CAS: 120068-37-3; Fipronil

上下游产品

5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethylthio)-1H-pyrazole-3-carbonitrile 5-amino-4-trifluoromethylsulfinyl-1-(2,6-dichloro-4-trifluoromethylphenyl)-3-thi°Carbamoylpyrazole sulfur dioxide 5-amino-3-bromo-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylthiopyrazoleMB 46513 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethylthio)-1H-pyrazole-3-carbonitrile triethylamine salt of 1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4-trifluoromethylsulfinyl-5-(ethoxyacetamido)pyrazole 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-trifluoromethylsulfinyl-1H-pyrazole-3-carboximidic acid methyl ester

3-氯-4-氨基三氟甲苯置于n-甲基吡咯烷酮,磺酰氯,亚硝基硫酸,双氧水,硼酸,溶剂黄146,三氯乙酸体系中,用 N-甲基吡咯烷酮,二氯甲烷,水,氯苯 用作溶剂,化学反应 28.0H,反应生成氟虫腈
参考文献:Process For Synthesis Fipronil
标题:Process For Synthesis Fipronil
摘要:本公开涉及一种从式iii化合物制备式i三氟甲磺酰基吡唑化合物的过程,其中,R,R1和r2分别代表含卤素基团的基团,R3代表全氟烷基.

专利信息

专利号:US-12221421-B2
优先权日:2019-03-19
标题:Process for synthesis of Fipronil
发明人：GHARDA KEKI HORMUSJI; SHENOY DIWAKAR; SHET LAXMINARAYAN; SAMANGADKAR YATIN; KAWADE ABHIJEET SURESH
权利人:GHARDA CHEMICALS LTD
摘要:A process for the synthesis of fipronil, which is a broad spectrum insecticide of the following chemical structure, is provided.The process provides fipronil with a yield in the range of 75% to 90% and purity in the range of 95% to 97%. By the process, the observed amount of sulfone impurity i.e., 5-amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4-trifluoro methylsulfonyl pyrazole in fipronil is in the range of 0% to 0.5%.

专利号:US-2015239796-A1
优先权日:2014-02-19
标题:One pot synthesis of 18f labeledtrifluoromethylated compounds with difluoro(iodo)methane
发明人：RüHL THOMAS; RISS PATRICK; RAFIQUE WAQAS
权利人:UNIV OSLO
摘要:The present invention relates to compositions and methods for the synthesis of 18 F labeled compounds. In particular, the present invention relates to a copper (I) mediated one pot method for 18 F-trifluoromethylation of aromatic- or heteroaromatic halides with difluoro(iodo)methane (e.g., for use at PET imaging agents).

专利号:WO-2010049789-A1
优先权日:2008-10-27
标 题 :Process for the synthesis of fipronil
发明人：JUELICH ALEXANDER; TILLICH JOACHIM
权利人:DYNAMIT NOBEL AG; JUELICH ALEXANDER; TILLICH JOACHIM
摘要:This invention relates to a process for the continuous synthesis of 5-amino-1-[2,6- dichloro-4-(rifluoromethyl)phenyl]-4-(rifluoromethylsulfinyl)-1H-pyrazole-3-carbonitrile comprising the step of reacting in a solvent 5-amino-1-[2,6-dichloro-4- (trifluoromethyl)phenyl]-4-(trifluoromethylthio)-1H-pyrazole-3-carbonitrile with an oxidizing agent. The process provides a more efficient and more robust process than the existing processes.

专利号:US-RE48674-E
优先权日:2010-07-07
标题 :Method for the synthesis of 5-amino-1-phenyl-3-cyano-4-trifluoromethyl sulfinyl
发明人：PASTORIO ANDREA; BETTI PAOLO
权利人:PASTORIO ANDREA; BETTI PAOLO; FINCHIMICA SRL
摘要:The present invention relates to a method for the preparation of the 5-amino-1-phenyl-3-cyano-4-trifluoromethyl sulfinyl pyrazole having the described general formula (I), particularly preferred for the synthesis of Fipronil I, through oxidation of a compound having the general formula (II) as follows:wherein R1 and R2 are independently hydrogen or halogen, and wherein the oxidizing agent is dichloroperacetic acid.

专利号:US-6747175-B2
优先权日:2000-03-01
标 题:Chlorination of an aniline in a hydrofluoric medium
发明人：KEMPF HUBERT; GUIDOT GILBERT; SAINT-JALMES LAURENT
权利人:RHODIA CHIMIE SA
摘要:The invention concerns a method for the synthesis of chlorinated aniline on the ring and comprising at least a sp3 hybridization carbon atom both perhalogenated and bearing a fluorine atom. Said method is characterized in that it comprises a step which consists in chlorinating a precursor aniline of said chlorinated aniline, said chlorination being carried out in a hydrofluoric medium capable of exchanging chlorine and fluorine in benzyl position. The invention is useful for the synthesis of organofluorinated and/or chlorinated compounds.

专利号:WO-2016118586-A1
优先权日:2015-01-20
标 题 :Lowcost, high yield synthesis of nevirapine
发明人：AHMAD SAEED; GUPTON FRANK; VERGHESES JENSON; MCQUADE TYLER
权利人:UNIV VIRGINIA COMMONWEALTH
摘要:Improved methods of producing the HIV drug substance, nevirapine are provided. The methods employ a cost effective and high yield synthetic methods for preparing the nevirapine building block 2-chloro-3-amino-4-picoline (CAPIC) and 2-cyclopropyl amino nicotinate (Me-CAN), and improvements in other steps of nevirapine synthesis.