CAS: 1322-98-1; Sodium,4-Decan-3-Ylbenzenesulfonate

专利信息

专利号:US-2009023606-A1
优先权日:2004-08-12
标 题:Beaded and Cross-Linked Poly(Aminoalkylene)Matrix and Uses Thereof
发明人：GAVELIN PATRIK; PEHR-REHNBERG NICOLA; JOHANNSEN IB
权利人:VERSAMATRIX AS
摘要:The present invention relates to the synthesis of a beaded and cross-linked, high loading capacity polymer for solid phase synthesis, purification of reaction mixtures, chromatographic separation procedures, and the like. The invention can thus be used for the isolation of molecular entities having an affinity for the polymer beads or a chemical entity attached thereto. The beaded polymer matrix can be formed by cross-linking an optionally substituted poly(aminoalkylene), under inverse suspension or inverse emulsion polymerisation conditions, with a cross-linking unit of functionality ≧2.

专利号:WO-2004099288-A1
优先权日:2003-05-09
标 题:Polyethyleneimine polymers
发明人：MICHAEL ROICE; MELDAL MORTEN
权利人:CARLSBERG AS; MICHAEL ROICE; MELDAL MORTEN
摘要:The present invention relates to the development of a beaded high loading capacity polymer for solid phase synthesis and purification of solution-phase organic synthesis. The matrix comprises cross-linked polyethyleneimine units as in the formula (I), where ñ is a real number of 5-1500, and designates the average degree of polymerisation (dp) of polyethyleneimine, ã and õ are real numbers ranging from O to ñ. The high density primary and secondary amino functional groups on the resin function as the site for the excess reagents to react. In a particular aspect there is provided a cross-linked polymer matrix selected from the group consisting of a cross-linked polymer matrix formed from a macromonomer comprising a polyethyleneimine functionalized with at least one fragment comprising a vinyl group, wherein said fragment can be polymerized using radical or ionic initiators to form the cross-linked polymer matrix, or a cross-linked and beaded polymer matrix formed from a macromonomer comprising a polyethyleneimine and a polyfunctional alkyllating agent, under inverse suspension or inverse emulsion polymerisation conditions.