CAS: 106-88-7; 1,2-Epoxybutane

上下游产品

CAS号106-98-9 正丁烯 | CAS号930-22-3 3,4-环氧-1-丁烯 | CAS号1873-25-2 丁氯醇 | CAS号592-41-6 1-己烯 | CAS号24068-63-1 2-bromobutan-1-ol | CAS号39972-78-6 2-methyl-2-prop... | CAS号106-99-0 丁二烯 | CAS号2482-57-7 1-溴-2-丁醇 | CAS号106-97-8 丁烷 | CAS号105873-72-1 3-butyl-4-ethyl... | CAS号105873-73-2 3-butyl-5-ethyl... | CAS号4221-99-2 (S)-(+)-2-丁醇 | CAS号71-36-3 正丁醇 | CAS号147794-11-4 2-hydroxybutyl ... | CAS号14869-00-2 1-(Benzyloxy)-2... | CAS号4437-85-8 4-乙基-1,3-二恶烷-2-酮 | CAS号5077-67-8 1-羟基-2-丁酮 | CAS号40348-66-1 (R)-1,2-丁二醇 | CAS号30608-62-9 (|S|)-(-)-1,2-环氧丁烷

异丁醛置于邻苯二甲酸亚胺,联苯,2-丁烯,氧气体系中,用 乙腈 用作溶剂,27.0 °C,2.0 Mpa 条件下,反应 12.0H,以98%的收率获得1,2-环氧丁烷
参考文献:一种有机小分子绿色,高效催化丁烯制备环氧丁烷的方法
标题:一种有机小分子绿色,高效催化丁烯制备环氧丁烷的方法
摘要:本发明公开了一种有机小分子绿色,高效催化丁烯制备环氧丁烷的方法,所述方法以丁烯为原料,加入有机溶剂和催化剂,以异丁醛为共还原剂,以氧气为氧化剂,在室温下,反应压力为0.1~4.5Mpa的条件下制得环氧丁烷;所述催化剂选自环状有机氮氧自由基前体或具有如下式(I),(II),(III)或(Iv)所述结构的化合物中的至少一种;式中r1,R2,R3独立地选自氢原子,烷基,环烷基,芳香基,杂环,羟基,硝基或卤素,或者r2,R3,R4至少两个成环.本发明工艺简单,条件温和,环氧丁烷收率和选择性高,具有非常好的工业应用前景.

专利信息

专利号:US-7247752-B2
优先权日:2004-10-01
标 题 :Methods for the synthesis of astaxanthin
发明人：LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID
权利人:CARDAX PHARMACEUTICALS INC
摘要:A method used for synthesizing intermediates for use in the synthesis of carotenoids and carotenoid analogs, and/or carotenoid derivatives. In some embodiments, the invention includes methods for synthesizing optically active intermediates useful for the synthesis of optically active carotenoids. Synthesis of optically active carotenoids, in one embodiment, may be accomplished by forming an optically active dihydroxy intermediate from ketoisopherone. The optically active dihydroxy intermediate may be converted into optically active astaxanthin derivatives.

专利号:US-2013196019-A1
优先权日:2010-03-18
标 题:Silicon-containing block co-polymers, methods for synthesis and use
发明人：WILLSON C GRANT; BATES CHRISTOPHER M; STRAHAN JEFFREY; ELLISON CHRISTOPHER JOHN; MUELLER BRENNEN
权利人:WILLSON C GRANT; BATES CHRISTOPHER M; STRAHAN JEFFREY; ELLISON CHRISTOPHER JOHN; MUELLER BRENNEN; NAT UNIVERSITY OF SINAPORE
摘要:The present invention describes the synthesis of silicon-containing monomers and copolymers. The synthesis of a monomer, trimethyl-(2-methylenebut-3-enyl)silane (TMSI) and subsequent synthesis of diblock copolymer with styrene, forming polystyrene-block-polytrimethylsilyl isoprene, and synthesis of diblock copolymer Polystyrene-block-polymethacryloxymethyltrimethylsilane or PS-b-P(MTMSMA). These silicon containing diblock copolymers have a variety of uses. One preferred application is as novel imprint template material with sub-100 nm features for lithography.

