但符号相反.包含疏水常数π的扩展hammett方程(等式3)产生了非常好的相关性.举例说明了派生的次级正常sigma值.
Doi:10.1002/recl.19921110103

专利信息

专利号:US-7109377-B2
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products
发明人：SCHREIBER STUART L; SHAIR MATTHEW D; TAN DEREK S; FOLEY MICHAEL A; STOCKWELL BRENT R
权利人:HARVARD COLLEGE
摘要:The present invention provides complex compounds reminiscent of natural products and libraries thereof, as well as methods for their production. The inventive compounds and libraries of compounds are reminiscent of natural products in that they contain one or more stereocenters, and a high density and diversity of functionality. In general, the inventive libraries are synthesized from diversifiable scaffold structures, which are synthesized from readily available or easily synthesizable template structures. In certain embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from a shikimic acid based epoxyol template. In other embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from the pyridine-based template isonicotinamide. The present invention also provides a novel ortho-nitrobenzyl photolinker and a method for its synthesis. Furthermore, the present invention provides methods and kits for determining one or more biological activities of members of the inventive libraries. Additionally, the present invention provides pharmaceutical compositions containing one or more library members.

专利号:US-6906046-B2
优先权日:2000-12-22
标题 :Pharmaceutical uses and synthesis of benzobicyclooctanes
发明人：JACKSON RANDY W; DARWISH IHAB; BAUGHMAN TED A; HOWBERT J JEFFRY
权利人:CELLTECH R & D INC
摘要:Benzobicyclooctane compounds, their use in inhibiting cellular events involving TNF-α and IL-8, and in the treatment of inflammation events in general; a combinatorial library of diverse bicyclooctanes and process for their synthesis as a library and as individual compounds.

专利号:US-2003082830-A1
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products

专利号:WO-0006525-A2
优先权日:1998-07-25
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products

专利号:US-6417195-B1
优先权日:1999-02-22
标题 :Isoquinoline derivatives and isoquinoline combinatorial libraries
发明人：LEBL MICHAL
权利人:LION BIOSCIENCE AG
摘要:The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinoline derivatives as well as novel libraries comprised of such compounds.

专利号:US-6448443-B1
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products