CAS: 950455-15-9; N-(3-Chlorobenzyl)-1'H-Spiro[piperidine-4,2'-Quinoxalin]-3'-Amine

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  • 1973481-14-9 = 950455-15-9
    反应条件:1.1 Reagents: Trifluoroacetic Acid Solvents: Dichloromethane; Overnight,Rt
    标题:Spiropyrazine Derivatives As Inhibitors Of Non-Apoptotic Regulated Cell-Death
    参考文献:World Intellectual Property Organization

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1: Kim SE, Zhang L, Ma K, Riegman M, Chen F, Ingold I, Conrad M, Turker MZ, Gao M, Jiang X, Monette S, Pauliah M, Gonen M, Zanzonico P, Quinn T, Wiesner U, Bradbury MS, Overholtzer M. Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth. Nat Nanotechnol. 2016 Nov;11(11):977-985. doi: 10.1038/nnano.2016.164.
2: Cao JY, Dixon SJ. Mechanisms of ferroptosis. Cell Mol Life Sci. 2016 Jun;73(11-12):2195-209. doi: 10.1007/s00018-016-2194-1. Review.
3: Xie Y, Song X, Sun X, Huang J, Zhong M, Lotze MT, Zeh HJ 3rd, Kang R, Tang D. Identification of baicalein as a ferroptosis inhibitor by natural product library screening. Biochem Biophys Res Commun. 2016 May 13;473(4):775-80. doi: 10.1016/j.bbrc.2016.03.052. doi: 10.1002/cbic.201500422. Review. doi: 10.1038/ncb3064.
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