专利号:US-8222458-B2
优先权日:2008-06-13
标题 :Process or synthesis of (3S)- and (3R)-3-hydroxy-beta-ionone, and their transformation to zeaxanthin and beta-cryptoxanthin
发明人：KHACHIK FREDERICK; CHANG AN-NI
权利人:KHACHIK FREDERICK; CHANG AN-NI; UNIV MARYLAND
摘要:Disclosed is a process for the synthesis of (3R)-3-hydroxy-β-ionone and its (3S)-enantiomer in high optical purity from commercially available (rac)-α-ionone. The key intermediate for the synthesis of these hydroxyionones is 3-keto-α-ionone ketal that was prepared from (rac)-α-ionone after protection of this ketone as a 1,3-dioxolane. Reduction of 3-keto-α-ionone ketal followed by deprotection, lead to 3-hydroxy-α-ionone that was transformed into (rac)-3-hydrox-β-ionone by base-catalyzed double bond isomerization in 46% overall yield from (rac)-α-ionone. The racemic mixture of these hydroxyionones was then resolved by enzyme-mediated acylation in 96% ee. (3R)-3-Hydroxy-β-ionone and its (3S)-enantiomer were respectively transformed to (3R)-3-hydroxy-(β-ionylideneethyl)triphenylphosphonium chloride [(3R)-C 15 -Wittig salt] and its (3S)-enantiomer [(3S)-C 15 -Wittig salt] according to known procedures. Double Wittig condensation of these Wittig salts with commercial available 2,5- dimethtylocta-2,4,6-triene-1,8-dial provided all 3 stereoisomers of zeaxanthin. Similarly, (3R)-C 15 -Wittig and its (3S)-enantiomer were each coupled with β-apo-12′-carotenal.

专利号:WO-2023152730-A1
优先权日:2022-02-14
标题 :Amine-borane adducts in the synthesis of polyester and its copolymers using cyclic esters and compositions thereof
发明人：FENG XIAOSHUANG; LIU JINGJING; GNANOU YVES
权利人:UNIV KING ABDULLAH SCI & TECH
摘要:Embodiments of the present disclosure provide for the process of synthesis of polyester and its copolymers through (co)polymerization of cyclic esters and with other oxygenated monomers using amine-borane adduct. Embodiments of the present disclosure further describe the controlled anionic ring-opening polymerization of the cyclic compounds. Embodiments of the present disclosure also describe the polymerization of cyclic compounds using the synergistic effect of amines and thioureas. Embodiments of the present disclosure also describe compositions of polymers formed by the said process.

专利号:US-9085538-B2
优先权日:2010-07-26
标题:Process for the preparation of key intermediates for the synthesis of statins or pharmaceutically acceptable salts thereof
发明人：CASAR ZDENKO; STERK DAMJAN; JUKIC MARKO
权利人:CASAR ZDENKO; STERK DAMJAN; JUKIC MARKO; LEK PHARMACEUTICALS
摘要:The invention relates to commercially viable process for the synthesis of key intermediates for the preparation of statins, in particular Rosuvastatin and Pitavastatin or respective pharmaceutically acceptable salts thereof. A new simple and short synthetic route for key intermediates is presented which benefits from the use of cheap and readily available starting materials, by which the conventionally most frequently used DIBAL-H as reducing agent can be avoided.

专利号:US-2007049637-A1
优先权日:2003-11-12
标 题:Process for the synthesis of cationic lipids
发明人：DE FERRA LORENZO; ANIBALDI MAURO; AMMIRATI ETTORE
权利人:CHEMI SPA
摘要:A process for the synthesis of lipid cations having general formula (6): n n nin which: R 1 represents a lipophilic chain; R 2 , R 3 , R 4 , which are identical or different from one another, represent C 1 -C 10 alkyl, C 1 -C 10 alkenyl, or C 1 -C 10 alkynyl radicals, optionally containing hydroxyl, ether, halogen and acyloxy functions, and X − is an oxy-anion or a halide; in which a compound of formula (2), n n nin which R 5 and R 6 , which are identical or different from one another, represent a C 1 -C 5 acyl, a benzyl group or a diol-protective group, is reacted in an alcoholic solvent with from 1 to 6 equivalents of NR 2 R 3 R 4 .